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Statins make you stupid?
Statins make you stupid?
x-no-archive: yes
The side effects of statins: Heart healthy and head harmful?
February 12, 2008 Michael O'Riordan
New York, NY - The cognitive side effects, especially memory loss,
associated with statins resurfaced again this week with an article in
the February 12, 2008 issue of the Wall Street Journal, in which some
doctors voiced concerns that the cholesterol-lowering medications,
specifically atorvastatin (Lipitor, Pfizer), might be helping patients'
hearts but actually putting their memory in jeopardy [1]. To date,
evidence for this effect is only anecdotal.
In the article, Dr Orli Etingin, vice chair of medicine at New York
Presbyterian Hospital, is quoted as saying that atorvastatin, the
best-selling drug on the market, "makes women stupid." Etingin told the
Journal that 24 of her female patients taking atorvastatin lost the
ability to concentrate or recall words. While tests showed nothing
irregular, the women regained full cognitive capacity when the statin
was stopped, and some women did better on other statins.
The examples cited by Etingin, founder and director of the Iris Cantor
Women's Health Center (New York), are anecdotal, but she said more
studies are needed to assess the cognitive effects of statins,
especially in women.
These concerns, despite their observational nature, are not new and have
surfaced in medical journals and meetings, as well as the mainstream
media, for a number of years. As the Journal notes, "Lowering
cholesterol could slow the connections that facilitate thought and
memory. Statins may also lead to the formation of abnormal proteins seen
in the brains of Alzheimer's patients."
The evidence, however, linking statin use to declines in cognitive
function or to the development of diseases such as amyotrophic lateral
sclerosis (ALS), also known as Lou Gehrig's disease, as well as to the
possible protection from Alzheimer's and Parkinson's, are scattershot at
best. In the Journal, reporter Melinda Beck notes that Pfizer, the maker
of atorvastatin, states the drug has been tested in 400 clinical trials,
with no evidence establishing a causal link between atorvastatin and
memory loss. Cardiologist Dr Antonio Gotto (Weill-Cornell Medical
School, NY) believes the benefits of the drugs outweigh the risks,
telling Beck that he "would hate to see people frightened off taking
statins because they think it's going to cause memory loss."
Dr Michael Miller (University of Maryland Medical School, Baltimore)
commented to heartwire that he has heard anecdotal reports of cognitive
declines with statin use but pointed to a recently published paper in
Neurology, with lead investigator Dr Zoe Arvanitakis (Rush University
Medical Center, Chicago, IL), showing that in nearly 1000 patients the
use of statins was not related to incident Alzheimer disease, changes in
cognition, or continuous measures of Alzheimer's pathology or infarction
[2]. Numerous other articles, many covered by heartwire, show
conflicting data supporting and not supporting a link between statin use
and cognitive decline.
Speaking with heartwire, Arvanitakis said that her study involved both
men and women and the results do not contradict the observational
findings but simply do not support the anecdotal evidence seen in
clinical practice.
"There is a lot of interest right now with respect to statins and
cognitive decline and Alzheimer's, so we need to be aware of the
anecdotal evidence," she said. "There are some people who do believe
that statins have a negative effect on cognitive function, and others
who believe it has a beneficial or protective effect, but right now we
just don't know. . . . The bottom line is that the evidence is mixed."
Asked about the cognitive side effects, Dr Roger Blumenthal (Johns
Hopkins University Medical Center, Baltimore) told heartwire he has had
some patients "who think that they are not as sharp mentally on statins,
but the numerator is very small and the denominator is very large." If
there is a good reason to treat a patient with a statin, he'll try
another drug or every-other-day dosing, but he noted that he does not
need to do this frequently, as 90% or more patients "have no problems
with statins."
Still, anecdotally, "the chronology can be very telling," Dr Gayatri
Devi (New York University School of Medicine) told the Journal. She has
treated six patients with memory loss traceable to statin use, with the
changes occurring within six weeks of starting the cholesterol-lowering
drug. "It's a handful of patients, but for them, it made a huge difference."
While cognitive declines occur in men, too, women are affected
particularly harder because they are losing estrogen in menopause,
something that can also cause changes in cognitive function, writes
Beck. She quotes Women's Heart Program director Dr Nieca Goldberg (New
York University School of Medicine) who prescribes statins only to women
with elevated LDL cholesterol and who have already had an MI. For
others, including those with high LDL cholesterol but no risk factors,
Goldberg recommends dietary changes and exercise.
With the evidence all over the map and with observational reports not
going away, studies are being conducted to examine the effects of
statins on "thinking, mood, behavior, and quality of life," writes the
Journal. The researchers, led by Dr Beatrice Golomb (University of
California, San Diego), are collecting anecdotal experiences of patients
on statins. Muscle aches are the most commonly reported side effect,
thus far, with memory problems the second most common side effect, in
approximately 5000 reports to date.
Sources
1. Beck M. Can a drug that helps hearts be harmful to the brain?
Wall Street Journal, February 12, 2008. Available at:
* online.wsj . com /public/us.
2. Arvanitakis Z, Schneider JA, Wilson RS, et al. Statins, incident
Alzheimer disease, change in cognitive function, and neuropathology.
Neurology 2008; DOI:10.1212/01.wnl.0000288181.00826.63. Available at:
* w w w .neurology.org.
Related links
Statins offer no protection against Alzheimer's disease
[HeartWire > Medscape Medical News; Jan 16, 2008]
Link between statins and cognition gets more complicated
[HeartWire > Medscape Medical News; Nov 15, 2007]
Simvastatin linked to reduced incidence of dementia, Parkinson's
disease
[HeartWire > Medscape Medical News; Jul 20, 2007]
WSJ reports on possible interaction between statin use and
development of ALS
[HeartWire > MediaPulse; Jul 04, 2007]
Low LDL, statin use, and Parkinson's disease: Another benefit for
statins or potential harm?
[HeartWire > News; Jan 18, 2007]
Low cholesterol linked to reduced cognitive function
[HeartWire > News; Mar 23, 2005]
x-no-archive: yes
The side effects of statins: Heart healthy and head harmful?
February 12, 2008 Michael O'Riordan
New York, NY - The cognitive side effects, especially memory loss,
associated with statins resurfaced again this week with an article in
the February 12, 2008 issue of the Wall Street Journal, in which some
doctors voiced concerns that the cholesterol-lowering medications,
specifically atorvastatin (Lipitor, Pfizer), might be helping patients'
hearts but actually putting their memory in jeopardy [1]. To date,
evidence for this effect is only anecdotal.
In the article, Dr Orli Etingin, vice chair of medicine at New York
Presbyterian Hospital, is quoted as saying that atorvastatin, the
best-selling drug on the market, "makes women stupid." Etingin told the
Journal that 24 of her female patients taking atorvastatin lost the
ability to concentrate or recall words. While tests showed nothing
irregular, the women regained full cognitive capacity when the statin
was stopped, and some women did better on other statins.
The examples cited by Etingin, founder and director of the Iris Cantor
Women's Health Center (New York), are anecdotal, but she said more
studies are needed to assess the cognitive effects of statins,
especially in women.
These concerns, despite their observational nature, are not new and have
surfaced in medical journals and meetings, as well as the mainstream
media, for a number of years. As the Journal notes, "Lowering
cholesterol could slow the connections that facilitate thought and
memory. Statins may also lead to the formation of abnormal proteins seen
in the brains of Alzheimer's patients."
The evidence, however, linking statin use to declines in cognitive
function or to the development of diseases such as amyotrophic lateral
sclerosis (ALS), also known as Lou Gehrig's disease, as well as to the
possible protection from Alzheimer's and Parkinson's, are scattershot at
best. In the Journal, reporter Melinda Beck notes that Pfizer, the maker
of atorvastatin, states the drug has been tested in 400 clinical trials,
with no evidence establishing a causal link between atorvastatin and
memory loss. Cardiologist Dr Antonio Gotto (Weill-Cornell Medical
School, NY) believes the benefits of the drugs outweigh the risks,
telling Beck that he "would hate to see people frightened off taking
statins because they think it's going to cause memory loss."
Dr Michael Miller (University of Maryland Medical School, Baltimore)
commented to heartwire that he has heard anecdotal reports of cognitive
declines with statin use but pointed to a recently published paper in
Neurology, with lead investigator Dr Zoe Arvanitakis (Rush University
Medical Center, Chicago, IL), showing that in nearly 1000 patients the
use of statins was not related to incident Alzheimer disease, changes in
cognition, or continuous measures of Alzheimer's pathology or infarction
[2]. Numerous other articles, many covered by heartwire, show
conflicting data supporting and not supporting a link between statin use
and cognitive decline.
Speaking with heartwire, Arvanitakis said that her study involved both
men and women and the results do not contradict the observational
findings but simply do not support the anecdotal evidence seen in
clinical practice.
"There is a lot of interest right now with respect to statins and
cognitive decline and Alzheimer's, so we need to be aware of the
anecdotal evidence," she said. "There are some people who do believe
that statins have a negative effect on cognitive function, and others
who believe it has a beneficial or protective effect, but right now we
just don't know. . . . The bottom line is that the evidence is mixed."
Asked about the cognitive side effects, Dr Roger Blumenthal (Johns
Hopkins University Medical Center, Baltimore) told heartwire he has had
some patients "who think that they are not as sharp mentally on statins,
but the numerator is very small and the denominator is very large." If
there is a good reason to treat a patient with a statin, he'll try
another drug or every-other-day dosing, but he noted that he does not
need to do this frequently, as 90% or more patients "have no problems
with statins."
Still, anecdotally, "the chronology can be very telling," Dr Gayatri
Devi (New York University School of Medicine) told the Journal. She has
treated six patients with memory loss traceable to statin use, with the
changes occurring within six weeks of starting the cholesterol-lowering
drug. "It's a handful of patients, but for them, it made a huge difference."
While cognitive declines occur in men, too, women are affected
particularly harder because they are losing estrogen in menopause,
something that can also cause changes in cognitive function, writes
Beck. She quotes Women's Heart Program director Dr Nieca Goldberg (New
York University School of Medicine) who prescribes statins only to women
with elevated LDL cholesterol and who have already had an MI. For
others, including those with high LDL cholesterol but no risk factors,
Goldberg recommends dietary changes and exercise.
With the evidence all over the map and with observational reports not
going away, studies are being conducted to examine the effects of
statins on "thinking, mood, behavior, and quality of life," writes the
Journal. The researchers, led by Dr Beatrice Golomb (University of
California, San Diego), are collecting anecdotal experiences of patients
on statins. Muscle aches are the most commonly reported side effect,
thus far, with memory problems the second most common side effect, in
approximately 5000 reports to date.
Sources
1. Beck M. Can a drug that helps hearts be harmful to the brain?
Wall Street Journal, February 12, 2008. Available at:
* online.wsj . com /public/us.
2. Arvanitakis Z, Schneider JA, Wilson RS, et al. Statins, incident
Alzheimer disease, change in cognitive function, and neuropathology.
Neurology 2008; DOI:10.1212/01.wnl.0000288181.00826.63. Available at:
* w w w .neurology.org.
Related links
Statins offer no protection against Alzheimer's disease
[HeartWire > Medscape Medical News; Jan 16, 2008]
Link between statins and cognition gets more complicated
[HeartWire > Medscape Medical News; Nov 15, 2007]
Simvastatin linked to reduced incidence of dementia, Parkinson's
disease
[HeartWire > Medscape Medical News; Jul 20, 2007]
WSJ reports on possible interaction between statin use and
development of ALS
[HeartWire > MediaPulse; Jul 04, 2007]
Low LDL, statin use, and Parkinson's disease: Another benefit for
statins or potential harm?
[HeartWire > News; Jan 18, 2007]
Low cholesterol linked to reduced cognitive function
[HeartWire > News; Mar 23, 2005]
Re: Statins make you stupid?
convicted neighbor Susan wrote:
>
> The side effects of statins: Heart healthy and head harmful?
>
> February 12, 2008 Michael O'Riordan
>
> New York, NY - The cognitive side effects, especially memory loss,
> associated with statins resurfaced again this week with an article in
> the February 12, 2008 issue of the Wall Street Journal, in which some
> doctors voiced concerns that the cholesterol-lowering medications,
> specifically atorvastatin (Lipitor, Pfizer), might be helping patients'
> hearts but actually putting their memory in jeopardy [1]. To date,
> evidence for this effect is only anecdotal.
>
> In the article, Dr Orli Etingin, vice chair of medicine at New York
> Presbyterian Hospital, is quoted as saying that atorvastatin, the
> best-selling drug on the market, "makes women stupid." Etingin told the
> Journal that 24 of her female patients taking atorvastatin lost the
> ability to concentrate or recall words. While tests showed nothing
> irregular, the women regained full cognitive capacity when the statin
> was stopped, and some women did better on other statins.
>
> The examples cited by Etingin, founder and director of the Iris Cantor
> Women's Health Center (New York), are anecdotal, but she said more
> studies are needed to assess the cognitive effects of statins,
> especially in women.
>
> These concerns, despite their observational nature, are not new and have
> surfaced in medical journals and meetings, as well as the mainstream
> media, for a number of years. As the Journal notes, "Lowering
> cholesterol could slow the connections that facilitate thought and
> memory. Statins may also lead to the formation of abnormal proteins seen
> in the brains of Alzheimer's patients."
>
> The evidence, however, linking statin use to declines in cognitive
> function or to the development of diseases such as amyotrophic lateral
> sclerosis (ALS), also known as Lou Gehrig's disease, as well as to the
> possible protection from Alzheimer's and Parkinson's, are scattershot at
> best. In the Journal, reporter Melinda Beck notes that Pfizer, the maker
> of atorvastatin, states the drug has been tested in 400 clinical trials,
> with no evidence establishing a causal link between atorvastatin and
> memory loss. Cardiologist Dr Antonio Gotto (Weill-Cornell Medical
> School, NY) believes the benefits of the drugs outweigh the risks,
> telling Beck that he "would hate to see people frightened off taking
> statins because they think it's going to cause memory loss."
>
>
> Dr Michael Miller (University of Maryland Medical School, Baltimore)
> commented to heartwire that he has heard anecdotal reports of cognitive
> declines with statin use but pointed to a recently published paper in
> Neurology, with lead investigator Dr Zoe Arvanitakis (Rush University
> Medical Center, Chicago, IL), showing that in nearly 1000 patients the
> use of statins was not related to incident Alzheimer disease, changes in
> cognition, or continuous measures of Alzheimer's pathology or infarction
> [2]. Numerous other articles, many covered by heartwire, show
> conflicting data supporting and not supporting a link between statin use
> and cognitive decline.
>
> Speaking with heartwire, Arvanitakis said that her study involved both
> men and women and the results do not contradict the observational
> findings but simply do not support the anecdotal evidence seen in
> clinical practice.
>
> "There is a lot of interest right now with respect to statins and
> cognitive decline and Alzheimer's, so we need to be aware of the
> anecdotal evidence," she said. "There are some people who do believe
> that statins have a negative effect on cognitive function, and others
> who believe it has a beneficial or protective effect, but right now we
> just don't know. . . . The bottom line is that the evidence is mixed."
>
> Asked about the cognitive side effects, Dr Roger Blumenthal (Johns
> Hopkins University Medical Center, Baltimore) told heartwire he has had
> some patients "who think that they are not as sharp mentally on statins,
> but the numerator is very small and the denominator is very large." If
> there is a good reason to treat a patient with a statin, he'll try
> another drug or every-other-day dosing, but he noted that he does not
> need to do this frequently, as 90% or more patients "have no problems
> with statins."
>
>
> Still, anecdotally, "the chronology can be very telling," Dr Gayatri
> Devi (New York University School of Medicine) told the Journal. She has
> treated six patients with memory loss traceable to statin use, with the
> changes occurring within six weeks of starting the cholesterol-lowering
> drug. "It's a handful of patients, but for them, it made a huge difference."
>
>
> While cognitive declines occur in men, too, women are affected
> particularly harder because they are losing estrogen in menopause,
> something that can also cause changes in cognitive function, writes
> Beck. She quotes Women's Heart Program director Dr Nieca Goldberg (New
> York University School of Medicine) who prescribes statins only to women
> with elevated LDL cholesterol and who have already had an MI. For
> others, including those with high LDL cholesterol but no risk factors,
> Goldberg recommends dietary changes and exercise.
>
>
> With the evidence all over the map and with observational reports not
> going away, studies are being conducted to examine the effects of
> statins on "thinking, mood, behavior, and quality of life," writes the
> Journal. The researchers, led by Dr Beatrice Golomb (University of
> California, San Diego), are collecting anecdotal experiences of patients
> on statins. Muscle aches are the most commonly reported side effect,
> thus far, with memory problems the second most common side effect, in
> approximately 5000 reports to date.
>
>
> Sources
>
> 1. Beck M. Can a drug that helps hearts be harmful to the brain?
> Wall Street Journal, February 12, 2008. Available at:
> * online.wsj . com /public/us.
> 2. Arvanitakis Z, Schneider JA, Wilson RS, et al. Statins, incident
> Alzheimer disease, change in cognitive function, and neuropathology.
> Neurology 2008; DOI:10.1212/01.wnl.0000288181.00826.63. Available at:
> * w w w .neurology.org.
>
>
>
>
> Related links
>
> Statins offer no protection against Alzheimer's disease
> [HeartWire > Medscape Medical News; Jan 16, 2008]
>
> Link between statins and cognition gets more complicated
> [HeartWire > Medscape Medical News; Nov 15, 2007]
>
> Simvastatin linked to reduced incidence of dementia, Parkinson's
> disease
> [HeartWire > Medscape Medical News; Jul 20, 2007]
>
> WSJ reports on possible interaction between statin use and
> development of ALS
> [HeartWire > MediaPulse; Jul 04, 2007]
>
> Low LDL, statin use, and Parkinson's disease: Another benefit for
> statins or potential harm?
> [HeartWire > News; Jan 18, 2007]
>
> Low cholesterol linked to reduced cognitive function
> [HeartWire > News; Mar 23, 2005]
In our collective clinical experience, it is the overeating from the
irrational compulsion to avoid hunger that makes people stupid:
* w w w .thatsfit . com /2008/03/27/risk-of-dementia-increases-with-waistline/
Belly fat doesn't just make your belt a little tighter -- it can be a
risk factor for a host of conditions including certain cancers,
stroke, heart disease, and type 2 diabetes. A recent study shows that
belly fat can also be a risk factor for developing dementia later in
life. In fact, it can be a larger indicator than family history.
More that 6,000 people were included in the study. Those with the most
abdominal fat between ages 40 and 45 were three times more likely to
develop dementia than those with the lowest amount of belly fat.
According to the report, nearly 50% of American adults have an
unhealthy amount of belly fat. And those that are at risk aren't
limited to people who are obese. Many are at a healthy BMI or are only
slightly overweight according to the scale, but carry their excess
weight mostly in their abdomen. At this point, scientists don't know
exactly what the belly fat/dementia link is. Theories include that
belly fat increases the development of amyloid plaques in the brain
(substances that are linked to Alzheimer's) or that dementia is linked
to obesity-related illnesses such as heart disease.
*** end article ***
belly fat = intraabdominal fat = VAT = Black Fat
* HeartMDPhD . com /BlackFat
Therefore, it remains much smarter to simply eat less, down to the
right amount in order to lose all the Black Fat:
* HeartMDPhD . com /BeSmart
Here is a simple parable given in hopes of promoting greater
understanding:
* HeartMDPhD . com /Parable
Be hungry... be healthy... be hungrier... be euglycemic:
* TheWellnessFoundation . com /BeHealthier
Prayerfully in the infinite power and might of the Holy Spirit,
Andrew <><
--
Andrew B. Chung, MD/PhD
Lawful steward of * EmoryCardiology . com
A latter-day disciple of the KING of kings and LORD of lords.
* HeartMDPhD . com /HolySpirit/DiscipleNow
convicted neighbor Susan wrote:
>
> The side effects of statins: Heart healthy and head harmful?
>
> February 12, 2008 Michael O'Riordan
>
> New York, NY - The cognitive side effects, especially memory loss,
> associated with statins resurfaced again this week with an article in
> the February 12, 2008 issue of the Wall Street Journal, in which some
> doctors voiced concerns that the cholesterol-lowering medications,
> specifically atorvastatin (Lipitor, Pfizer), might be helping patients'
> hearts but actually putting their memory in jeopardy [1]. To date,
> evidence for this effect is only anecdotal.
>
> In the article, Dr Orli Etingin, vice chair of medicine at New York
> Presbyterian Hospital, is quoted as saying that atorvastatin, the
> best-selling drug on the market, "makes women stupid." Etingin told the
> Journal that 24 of her female patients taking atorvastatin lost the
> ability to concentrate or recall words. While tests showed nothing
> irregular, the women regained full cognitive capacity when the statin
> was stopped, and some women did better on other statins.
>
> The examples cited by Etingin, founder and director of the Iris Cantor
> Women's Health Center (New York), are anecdotal, but she said more
> studies are needed to assess the cognitive effects of statins,
> especially in women.
>
> These concerns, despite their observational nature, are not new and have
> surfaced in medical journals and meetings, as well as the mainstream
> media, for a number of years. As the Journal notes, "Lowering
> cholesterol could slow the connections that facilitate thought and
> memory. Statins may also lead to the formation of abnormal proteins seen
> in the brains of Alzheimer's patients."
>
> The evidence, however, linking statin use to declines in cognitive
> function or to the development of diseases such as amyotrophic lateral
> sclerosis (ALS), also known as Lou Gehrig's disease, as well as to the
> possible protection from Alzheimer's and Parkinson's, are scattershot at
> best. In the Journal, reporter Melinda Beck notes that Pfizer, the maker
> of atorvastatin, states the drug has been tested in 400 clinical trials,
> with no evidence establishing a causal link between atorvastatin and
> memory loss. Cardiologist Dr Antonio Gotto (Weill-Cornell Medical
> School, NY) believes the benefits of the drugs outweigh the risks,
> telling Beck that he "would hate to see people frightened off taking
> statins because they think it's going to cause memory loss."
>
>
> Dr Michael Miller (University of Maryland Medical School, Baltimore)
> commented to heartwire that he has heard anecdotal reports of cognitive
> declines with statin use but pointed to a recently published paper in
> Neurology, with lead investigator Dr Zoe Arvanitakis (Rush University
> Medical Center, Chicago, IL), showing that in nearly 1000 patients the
> use of statins was not related to incident Alzheimer disease, changes in
> cognition, or continuous measures of Alzheimer's pathology or infarction
> [2]. Numerous other articles, many covered by heartwire, show
> conflicting data supporting and not supporting a link between statin use
> and cognitive decline.
>
> Speaking with heartwire, Arvanitakis said that her study involved both
> men and women and the results do not contradict the observational
> findings but simply do not support the anecdotal evidence seen in
> clinical practice.
>
> "There is a lot of interest right now with respect to statins and
> cognitive decline and Alzheimer's, so we need to be aware of the
> anecdotal evidence," she said. "There are some people who do believe
> that statins have a negative effect on cognitive function, and others
> who believe it has a beneficial or protective effect, but right now we
> just don't know. . . . The bottom line is that the evidence is mixed."
>
> Asked about the cognitive side effects, Dr Roger Blumenthal (Johns
> Hopkins University Medical Center, Baltimore) told heartwire he has had
> some patients "who think that they are not as sharp mentally on statins,
> but the numerator is very small and the denominator is very large." If
> there is a good reason to treat a patient with a statin, he'll try
> another drug or every-other-day dosing, but he noted that he does not
> need to do this frequently, as 90% or more patients "have no problems
> with statins."
>
>
> Still, anecdotally, "the chronology can be very telling," Dr Gayatri
> Devi (New York University School of Medicine) told the Journal. She has
> treated six patients with memory loss traceable to statin use, with the
> changes occurring within six weeks of starting the cholesterol-lowering
> drug. "It's a handful of patients, but for them, it made a huge difference."
>
>
> While cognitive declines occur in men, too, women are affected
> particularly harder because they are losing estrogen in menopause,
> something that can also cause changes in cognitive function, writes
> Beck. She quotes Women's Heart Program director Dr Nieca Goldberg (New
> York University School of Medicine) who prescribes statins only to women
> with elevated LDL cholesterol and who have already had an MI. For
> others, including those with high LDL cholesterol but no risk factors,
> Goldberg recommends dietary changes and exercise.
>
>
> With the evidence all over the map and with observational reports not
> going away, studies are being conducted to examine the effects of
> statins on "thinking, mood, behavior, and quality of life," writes the
> Journal. The researchers, led by Dr Beatrice Golomb (University of
> California, San Diego), are collecting anecdotal experiences of patients
> on statins. Muscle aches are the most commonly reported side effect,
> thus far, with memory problems the second most common side effect, in
> approximately 5000 reports to date.
>
>
> Sources
>
> 1. Beck M. Can a drug that helps hearts be harmful to the brain?
> Wall Street Journal, February 12, 2008. Available at:
> * online.wsj . com /public/us.
> 2. Arvanitakis Z, Schneider JA, Wilson RS, et al. Statins, incident
> Alzheimer disease, change in cognitive function, and neuropathology.
> Neurology 2008; DOI:10.1212/01.wnl.0000288181.00826.63. Available at:
> * w w w .neurology.org.
>
>
>
>
> Related links
>
> Statins offer no protection against Alzheimer's disease
> [HeartWire > Medscape Medical News; Jan 16, 2008]
>
> Link between statins and cognition gets more complicated
> [HeartWire > Medscape Medical News; Nov 15, 2007]
>
> Simvastatin linked to reduced incidence of dementia, Parkinson's
> disease
> [HeartWire > Medscape Medical News; Jul 20, 2007]
>
> WSJ reports on possible interaction between statin use and
> development of ALS
> [HeartWire > MediaPulse; Jul 04, 2007]
>
> Low LDL, statin use, and Parkinson's disease: Another benefit for
> statins or potential harm?
> [HeartWire > News; Jan 18, 2007]
>
> Low cholesterol linked to reduced cognitive function
> [HeartWire > News; Mar 23, 2005]
In our collective clinical experience, it is the overeating from the
irrational compulsion to avoid hunger that makes people stupid:
* w w w .thatsfit . com /2008/03/27/risk-of-dementia-increases-with-waistline/
Belly fat doesn't just make your belt a little tighter -- it can be a
risk factor for a host of conditions including certain cancers,
stroke, heart disease, and type 2 diabetes. A recent study shows that
belly fat can also be a risk factor for developing dementia later in
life. In fact, it can be a larger indicator than family history.
More that 6,000 people were included in the study. Those with the most
abdominal fat between ages 40 and 45 were three times more likely to
develop dementia than those with the lowest amount of belly fat.
According to the report, nearly 50% of American adults have an
unhealthy amount of belly fat. And those that are at risk aren't
limited to people who are obese. Many are at a healthy BMI or are only
slightly overweight according to the scale, but carry their excess
weight mostly in their abdomen. At this point, scientists don't know
exactly what the belly fat/dementia link is. Theories include that
belly fat increases the development of amyloid plaques in the brain
(substances that are linked to Alzheimer's) or that dementia is linked
to obesity-related illnesses such as heart disease.
*** end article ***
belly fat = intraabdominal fat = VAT = Black Fat
* HeartMDPhD . com /BlackFat
Therefore, it remains much smarter to simply eat less, down to the
right amount in order to lose all the Black Fat:
* HeartMDPhD . com /BeSmart
Here is a simple parable given in hopes of promoting greater
understanding:
* HeartMDPhD . com /Parable
Be hungry... be healthy... be hungrier... be euglycemic:
* TheWellnessFoundation . com /BeHealthier
Prayerfully in the infinite power and might of the Holy Spirit,
Andrew <><
--
Andrew B. Chung, MD/PhD
Lawful steward of * EmoryCardiology . com
A latter-day disciple of the KING of kings and LORD of lords.
* HeartMDPhD . com /HolySpirit/DiscipleNow
Re: Satins make you stupid?
Andrew B. Chung, MD/PhD wrote:
> Be hungry... be healthy... be hungrier... be euglycemic:
Chung hungy for more? I tired o spam and want nore mo.
* groups.google . com /group/i-hate-andrew-b-chung-mdphds-spam
stop by and share your jokes.. show a sense of humor:)
KFC 1:9 Let the chicken of low degree rejoice in that he is fried:
KFC 1:10 But the rich, in that he is made full: because as the flavor
of the chick he shall pass away.
KFC 1:11 For the chick is no sooner risen with a burning heat, but it
withereth the chips, and the potato thereof broileth, and the grace of
the fashion of it perisheth: so also shall the rich man eat away in
his ways.
Each man must look to himself to teach him the meaning of life. It is
not something discovered: it is something molded.
Antoine de Saint-Exupery
Andrew B. Chung, MD/PhD wrote:
> Be hungry... be healthy... be hungrier... be euglycemic:
Chung hungy for more? I tired o spam and want nore mo.
* groups.google . com /group/i-hate-andrew-b-chung-mdphds-spam
stop by and share your jokes.. show a sense of humor:)
KFC 1:9 Let the chicken of low degree rejoice in that he is fried:
KFC 1:10 But the rich, in that he is made full: because as the flavor
of the chick he shall pass away.
KFC 1:11 For the chick is no sooner risen with a burning heat, but it
withereth the chips, and the potato thereof broileth, and the grace of
the fashion of it perisheth: so also shall the rich man eat away in
his ways.
Each man must look to himself to teach him the meaning of life. It is
not something discovered: it is something molded.
Antoine de Saint-Exupery
* HeartMDPhD . com /OAF
* HeartMDPhD . com /OAF
<><
* HeartMDPhD . com /HolySpirit/Warns
* HeartMDPhD . com /OAF
<><
* HeartMDPhD . com /HolySpirit/Warns
Re: * CelestialChicken.org/FriedEgg/EnjoyLife
On Wed, 23 Apr 2008 14:49:23 -0500, Andrew B. Chung, MD/PhD wrote
>
> * HeartMDPhD . com /HolySpirit/Warns
The Fried Egg does not have to warn becuase He realizes a good chicken dinner
with family and good friends is happiness.
* CelestialChicken.org/FriedEgg/EnjoyLife
On Wed, 23 Apr 2008 14:49:23 -0500, Andrew B. Chung, MD/PhD wrote
>
> * HeartMDPhD . com /HolySpirit/Warns
The Fried Egg does not have to warn becuase He realizes a good chicken dinner
with family and good friends is happiness.
* CelestialChicken.org/FriedEgg/EnjoyLife
Reply from: -- messaggio eliminato --
Date: 23 Apr 2008, 22:09
-- deleted messages --
Re: Statins make you stupid?
Susan <nevermind@nomail . com > wrote in news:679dcvF2m9si0U1
@mid.individual . net :
> With the evidence all over the map and with observational reports not
> going away, studies are being conducted to examine the effects of
> statins on "thinking, mood, behavior, and quality of life," writes the
> Journal. The researchers, led by Dr Beatrice Golomb (University of
> California, San Diego), are collecting anecdotal experiences of patients
> on statins. Muscle aches are the most commonly reported side effect,
> thus far, with memory problems the second most common side effect, in
> approximately 5000 reports to date.
Hey, wait a minute! Isn't that the same Dr. Golomb who is a paid shill for
the statin industry??? Did you see that study she did that showed statins
lowered blood pressure? Who would believe her?
;-)
Susan <nevermind@nomail . com > wrote in news:679dcvF2m9si0U1
@mid.individual . net :
> With the evidence all over the map and with observational reports not
> going away, studies are being conducted to examine the effects of
> statins on "thinking, mood, behavior, and quality of life," writes the
> Journal. The researchers, led by Dr Beatrice Golomb (University of
> California, San Diego), are collecting anecdotal experiences of patients
> on statins. Muscle aches are the most commonly reported side effect,
> thus far, with memory problems the second most common side effect, in
> approximately 5000 reports to date.
Hey, wait a minute! Isn't that the same Dr. Golomb who is a paid shill for
the statin industry??? Did you see that study she did that showed statins
lowered blood pressure? Who would believe her?
;-)
Re: Statins make you stupid?
x-no-archive: yes
listener wrote:
> Hey, wait a minute! Isn't that the same Dr. Golomb who is a paid shill for
> the statin industry??? Did you see that study she did that showed statins
> lowered blood pressure? Who would believe her?
I never said that about her, I said it about YOU.
Susan
x-no-archive: yes
listener wrote:
> Hey, wait a minute! Isn't that the same Dr. Golomb who is a paid shill for
> the statin industry??? Did you see that study she did that showed statins
> lowered blood pressure? Who would believe her?
I never said that about her, I said it about YOU.
Susan
Re: Statins make you stupid?
In article <679mccF2nn9h7U1@mid.individual . net >,
Susan <nevermind@nomail . com > wrote:
> x-no-archive: yes
>
> listener wrote:
>
> > Hey, wait a minute! Isn't that the same Dr. Golomb who is a paid shill for
> > the statin industry??? Did you see that study she did that showed statins
> > lowered blood pressure? Who would believe her?
>
>
> I never said that about her, I said it about YOU.
>
> Susan
Hey Susan go light on listener . He may not only shilling but
ingesting too.
Bill
--
Garden in shade zone 5 S Jersey USA
In article <679mccF2nn9h7U1@mid.individual . net >,
Susan <nevermind@nomail . com > wrote:
> x-no-archive: yes
>
> listener wrote:
>
> > Hey, wait a minute! Isn't that the same Dr. Golomb who is a paid shill for
> > the statin industry??? Did you see that study she did that showed statins
> > lowered blood pressure? Who would believe her?
>
>
> I never said that about her, I said it about YOU.
>
> Susan
Hey Susan go light on listener . He may not only shilling but
ingesting too.
Bill
--
Garden in shade zone 5 S Jersey USA
Re: Statins make you stupid?
Susan <nevermind@nomail . com > wrote in news:679mccF2nn9h7U1
@mid.individual . net :
> x-no-archive: yes
>
> listener wrote:
>
>> Hey, wait a minute! Isn't that the same Dr. Golomb who is a paid shill
for
>> the statin industry??? Did you see that study she did that showed
statins
>> lowered blood pressure? Who would believe her?
>
>
> I never said that about her, I said it about YOU.
>
> Susan
You certainly implied as much. You really should call her and tell her
how you feel about statins. I'm sure she'll find you interesting.
Oh well, my brief stay here has overstepped its welcome.
Ciao!
Susan <nevermind@nomail . com > wrote in news:679mccF2nn9h7U1
@mid.individual . net :
> x-no-archive: yes
>
> listener wrote:
>
>> Hey, wait a minute! Isn't that the same Dr. Golomb who is a paid shill
for
>> the statin industry??? Did you see that study she did that showed
statins
>> lowered blood pressure? Who would believe her?
>
>
> I never said that about her, I said it about YOU.
>
> Susan
You certainly implied as much. You really should call her and tell her
how you feel about statins. I'm sure she'll find you interesting.
Oh well, my brief stay here has overstepped its welcome.
Ciao!
Re: Statins make you stupid?
Regardless of all the scientifically documented info for or against the
subject matter, I have drawn my own conclusion.
Lipitor did indeed have a substantial effect on my cognitive functions.
I started on 80 mg post surgery 9/30/07. Changed to 40 mg in December.
By mid January I was having substantial short term memory lapse's, and
much general fogginess with concentration. Dr took me off Lipitor & put
me on Crestor 10 mg in Feb, and I experienced dramatic return to normal
cognitive abilities.
Regardless of all the scientifically documented info for or against the
subject matter, I have drawn my own conclusion.
Lipitor did indeed have a substantial effect on my cognitive functions.
I started on 80 mg post surgery 9/30/07. Changed to 40 mg in December.
By mid January I was having substantial short term memory lapse's, and
much general fogginess with concentration. Dr took me off Lipitor & put
me on Crestor 10 mg in Feb, and I experienced dramatic return to normal
cognitive abilities.
Re: Statins make you stupid?
newsreader <fakeid@fakeid . com > wrote in news:642dnf-
hKMwlXJLVnZ2dnUVZ_gednZ2d@comcast . com :
> Regardless of all the scientifically documented info for or against the
> subject matter, I have drawn my own conclusion.
> Lipitor did indeed have a substantial effect on my cognitive functions.
> I started on 80 mg post surgery 9/30/07. Changed to 40 mg in December.
> By mid January I was having substantial short term memory lapse's, and
> much general fogginess with concentration. Dr took me off Lipitor & put
> me on Crestor 10 mg in Feb, and I experienced dramatic return to normal
> cognitive abilities.
>
Years ago, I tried Lipitor and experienced severe calf pain within the
first two weeks and stopped immediately - went back to pravachol.
Anyway, I'm out the door. Be prepared to get blasted about Crestor. Good
luck.
L.
newsreader <fakeid@fakeid . com > wrote in news:642dnf-
hKMwlXJLVnZ2dnUVZ_gednZ2d@comcast . com :
> Regardless of all the scientifically documented info for or against the
> subject matter, I have drawn my own conclusion.
> Lipitor did indeed have a substantial effect on my cognitive functions.
> I started on 80 mg post surgery 9/30/07. Changed to 40 mg in December.
> By mid January I was having substantial short term memory lapse's, and
> much general fogginess with concentration. Dr took me off Lipitor & put
> me on Crestor 10 mg in Feb, and I experienced dramatic return to normal
> cognitive abilities.
>
Years ago, I tried Lipitor and experienced severe calf pain within the
first two weeks and stopped immediately - went back to pravachol.
Anyway, I'm out the door. Be prepared to get blasted about Crestor. Good
luck.
L.
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