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Whoopsies Cured Another One
Whoopsies Cured Another One
"Complete recovery after iron chelation in aplastic anemia"
Park SJ, Han CW
Complete hematopoietic recovery after continuous iron chelation
therapy in a patient with severe aplastic anemia with secondary
hemochromatosis. [Journal Article]
J Korean Med Sci 2008 Apr; 23(2):320-3.
A 16-yr-old male patient with hemochromatosis due to multiple packed
red blood cell transfusions was referred to our emergency center for
the treatment of severe aplastic anemia and dyspnea. He was diagnosed
with aplastic anemia at 11-yr of age. He had received continuous
transfusions because an HLA-matched marrow donor was unavailable.
Following a continuous, approximately 5-yr transfusion, he was noted
to develop hemochromatosis. He had a dilated cardiomyopathy and
required diuretics and digitalis, multiple endocrine and liver
dysfunction, generalized bleeding, and skin pigmentation. A total
volume of red blood cell transfusion before deferoxamine therapy was
about 96,000 mL. He received a regular iron chelation therapy
(continuous intravenous infusion of deferoxamine, 50 mg/kg/day for 5
days q 3-4 weeks) for approximately seven years after the onset of
multiple organ failures. His cytopenia and organ dysfunctions began to
be gradually recovered since about 2002, following a 4-yr deferoxamine
treatment. He showed completely normal ranges of peripheral blood cell
counts, heart size, and liver function two years ago. He has not
received any transfusions for the last four years. This finding
suggests that a continuous deferoxamine infusion may play a role in
the immune regulation in addition to iron chelation effect.
Journal of Korean medical science [J Korean Med Sci]
--------------------------------------------------------------------------------
More from this journal
Who loves ya.
Tom
Jesus Was A Vegetarian!
* tinyurl . com /2r2nkh
Man Is A Herbivore!
* tinyurl . com /a3cc3
DEAD PEOPLE WALKING
* tinyurl . com /zk9fk
"Complete recovery after iron chelation in aplastic anemia"
Park SJ, Han CW
Complete hematopoietic recovery after continuous iron chelation
therapy in a patient with severe aplastic anemia with secondary
hemochromatosis. [Journal Article]
J Korean Med Sci 2008 Apr; 23(2):320-3.
A 16-yr-old male patient with hemochromatosis due to multiple packed
red blood cell transfusions was referred to our emergency center for
the treatment of severe aplastic anemia and dyspnea. He was diagnosed
with aplastic anemia at 11-yr of age. He had received continuous
transfusions because an HLA-matched marrow donor was unavailable.
Following a continuous, approximately 5-yr transfusion, he was noted
to develop hemochromatosis. He had a dilated cardiomyopathy and
required diuretics and digitalis, multiple endocrine and liver
dysfunction, generalized bleeding, and skin pigmentation. A total
volume of red blood cell transfusion before deferoxamine therapy was
about 96,000 mL. He received a regular iron chelation therapy
(continuous intravenous infusion of deferoxamine, 50 mg/kg/day for 5
days q 3-4 weeks) for approximately seven years after the onset of
multiple organ failures. His cytopenia and organ dysfunctions began to
be gradually recovered since about 2002, following a 4-yr deferoxamine
treatment. He showed completely normal ranges of peripheral blood cell
counts, heart size, and liver function two years ago. He has not
received any transfusions for the last four years. This finding
suggests that a continuous deferoxamine infusion may play a role in
the immune regulation in addition to iron chelation effect.
Journal of Korean medical science [J Korean Med Sci]
--------------------------------------------------------------------------------
More from this journal
Who loves ya.
Tom
Jesus Was A Vegetarian!
* tinyurl . com /2r2nkh
Man Is A Herbivore!
* tinyurl . com /a3cc3
DEAD PEOPLE WALKING
* tinyurl . com /zk9fk
Re: Whoopsies Cured Another One
On Apr 26, 7:25 am, "ironjust...@aol . com " <ironjust...@aol . com >
wrote:continuous, approximately 5-yr transfusion <<
One could calculate how much donated blood these .. people .. are
throwing to the wind .. to line their pockets.
They get paid for every transfusion of **donated** blood.
Cured the patient by targeting the .. iron.
Who loves ya.
Tom
Jesus Was A Vegetarian!
* tinyurl . com /2r2nkh
Man Is A Herbivore!
* tinyurl . com /a3cc3
DEAD PEOPLE WALKING
* tinyurl . com /zk9fk
> "Complete recovery after iron chelation in aplastic anemia"
>
> Park SJ, Han CW
> Complete hematopoietic recovery after continuous iron chelation
> therapy in a patient with severe aplastic anemia with secondary
> hemochromatosis. [Journal Article]
> J Korean Med Sci 2008 Apr; 23(2):320-3.
>
> A 16-yr-old male patient with hemochromatosis due to multiple packed
> red blood cell transfusions was referred to our emergency center for
> the treatment of severe aplastic anemia and dyspnea. He was diagnosed
> with aplastic anemia at 11-yr of age. He had received continuous
> transfusions because an HLA-matched marrow donor was unavailable.
> Following a continuous, approximately 5-yr transfusion, he was noted
> to develop hemochromatosis. He had a dilated cardiomyopathy and
> required diuretics and digitalis, multiple endocrine and liver
> dysfunction, generalized bleeding, and skin pigmentation. A total
> volume of red blood cell transfusion before deferoxamine therapy was
> about 96,000 mL. He received a regular iron chelation therapy
> (continuous intravenous infusion of deferoxamine, 50 mg/kg/day for 5
> days q 3-4 weeks) for approximately seven years after the onset of
> multiple organ failures. His cytopenia and organ dysfunctions began to
> be gradually recovered since about 2002, following a 4-yr deferoxamine
> treatment. He showed completely normal ranges of peripheral blood cell
> counts, heart size, and liver function two years ago. He has not
> received any transfusions for the last four years. This finding
> suggests that a continuous deferoxamine infusion may play a role in
> the immune regulation in addition to iron chelation effect.
> Journal of Korean medical science [J Korean Med Sci]
> --------------------------------------------------------------------------=
------
> More from this journal
>
> Who loves ya.
> Tom
>
> Jesus Was A Vegetarian! * tinyurl . com /2r2nkh
>
> Man Is A Herbivore! * tinyurl . com /a3cc3
>
> DEAD PEOPLE WALKING * tinyurl . com /zk9fk
On Apr 26, 7:25 am, "ironjust...@aol . com " <ironjust...@aol . com >
wrote:continuous, approximately 5-yr transfusion <<
One could calculate how much donated blood these .. people .. are
throwing to the wind .. to line their pockets.
They get paid for every transfusion of **donated** blood.
Cured the patient by targeting the .. iron.
Who loves ya.
Tom
Jesus Was A Vegetarian!
* tinyurl . com /2r2nkh
Man Is A Herbivore!
* tinyurl . com /a3cc3
DEAD PEOPLE WALKING
* tinyurl . com /zk9fk
> "Complete recovery after iron chelation in aplastic anemia"
>
> Park SJ, Han CW
> Complete hematopoietic recovery after continuous iron chelation
> therapy in a patient with severe aplastic anemia with secondary
> hemochromatosis. [Journal Article]
> J Korean Med Sci 2008 Apr; 23(2):320-3.
>
> A 16-yr-old male patient with hemochromatosis due to multiple packed
> red blood cell transfusions was referred to our emergency center for
> the treatment of severe aplastic anemia and dyspnea. He was diagnosed
> with aplastic anemia at 11-yr of age. He had received continuous
> transfusions because an HLA-matched marrow donor was unavailable.
> Following a continuous, approximately 5-yr transfusion, he was noted
> to develop hemochromatosis. He had a dilated cardiomyopathy and
> required diuretics and digitalis, multiple endocrine and liver
> dysfunction, generalized bleeding, and skin pigmentation. A total
> volume of red blood cell transfusion before deferoxamine therapy was
> about 96,000 mL. He received a regular iron chelation therapy
> (continuous intravenous infusion of deferoxamine, 50 mg/kg/day for 5
> days q 3-4 weeks) for approximately seven years after the onset of
> multiple organ failures. His cytopenia and organ dysfunctions began to
> be gradually recovered since about 2002, following a 4-yr deferoxamine
> treatment. He showed completely normal ranges of peripheral blood cell
> counts, heart size, and liver function two years ago. He has not
> received any transfusions for the last four years. This finding
> suggests that a continuous deferoxamine infusion may play a role in
> the immune regulation in addition to iron chelation effect.
> Journal of Korean medical science [J Korean Med Sci]
> --------------------------------------------------------------------------=
------
> More from this journal
>
> Who loves ya.
> Tom
>
> Jesus Was A Vegetarian! * tinyurl . com /2r2nkh
>
> Man Is A Herbivore! * tinyurl . com /a3cc3
>
> DEAD PEOPLE WALKING * tinyurl . com /zk9fk
Re: Whoopsies Cured Another One
On Apr 26, 8:31 am, ironjustice <teamtan...@hotmail . com > wrote:
Aplastic
anemia <<
* en.wikipedia.org/wiki/Aplastic anemia
Treating aplastic anemia involves suppression of the immune system, an
effect achieved by daily medicine intake, or, in more severe cases, a
bone marrow transplant, a potential cure but a risky procedure.[1] The
transplanted bone marrow replaces the failing bone marrow cells with
new ones from a matching donor. The pluripotent stem cells in the bone
marrow reconstitute all three blood cell lines, giving the patient a
new immune system, red blood cells, and platelets. However, besides
the risk of graft failure, there is also a risk that the newly created
white blood cells may attack the rest of the body ("graft-versus-host
disease").
Medical therapy of aplastic anemia often includes a short course of
anti-thymocyte globulin (ATG) or anti-lymphocyte globulin (ALG) and
several months of treatment with cyclosporin to modulate the immune
system. Mild chemotherapy with agents such as cyclophosphamide and
vincristine may also be effective. Antibodies therapy, such as ATG,
targets T-cells, which are believed to attack the bone marrow.
Steroids are generally ineffective.
In the past, before the above treatments became available, patients
with low leukocyte counts were often confined to a sterile room or
bubble (to reduce risk of infections), as in the famed case of Ted
DeVita.[2]
Who loves ya.
Tom
Jesus Was A Vegetarian!
* tinyurl . com /2r2nkh
Man Is A Herbivore!
* tinyurl . com /a3cc3
DEAD PEOPLE WALKING
* tinyurl . com /zk9fk
> On Apr 26, 7:25 am, "ironjust...@aol . com " <ironjust...@aol . com >
> wrote:continuous, approximately 5-yr transfusion <<
>
> One could calculate how much donated blood these .. people .. are
> throwing to the wind .. to line their pockets.
> They get paid for every transfusion of **donated** blood.
>
> Cured the patient by targeting the .. iron.
>
> Who loves ya.
> Tom
>
> Jesus Was A Vegetarian! * tinyurl . com /2r2nkh
>
> Man Is A Herbivore! * tinyurl . com /a3cc3
>
> DEAD PEOPLE WALKING * tinyurl . com /zk9fk
>
>
>
> > "Complete recovery after iron chelation in aplastic anemia"
>
> > Park SJ, Han CW
> > Complete hematopoietic recovery after continuous iron chelation
> > therapy in a patient with severe aplastic anemia with secondary
> > hemochromatosis. [Journal Article]
> > J Korean Med Sci 2008 Apr; 23(2):320-3.
>
> > A 16-yr-old male patient with hemochromatosis due to multiple packed
> > red blood cell transfusions was referred to our emergency center for
> > the treatment of severe aplastic anemia and dyspnea. He was diagnosed
> > with aplastic anemia at 11-yr of age. He had received continuous
> > transfusions because an HLA-matched marrow donor was unavailable.
> > Following a continuous, approximately 5-yr transfusion, he was noted
> > to develop hemochromatosis. He had a dilated cardiomyopathy and
> > required diuretics and digitalis, multiple endocrine and liver
> > dysfunction, generalized bleeding, and skin pigmentation. A total
> > volume of red blood cell transfusion before deferoxamine therapy was
> > about 96,000 mL. He received a regular iron chelation therapy
> > (continuous intravenous infusion of deferoxamine, 50 mg/kg/day for 5
> > days q 3-4 weeks) for approximately seven years after the onset of
> > multiple organ failures. His cytopenia and organ dysfunctions began to
> > be gradually recovered since about 2002, following a 4-yr deferoxamine
> > treatment. He showed completely normal ranges of peripheral blood cell
> > counts, heart size, and liver function two years ago. He has not
> > received any transfusions for the last four years. This finding
> > suggests that a continuous deferoxamine infusion may play a role in
> > the immune regulation in addition to iron chelation effect.
> > Journal of Korean medical science [J Korean Med Sci]
> > ------------------------------------------------------------------------=
--------
> > More from this journal
>
> > Who loves ya.
> > Tom
>
> > Jesus Was A Vegetarian! * tinyurl . com /2r2nkh
>
> > Man Is A Herbivore! * tinyurl . com /a3cc3
>
> > DEAD PEOPLE WALKING * tinyurl . com /zk9fk- Hide quoted text -
>
> - Show quoted text -
On Apr 26, 8:31 am, ironjustice <teamtan...@hotmail . com > wrote:
Aplastic
anemia <<
* en.wikipedia.org/wiki/Aplastic anemia
Treating aplastic anemia involves suppression of the immune system, an
effect achieved by daily medicine intake, or, in more severe cases, a
bone marrow transplant, a potential cure but a risky procedure.[1] The
transplanted bone marrow replaces the failing bone marrow cells with
new ones from a matching donor. The pluripotent stem cells in the bone
marrow reconstitute all three blood cell lines, giving the patient a
new immune system, red blood cells, and platelets. However, besides
the risk of graft failure, there is also a risk that the newly created
white blood cells may attack the rest of the body ("graft-versus-host
disease").
Medical therapy of aplastic anemia often includes a short course of
anti-thymocyte globulin (ATG) or anti-lymphocyte globulin (ALG) and
several months of treatment with cyclosporin to modulate the immune
system. Mild chemotherapy with agents such as cyclophosphamide and
vincristine may also be effective. Antibodies therapy, such as ATG,
targets T-cells, which are believed to attack the bone marrow.
Steroids are generally ineffective.
In the past, before the above treatments became available, patients
with low leukocyte counts were often confined to a sterile room or
bubble (to reduce risk of infections), as in the famed case of Ted
DeVita.[2]
Who loves ya.
Tom
Jesus Was A Vegetarian!
* tinyurl . com /2r2nkh
Man Is A Herbivore!
* tinyurl . com /a3cc3
DEAD PEOPLE WALKING
* tinyurl . com /zk9fk
> On Apr 26, 7:25 am, "ironjust...@aol . com " <ironjust...@aol . com >
> wrote:continuous, approximately 5-yr transfusion <<
>
> One could calculate how much donated blood these .. people .. are
> throwing to the wind .. to line their pockets.
> They get paid for every transfusion of **donated** blood.
>
> Cured the patient by targeting the .. iron.
>
> Who loves ya.
> Tom
>
> Jesus Was A Vegetarian! * tinyurl . com /2r2nkh
>
> Man Is A Herbivore! * tinyurl . com /a3cc3
>
> DEAD PEOPLE WALKING * tinyurl . com /zk9fk
>
>
>
> > "Complete recovery after iron chelation in aplastic anemia"
>
> > Park SJ, Han CW
> > Complete hematopoietic recovery after continuous iron chelation
> > therapy in a patient with severe aplastic anemia with secondary
> > hemochromatosis. [Journal Article]
> > J Korean Med Sci 2008 Apr; 23(2):320-3.
>
> > A 16-yr-old male patient with hemochromatosis due to multiple packed
> > red blood cell transfusions was referred to our emergency center for
> > the treatment of severe aplastic anemia and dyspnea. He was diagnosed
> > with aplastic anemia at 11-yr of age. He had received continuous
> > transfusions because an HLA-matched marrow donor was unavailable.
> > Following a continuous, approximately 5-yr transfusion, he was noted
> > to develop hemochromatosis. He had a dilated cardiomyopathy and
> > required diuretics and digitalis, multiple endocrine and liver
> > dysfunction, generalized bleeding, and skin pigmentation. A total
> > volume of red blood cell transfusion before deferoxamine therapy was
> > about 96,000 mL. He received a regular iron chelation therapy
> > (continuous intravenous infusion of deferoxamine, 50 mg/kg/day for 5
> > days q 3-4 weeks) for approximately seven years after the onset of
> > multiple organ failures. His cytopenia and organ dysfunctions began to
> > be gradually recovered since about 2002, following a 4-yr deferoxamine
> > treatment. He showed completely normal ranges of peripheral blood cell
> > counts, heart size, and liver function two years ago. He has not
> > received any transfusions for the last four years. This finding
> > suggests that a continuous deferoxamine infusion may play a role in
> > the immune regulation in addition to iron chelation effect.
> > Journal of Korean medical science [J Korean Med Sci]
> > ------------------------------------------------------------------------=
--------
> > More from this journal
>
> > Who loves ya.
> > Tom
>
> > Jesus Was A Vegetarian! * tinyurl . com /2r2nkh
>
> > Man Is A Herbivore! * tinyurl . com /a3cc3
>
> > DEAD PEOPLE WALKING * tinyurl . com /zk9fk- Hide quoted text -
>
> - Show quoted text -
Re: Whoopsies Cured Another One
On Apr 26, 9:17 am, ironjustice <teamtan...@hotmail . com >
wrote:Aplastic
anemia <<
Hip surgery .. ?
"These observations are an encouragement to attempt treatment by
repeated phlebotomies"
Joint Bone Spine 2000;67(3):171-7
Phlebotomy: a treatment of ischaemic necrosis of the femoral head?
Analysis of a hypothesis.
Bouteiller G
Service de rhumatologie, center hosptialier, Auch, France.
The treatment of non-traumatic ischaemic osteonecrosis of the femoral
head (ONFH) remains problematical and there is evidently scope to seek
for a medical treatment of this disease which often leads to a
surgical procedure for hip prosthesis.
If we exclude the context of hemoglobin disorders, necrosis appears
mainly in adults, when their limb bones contain a fatty marrow.
Investigations such as intramedullary pressure measurement and
transosseous phlebography suggest a disorder of the intraosseous blood
circulation.
Various studies in animals and man have provided arguments indicating
that a kind of intraosseous 'obesity' due to hyperplasia and/or
hypertrophy of the fatty tissue of the femoral marrow play a role in
the development of necrosis.
In this respect, the blood flow of the yellow marrow is close to
ischemia, whereas red marrow flow can be very high.
In various conditions, mainly hemolytic anemias, the
femoral yellow marrow can convert to red marrow, which has also been
described in anemias induced by blood loss. If it is not thought
unreasonable to consider
ONFH an 'ischemic' disease, these observations are an encouragement to
attempt treatment by repeated phlebotomies. This procedure may locally
restore red marrow, and then an adequate blood flow which could
stabilize or even reverse
the lesions if they are diagnosed early.
Publication Types:
Review
Review, tutorial
PMID: 10875313, UI: 20331568
----------------------
Orban H, Cîrstoiu C, Adam R
Total hip arthroplasty in secondary systemic lupus erythematosus
femoral head avascular necrosis. [Journal Article]
Rom J Intern Med 2007; 45(1):123-9.
Systemic lupus erythematosus is a multisystem disease with a large
spectrum of clinical manifestations and a variable course.
Lupus is marked by both humoral and cellular immunologic
abnormalities, including multiple auto-antibodies especially anti DNA
antibodies.
Epidemiology - female predominance, occurring usually between second
and fourth decade of life, more frequently in hispanic and black
patients.
Family predominance has been noticed.
Provocative agents - ultraviolet light, viral infections, drugs and
situational stresses.
Pathogenesis - pathological features can affect a large spectrum of
internal organs and systems - osteoarticulary injuries, skin rash,
lymphadenopathy, glomerulonephritis, myocarditis, digestive system
lesions.
Musculo skeletal abnormalities include migratory arthritis, effusion
and stiffness in small and large joints.
Articular erosions are uncommon.
Skeletal abnormalities include osteopenia and osteonecrosis, due to
two pathological mechanisms: vasculitis and long term corticotherapy.
Fifteen to twenty percent of SLE patients are affected by femoral head
avascular necrosis (FHAN).
Diagnosis rests on clinical signs - hip pain, limited range of motion,
walking with a limp.; radiological findings - best grouped in Arlet-
Ficat standing system; MRI - high sensitivity, especially in
infraradiological stages.
Treatment - in incipient stages core decompression represents the best
therapeutical option.
In advanced, arthritis stages, total hip arthroplasty (THA) is the
standart treatment.
Three implant types are available: bipolar, uncemented and cemented.
An increased number of cotyloidites occurred after bipolar implants.
Emphasised osteopenia and excessive bleeding represent
contraindications for uncemented implants.
Considering all of this, cemented implants are considered, the right
choice, methacrylate cement providing strong and durable fixation of
THA implants to bone.
No meaningful differences were observed in postoperative functional
recovery between LSE patients and other etiology FHAN patients.
----------------------------------------------------------------------------=
----
Romanian journal of internal medicine = Revue roumaine de médecine
interne [Rom J Intern Med]
Who loves ya.
Tom
Jesus Was A Vegetarian!
* tinyurl . com /2r2nkh
Man Is A Herbivore!
* tinyurl . com /a3cc3
DEAD PEOPLE WALKING
* tinyurl . com /zk9fk
> On Apr 26, 8:31 am, ironjustice <teamtan...@hotmail . com > wrote:
> Aplastic
> anemia <<
>
> * en.wikipedia.org/wiki/Aplastic anemia
>
> Treating aplastic anemia involves suppression of the immune system, an
> effect achieved by daily medicine intake, or, in more severe cases, a
> bone marrow transplant, a potential cure but a risky procedure.[1] The
> transplanted bone marrow replaces the failing bone marrow cells with
> new ones from a matching donor. The pluripotent stem cells in the bone
> marrow reconstitute all three blood cell lines, giving the patient a
> new immune system, red blood cells, and platelets. However, besides
> the risk of graft failure, there is also a risk that the newly created
> white blood cells may attack the rest of the body ("graft-versus-host
> disease").
>
> Medical therapy of aplastic anemia often includes a short course of
> anti-thymocyte globulin (ATG) or anti-lymphocyte globulin (ALG) and
> several months of treatment with cyclosporin to modulate the immune
> system. Mild chemotherapy with agents such as cyclophosphamide and
> vincristine may also be effective. Antibodies therapy, such as ATG,
> targets T-cells, which are believed to attack the bone marrow.
> Steroids are generally ineffective.
>
> In the past, before the above treatments became available, patients
> with low leukocyte counts were often confined to a sterile room or
> bubble (to reduce risk of infections), as in the famed case of Ted
> DeVita.[2]
>
> Who loves ya.
> Tom
>
> Jesus Was A Vegetarian! * tinyurl . com /2r2nkh
>
> Man Is A Herbivore! * tinyurl . com /a3cc3
>
> DEAD PEOPLE WALKING * tinyurl . com /zk9fk
>
>
>
> > On Apr 26, 7:25 am, "ironjust...@aol . com " <ironjust...@aol . com >
> > wrote:continuous, approximately 5-yr transfusion <<
>
> > One could calculate how much donated blood these .. people .. are
> > throwing to the wind .. to line their pockets.
> > They get paid for every transfusion of **donated** blood.
>
> > Cured the patient by targeting the .. iron.
>
> > Who loves ya.
> > Tom
>
> > Jesus Was A Vegetarian! * tinyurl . com /2r2nkh
>
> > Man Is A Herbivore! * tinyurl . com /a3cc3
>
> > DEAD PEOPLE WALKING * tinyurl . com /zk9fk
>
> > > "Complete recovery after iron chelation in aplastic anemia"
>
> > > Park SJ, Han CW
> > > Complete hematopoietic recovery after continuous iron chelation
> > > therapy in a patient with severe aplastic anemia with secondary
> > > hemochromatosis. [Journal Article]
> > > J Korean Med Sci 2008 Apr; 23(2):320-3.
>
> > > A 16-yr-old male patient with hemochromatosis due to multiple packed
> > > red blood cell transfusions was referred to our emergency center for
> > > the treatment of severe aplastic anemia and dyspnea. He was diagnosed
> > > with aplastic anemia at 11-yr of age. He had received continuous
> > > transfusions because an HLA-matched marrow donor was unavailable.
> > > Following a continuous, approximately 5-yr transfusion, he was noted
> > > to develop hemochromatosis. He had a dilated cardiomyopathy and
> > > required diuretics and digitalis, multiple endocrine and liver
> > > dysfunction, generalized bleeding, and skin pigmentation. A total
> > > volume of red blood cell transfusion before deferoxamine therapy was
> > > about 96,000 mL. He received a regular iron chelation therapy
> > > (continuous intravenous infusion of deferoxamine, 50 mg/kg/day for 5
> > > days q 3-4 weeks) for approximately seven years after the onset of
> > > multiple organ failures. His cytopenia and organ dysfunctions began to=
> > > be gradually recovered since about 2002, following a 4-yr deferoxamine=
> > > treatment. He showed completely normal ranges of peripheral blood cell=
> > > counts, heart size, and liver function two years ago. He has not
> > > received any transfusions for the last four years. This finding
> > > suggests that a continuous deferoxamine infusion may play a role in
> > > the immune regulation in addition to iron chelation effect.
> > > Journal of Korean medical science [J Korean Med Sci]
> > > ----------------------------------------------------------------------=
----------
> > > More from this journal
>
> > > Who loves ya.
> > > Tom
>
> > > Jesus Was A Vegetarian! * tinyurl . com /2r2nkh
>
> > > Man Is A Herbivore! * tinyurl . com /a3cc3
>
> > > DEAD PEOPLE WALKING * tinyurl . com /zk9fk-Hide quoted text -
>
> > - Show quoted text -- Hide quoted text -
>
> - Show quoted text -
On Apr 26, 9:17 am, ironjustice <teamtan...@hotmail . com >
wrote:Aplastic
anemia <<
Hip surgery .. ?
"These observations are an encouragement to attempt treatment by
repeated phlebotomies"
Joint Bone Spine 2000;67(3):171-7
Phlebotomy: a treatment of ischaemic necrosis of the femoral head?
Analysis of a hypothesis.
Bouteiller G
Service de rhumatologie, center hosptialier, Auch, France.
The treatment of non-traumatic ischaemic osteonecrosis of the femoral
head (ONFH) remains problematical and there is evidently scope to seek
for a medical treatment of this disease which often leads to a
surgical procedure for hip prosthesis.
If we exclude the context of hemoglobin disorders, necrosis appears
mainly in adults, when their limb bones contain a fatty marrow.
Investigations such as intramedullary pressure measurement and
transosseous phlebography suggest a disorder of the intraosseous blood
circulation.
Various studies in animals and man have provided arguments indicating
that a kind of intraosseous 'obesity' due to hyperplasia and/or
hypertrophy of the fatty tissue of the femoral marrow play a role in
the development of necrosis.
In this respect, the blood flow of the yellow marrow is close to
ischemia, whereas red marrow flow can be very high.
In various conditions, mainly hemolytic anemias, the
femoral yellow marrow can convert to red marrow, which has also been
described in anemias induced by blood loss. If it is not thought
unreasonable to consider
ONFH an 'ischemic' disease, these observations are an encouragement to
attempt treatment by repeated phlebotomies. This procedure may locally
restore red marrow, and then an adequate blood flow which could
stabilize or even reverse
the lesions if they are diagnosed early.
Publication Types:
Review
Review, tutorial
PMID: 10875313, UI: 20331568
----------------------
Orban H, Cîrstoiu C, Adam R
Total hip arthroplasty in secondary systemic lupus erythematosus
femoral head avascular necrosis. [Journal Article]
Rom J Intern Med 2007; 45(1):123-9.
Systemic lupus erythematosus is a multisystem disease with a large
spectrum of clinical manifestations and a variable course.
Lupus is marked by both humoral and cellular immunologic
abnormalities, including multiple auto-antibodies especially anti DNA
antibodies.
Epidemiology - female predominance, occurring usually between second
and fourth decade of life, more frequently in hispanic and black
patients.
Family predominance has been noticed.
Provocative agents - ultraviolet light, viral infections, drugs and
situational stresses.
Pathogenesis - pathological features can affect a large spectrum of
internal organs and systems - osteoarticulary injuries, skin rash,
lymphadenopathy, glomerulonephritis, myocarditis, digestive system
lesions.
Musculo skeletal abnormalities include migratory arthritis, effusion
and stiffness in small and large joints.
Articular erosions are uncommon.
Skeletal abnormalities include osteopenia and osteonecrosis, due to
two pathological mechanisms: vasculitis and long term corticotherapy.
Fifteen to twenty percent of SLE patients are affected by femoral head
avascular necrosis (FHAN).
Diagnosis rests on clinical signs - hip pain, limited range of motion,
walking with a limp.; radiological findings - best grouped in Arlet-
Ficat standing system; MRI - high sensitivity, especially in
infraradiological stages.
Treatment - in incipient stages core decompression represents the best
therapeutical option.
In advanced, arthritis stages, total hip arthroplasty (THA) is the
standart treatment.
Three implant types are available: bipolar, uncemented and cemented.
An increased number of cotyloidites occurred after bipolar implants.
Emphasised osteopenia and excessive bleeding represent
contraindications for uncemented implants.
Considering all of this, cemented implants are considered, the right
choice, methacrylate cement providing strong and durable fixation of
THA implants to bone.
No meaningful differences were observed in postoperative functional
recovery between LSE patients and other etiology FHAN patients.
----------------------------------------------------------------------------=
----
Romanian journal of internal medicine = Revue roumaine de médecine
interne [Rom J Intern Med]
Who loves ya.
Tom
Jesus Was A Vegetarian!
* tinyurl . com /2r2nkh
Man Is A Herbivore!
* tinyurl . com /a3cc3
DEAD PEOPLE WALKING
* tinyurl . com /zk9fk
> On Apr 26, 8:31 am, ironjustice <teamtan...@hotmail . com > wrote:
> Aplastic
> anemia <<
>
> * en.wikipedia.org/wiki/Aplastic anemia
>
> Treating aplastic anemia involves suppression of the immune system, an
> effect achieved by daily medicine intake, or, in more severe cases, a
> bone marrow transplant, a potential cure but a risky procedure.[1] The
> transplanted bone marrow replaces the failing bone marrow cells with
> new ones from a matching donor. The pluripotent stem cells in the bone
> marrow reconstitute all three blood cell lines, giving the patient a
> new immune system, red blood cells, and platelets. However, besides
> the risk of graft failure, there is also a risk that the newly created
> white blood cells may attack the rest of the body ("graft-versus-host
> disease").
>
> Medical therapy of aplastic anemia often includes a short course of
> anti-thymocyte globulin (ATG) or anti-lymphocyte globulin (ALG) and
> several months of treatment with cyclosporin to modulate the immune
> system. Mild chemotherapy with agents such as cyclophosphamide and
> vincristine may also be effective. Antibodies therapy, such as ATG,
> targets T-cells, which are believed to attack the bone marrow.
> Steroids are generally ineffective.
>
> In the past, before the above treatments became available, patients
> with low leukocyte counts were often confined to a sterile room or
> bubble (to reduce risk of infections), as in the famed case of Ted
> DeVita.[2]
>
> Who loves ya.
> Tom
>
> Jesus Was A Vegetarian! * tinyurl . com /2r2nkh
>
> Man Is A Herbivore! * tinyurl . com /a3cc3
>
> DEAD PEOPLE WALKING * tinyurl . com /zk9fk
>
>
>
> > On Apr 26, 7:25 am, "ironjust...@aol . com " <ironjust...@aol . com >
> > wrote:continuous, approximately 5-yr transfusion <<
>
> > One could calculate how much donated blood these .. people .. are
> > throwing to the wind .. to line their pockets.
> > They get paid for every transfusion of **donated** blood.
>
> > Cured the patient by targeting the .. iron.
>
> > Who loves ya.
> > Tom
>
> > Jesus Was A Vegetarian! * tinyurl . com /2r2nkh
>
> > Man Is A Herbivore! * tinyurl . com /a3cc3
>
> > DEAD PEOPLE WALKING * tinyurl . com /zk9fk
>
> > > "Complete recovery after iron chelation in aplastic anemia"
>
> > > Park SJ, Han CW
> > > Complete hematopoietic recovery after continuous iron chelation
> > > therapy in a patient with severe aplastic anemia with secondary
> > > hemochromatosis. [Journal Article]
> > > J Korean Med Sci 2008 Apr; 23(2):320-3.
>
> > > A 16-yr-old male patient with hemochromatosis due to multiple packed
> > > red blood cell transfusions was referred to our emergency center for
> > > the treatment of severe aplastic anemia and dyspnea. He was diagnosed
> > > with aplastic anemia at 11-yr of age. He had received continuous
> > > transfusions because an HLA-matched marrow donor was unavailable.
> > > Following a continuous, approximately 5-yr transfusion, he was noted
> > > to develop hemochromatosis. He had a dilated cardiomyopathy and
> > > required diuretics and digitalis, multiple endocrine and liver
> > > dysfunction, generalized bleeding, and skin pigmentation. A total
> > > volume of red blood cell transfusion before deferoxamine therapy was
> > > about 96,000 mL. He received a regular iron chelation therapy
> > > (continuous intravenous infusion of deferoxamine, 50 mg/kg/day for 5
> > > days q 3-4 weeks) for approximately seven years after the onset of
> > > multiple organ failures. His cytopenia and organ dysfunctions began to=
> > > be gradually recovered since about 2002, following a 4-yr deferoxamine=
> > > treatment. He showed completely normal ranges of peripheral blood cell=
> > > counts, heart size, and liver function two years ago. He has not
> > > received any transfusions for the last four years. This finding
> > > suggests that a continuous deferoxamine infusion may play a role in
> > > the immune regulation in addition to iron chelation effect.
> > > Journal of Korean medical science [J Korean Med Sci]
> > > ----------------------------------------------------------------------=
----------
> > > More from this journal
>
> > > Who loves ya.
> > > Tom
>
> > > Jesus Was A Vegetarian! * tinyurl . com /2r2nkh
>
> > > Man Is A Herbivore! * tinyurl . com /a3cc3
>
> > > DEAD PEOPLE WALKING * tinyurl . com /zk9fk-Hide quoted text -
>
> > - Show quoted text -- Hide quoted text -
>
> - Show quoted text -
Re: Whoopsies Cured Another One
On Apr 26, 9:28 pm, ironjustice <teamtan...@hotmail . com > wrote: to
line their pockets. <<
HAS there EVER been a study of blood donation in lupus .. ?
Anemia never killed anyone ..
You get a bit tired but it don't kill ya ..
They have noted one should not be transfused until ones hemoglobin
gets below .. 6 .. so logically one can BE "around 6" .. according to
the .. experts.
So WHAT .. would it BE to .. 'them' .. IF .. say a bunch of people got
together .. say .. and said .. "hey" .. WE .. are the study group.
Saves alot of time and money ..
I don't really know how bad lupus gets .. personally .. but I hear it
gets .. pretty .. bad ..
Sickle patients seem to be cured by keeping their hemoglobin down
around .. there .. coincidentally ..
Some people don't like to use the word .. cure .. but what really
IS .. "long term event free remission" .. ?
Who loves ya.
Tom
Jesus Was A Vegetarian!
* tinyurl . com /2r2nkh
Man Is A Herbivore!
* tinyurl . com /a3cc3
DEAD PEOPLE WALKING
* tinyurl . com /zk9fk
> On Apr 26, 9:17 am, ironjustice <teamtan...@hotmail . com >
> wrote:Aplastic
> anemia <<
>
> Hip surgery .. ?
>
> "These observations are an encouragement to attempt treatment by
> repeated phlebotomies"
>
> Joint Bone Spine 2000;67(3):171-7
>
> Phlebotomy: a treatment of ischaemic necrosis of the femoral head?
> Analysis of a hypothesis.
>
> Bouteiller G
> Service de rhumatologie, center hosptialier, Auch, France.
>
> The treatment of non-traumatic ischaemic osteonecrosis of the femoral
> head (ONFH) remains problematical and there is evidently scope to seek
> for a medical treatment of this disease which often leads to a
> surgical procedure for hip prosthesis.
> If we exclude the context of hemoglobin disorders, necrosis appears
> mainly in adults, when their limb bones contain a fatty marrow.
> Investigations such as intramedullary pressure measurement and
> transosseous phlebography suggest a disorder of the intraosseous blood
> circulation.
> Various studies in animals and man have provided arguments indicating
> that a kind of intraosseous 'obesity' due to hyperplasia and/or
> hypertrophy of the fatty tissue of the femoral marrow play a role in
> the development of necrosis.
> In this respect, the blood flow of the yellow marrow is close to
> ischemia, whereas red marrow flow can be very high.
> In various conditions, mainly hemolytic anemias, the
> femoral yellow marrow can convert to red marrow, which has also been
> described in anemias induced by blood loss. If it is not thought
> unreasonable to consider
> ONFH an 'ischemic' disease, these observations are an encouragement to
> attempt treatment by repeated phlebotomies. This procedure may locally
> restore red marrow, and then an adequate blood flow which could
> stabilize or even reverse
> the lesions if they are diagnosed early.
>
> Publication Types:
>
> Review
> Review, tutorial
> PMID: 10875313, UI: 20331568
>
> ----------------------
>
> Orban H, Cîrstoiu C, Adam R
> Total hip arthroplasty in secondary systemic lupus erythematosus
> femoral head avascular necrosis. [Journal Article]
> Rom J Intern Med 2007; 45(1):123-9.
>
> Systemic lupus erythematosus is a multisystem disease with a large
> spectrum of clinical manifestations and a variable course.
> Lupus is marked by both humoral and cellular immunologic
> abnormalities, including multiple auto-antibodies especially anti DNA
> antibodies.
> Epidemiology - female predominance, occurring usually between second
> and fourth decade of life, more frequently in hispanic and black
> patients.
> Family predominance has been noticed.
> Provocative agents - ultraviolet light, viral infections, drugs and
> situational stresses.
> Pathogenesis - pathological features can affect a large spectrum of
> internal organs and systems - osteoarticulary injuries, skin rash,
> lymphadenopathy, glomerulonephritis, myocarditis, digestive system
> lesions.
> Musculo skeletal abnormalities include migratory arthritis, effusion
> and stiffness in small and large joints.
> Articular erosions are uncommon.
> Skeletal abnormalities include osteopenia and osteonecrosis, due to
> two pathological mechanisms: vasculitis and long term corticotherapy.
> Fifteen to twenty percent of SLE patients are affected by femoral head
> avascular necrosis (FHAN).
> Diagnosis rests on clinical signs - hip pain, limited range of motion,
> walking with a limp.; radiological findings - best grouped in Arlet-
> Ficat standing system; MRI - high sensitivity, especially in
> infraradiological stages.
> Treatment - in incipient stages core decompression represents the best
> therapeutical option.
> In advanced, arthritis stages, total hip arthroplasty (THA) is the
> standart treatment.
> Three implant types are available: bipolar, uncemented and cemented.
> An increased number of cotyloidites occurred after bipolar implants.
> Emphasised osteopenia and excessive bleeding represent
> contraindications for uncemented implants.
> Considering all of this, cemented implants are considered, the right
> choice, methacrylate cement providing strong and durable fixation of
> THA implants to bone.
> No meaningful differences were observed in postoperative functional
> recovery between LSE patients and other etiology FHAN patients.
> --------------------------------------------------------------------------=
------
> Romanian journal of internal medicine = Revue roumaine de médecine
> interne [Rom J Intern Med]
>
> Who loves ya.
> Tom
>
> Jesus Was A Vegetarian! * tinyurl . com /2r2nkh
>
> Man Is A Herbivore! * tinyurl . com /a3cc3
>
> DEAD PEOPLE WALKING * tinyurl . com /zk9fk
>
>
>
> > On Apr 26, 8:31 am, ironjustice <teamtan...@hotmail . com > wrote:
> > Aplastic
> > anemia <<
>
> > * en.wikipedia.org/wiki/Aplastic anemia
>
> > Treating aplastic anemia involves suppression of the immune system, an
> > effect achieved by daily medicine intake, or, in more severe cases, a
> > bone marrow transplant, a potential cure but a risky procedure.[1] The
> > transplanted bone marrow replaces the failing bone marrow cells with
> > new ones from a matching donor. The pluripotent stem cells in the bone
> > marrow reconstitute all three blood cell lines, giving the patient a
> > new immune system, red blood cells, and platelets. However, besides
> > the risk of graft failure, there is also a risk that the newly created
> > white blood cells may attack the rest of the body ("graft-versus-host
> > disease").
>
> > Medical therapy of aplastic anemia often includes a short course of
> > anti-thymocyte globulin (ATG) or anti-lymphocyte globulin (ALG) and
> > several months of treatment with cyclosporin to modulate the immune
> > system. Mild chemotherapy with agents such as cyclophosphamide and
> > vincristine may also be effective. Antibodies therapy, such as ATG,
> > targets T-cells, which are believed to attack the bone marrow.
> > Steroids are generally ineffective.
>
> > In the past, before the above treatments became available, patients
> > with low leukocyte counts were often confined to a sterile room or
> > bubble (to reduce risk of infections), as in the famed case of Ted
> > DeVita.[2]
>
> > Who loves ya.
> > Tom
>
> > Jesus Was A Vegetarian! * tinyurl . com /2r2nkh
>
> > Man Is A Herbivore! * tinyurl . com /a3cc3
>
> > DEAD PEOPLE WALKING * tinyurl . com /zk9fk
>
> > > On Apr 26, 7:25 am, "ironjust...@aol . com " <ironjust...@aol . com >
> > > wrote:continuous, approximately 5-yr transfusion <<
>
> > > One could calculate how much donated blood these .. people .. are
> > > throwing to the wind .. to line their pockets.
> > > They get paid for every transfusion of **donated** blood.
>
> > > Cured the patient by targeting the .. iron.
>
> > > Who loves ya.
> > > Tom
>
> > > Jesus Was A Vegetarian! * tinyurl . com /2r2nkh
>
> > > Man Is A Herbivore! * tinyurl . com /a3cc3
>
> > > DEAD PEOPLE WALKING * tinyurl . com /zk9fk
>
> > > > "Complete recovery after iron chelation in aplastic anemia"
>
> > > > Park SJ, Han CW
> > > > Complete hematopoietic recovery after continuous iron chelation
> > > > therapy in a patient with severe aplastic anemia with secondary
> > > > hemochromatosis. [Journal Article]
> > > > J Korean Med Sci 2008 Apr; 23(2):320-3.
>
> > > > A 16-yr-old male patient with hemochromatosis due to multiple packed=
> > > > red blood cell transfusions was referred to our emergency center for=
> > > > the treatment of severe aplastic anemia and dyspnea. He was diagnose=
d
> > > > with aplastic anemia at 11-yr of age. He had received continuous
> > > > transfusions because an HLA-matched marrow donor was unavailable.
> > > > Following a continuous, approximately 5-yr transfusion, he was noted=
> > > > to develop hemochromatosis. He had a dilated cardiomyopathy and
> > > > required diuretics and digitalis, multiple endocrine and liver
> > > > dysfunction, generalized bleeding, and skin pigmentation. A total
> > > > volume of red blood cell transfusion before deferoxamine therapy was=
> > > > about 96,000 mL. He received a regular iron chelation therapy
> > > > (continuous intravenous infusion of deferoxamine, 50 mg/kg/day for 5=
> > > > days q 3-4 weeks) for approximately seven years after the onset of
> > > > multiple organ failures. His cytopenia and organ dysfunctions began =
to
> > > > be gradually recovered since about 2002, following a 4-yr deferoxami=
ne
> > > > treatment. He showed completely normal ranges of peripheral blood ce=
ll
> > > > counts, heart size, and liver function two years ago. He has not
> > > > received any transfusions for the last four years. This finding
> > > > suggests that a continuous deferoxamine infusion may play a role in
> > > > the immune regulation in addition to iron chelation effect.
> > > > Journal of Korean medical science [J Korean Med Sci]
> > > > --------------------------------------------------------------------=
------------
> > > > More from this journal
>
> > > > Who loves ya.
> > > > Tom
>
> > > > Jesus Was A Vegetarian! * tinyurl . com /2r2nkh
>
> > > > Man Is A Herbivore! * tinyurl . com /a3cc3
>
> > > > DEAD PEOPLE WALKING * tinyurl . com /zk9fk-Hidequoted text -
>
> > > - Show quoted text -- Hide quoted text -
>
> > - Show quoted text -- Hide quoted text -
>
> - Show quoted text -
On Apr 26, 9:28 pm, ironjustice <teamtan...@hotmail . com > wrote: to
line their pockets. <<
HAS there EVER been a study of blood donation in lupus .. ?
Anemia never killed anyone ..
You get a bit tired but it don't kill ya ..
They have noted one should not be transfused until ones hemoglobin
gets below .. 6 .. so logically one can BE "around 6" .. according to
the .. experts.
So WHAT .. would it BE to .. 'them' .. IF .. say a bunch of people got
together .. say .. and said .. "hey" .. WE .. are the study group.
Saves alot of time and money ..
I don't really know how bad lupus gets .. personally .. but I hear it
gets .. pretty .. bad ..
Sickle patients seem to be cured by keeping their hemoglobin down
around .. there .. coincidentally ..
Some people don't like to use the word .. cure .. but what really
IS .. "long term event free remission" .. ?
Who loves ya.
Tom
Jesus Was A Vegetarian!
* tinyurl . com /2r2nkh
Man Is A Herbivore!
* tinyurl . com /a3cc3
DEAD PEOPLE WALKING
* tinyurl . com /zk9fk
> On Apr 26, 9:17 am, ironjustice <teamtan...@hotmail . com >
> wrote:Aplastic
> anemia <<
>
> Hip surgery .. ?
>
> "These observations are an encouragement to attempt treatment by
> repeated phlebotomies"
>
> Joint Bone Spine 2000;67(3):171-7
>
> Phlebotomy: a treatment of ischaemic necrosis of the femoral head?
> Analysis of a hypothesis.
>
> Bouteiller G
> Service de rhumatologie, center hosptialier, Auch, France.
>
> The treatment of non-traumatic ischaemic osteonecrosis of the femoral
> head (ONFH) remains problematical and there is evidently scope to seek
> for a medical treatment of this disease which often leads to a
> surgical procedure for hip prosthesis.
> If we exclude the context of hemoglobin disorders, necrosis appears
> mainly in adults, when their limb bones contain a fatty marrow.
> Investigations such as intramedullary pressure measurement and
> transosseous phlebography suggest a disorder of the intraosseous blood
> circulation.
> Various studies in animals and man have provided arguments indicating
> that a kind of intraosseous 'obesity' due to hyperplasia and/or
> hypertrophy of the fatty tissue of the femoral marrow play a role in
> the development of necrosis.
> In this respect, the blood flow of the yellow marrow is close to
> ischemia, whereas red marrow flow can be very high.
> In various conditions, mainly hemolytic anemias, the
> femoral yellow marrow can convert to red marrow, which has also been
> described in anemias induced by blood loss. If it is not thought
> unreasonable to consider
> ONFH an 'ischemic' disease, these observations are an encouragement to
> attempt treatment by repeated phlebotomies. This procedure may locally
> restore red marrow, and then an adequate blood flow which could
> stabilize or even reverse
> the lesions if they are diagnosed early.
>
> Publication Types:
>
> Review
> Review, tutorial
> PMID: 10875313, UI: 20331568
>
> ----------------------
>
> Orban H, Cîrstoiu C, Adam R
> Total hip arthroplasty in secondary systemic lupus erythematosus
> femoral head avascular necrosis. [Journal Article]
> Rom J Intern Med 2007; 45(1):123-9.
>
> Systemic lupus erythematosus is a multisystem disease with a large
> spectrum of clinical manifestations and a variable course.
> Lupus is marked by both humoral and cellular immunologic
> abnormalities, including multiple auto-antibodies especially anti DNA
> antibodies.
> Epidemiology - female predominance, occurring usually between second
> and fourth decade of life, more frequently in hispanic and black
> patients.
> Family predominance has been noticed.
> Provocative agents - ultraviolet light, viral infections, drugs and
> situational stresses.
> Pathogenesis - pathological features can affect a large spectrum of
> internal organs and systems - osteoarticulary injuries, skin rash,
> lymphadenopathy, glomerulonephritis, myocarditis, digestive system
> lesions.
> Musculo skeletal abnormalities include migratory arthritis, effusion
> and stiffness in small and large joints.
> Articular erosions are uncommon.
> Skeletal abnormalities include osteopenia and osteonecrosis, due to
> two pathological mechanisms: vasculitis and long term corticotherapy.
> Fifteen to twenty percent of SLE patients are affected by femoral head
> avascular necrosis (FHAN).
> Diagnosis rests on clinical signs - hip pain, limited range of motion,
> walking with a limp.; radiological findings - best grouped in Arlet-
> Ficat standing system; MRI - high sensitivity, especially in
> infraradiological stages.
> Treatment - in incipient stages core decompression represents the best
> therapeutical option.
> In advanced, arthritis stages, total hip arthroplasty (THA) is the
> standart treatment.
> Three implant types are available: bipolar, uncemented and cemented.
> An increased number of cotyloidites occurred after bipolar implants.
> Emphasised osteopenia and excessive bleeding represent
> contraindications for uncemented implants.
> Considering all of this, cemented implants are considered, the right
> choice, methacrylate cement providing strong and durable fixation of
> THA implants to bone.
> No meaningful differences were observed in postoperative functional
> recovery between LSE patients and other etiology FHAN patients.
> --------------------------------------------------------------------------=
------
> Romanian journal of internal medicine = Revue roumaine de médecine
> interne [Rom J Intern Med]
>
> Who loves ya.
> Tom
>
> Jesus Was A Vegetarian! * tinyurl . com /2r2nkh
>
> Man Is A Herbivore! * tinyurl . com /a3cc3
>
> DEAD PEOPLE WALKING * tinyurl . com /zk9fk
>
>
>
> > On Apr 26, 8:31 am, ironjustice <teamtan...@hotmail . com > wrote:
> > Aplastic
> > anemia <<
>
> > * en.wikipedia.org/wiki/Aplastic anemia
>
> > Treating aplastic anemia involves suppression of the immune system, an
> > effect achieved by daily medicine intake, or, in more severe cases, a
> > bone marrow transplant, a potential cure but a risky procedure.[1] The
> > transplanted bone marrow replaces the failing bone marrow cells with
> > new ones from a matching donor. The pluripotent stem cells in the bone
> > marrow reconstitute all three blood cell lines, giving the patient a
> > new immune system, red blood cells, and platelets. However, besides
> > the risk of graft failure, there is also a risk that the newly created
> > white blood cells may attack the rest of the body ("graft-versus-host
> > disease").
>
> > Medical therapy of aplastic anemia often includes a short course of
> > anti-thymocyte globulin (ATG) or anti-lymphocyte globulin (ALG) and
> > several months of treatment with cyclosporin to modulate the immune
> > system. Mild chemotherapy with agents such as cyclophosphamide and
> > vincristine may also be effective. Antibodies therapy, such as ATG,
> > targets T-cells, which are believed to attack the bone marrow.
> > Steroids are generally ineffective.
>
> > In the past, before the above treatments became available, patients
> > with low leukocyte counts were often confined to a sterile room or
> > bubble (to reduce risk of infections), as in the famed case of Ted
> > DeVita.[2]
>
> > Who loves ya.
> > Tom
>
> > Jesus Was A Vegetarian! * tinyurl . com /2r2nkh
>
> > Man Is A Herbivore! * tinyurl . com /a3cc3
>
> > DEAD PEOPLE WALKING * tinyurl . com /zk9fk
>
> > > On Apr 26, 7:25 am, "ironjust...@aol . com " <ironjust...@aol . com >
> > > wrote:continuous, approximately 5-yr transfusion <<
>
> > > One could calculate how much donated blood these .. people .. are
> > > throwing to the wind .. to line their pockets.
> > > They get paid for every transfusion of **donated** blood.
>
> > > Cured the patient by targeting the .. iron.
>
> > > Who loves ya.
> > > Tom
>
> > > Jesus Was A Vegetarian! * tinyurl . com /2r2nkh
>
> > > Man Is A Herbivore! * tinyurl . com /a3cc3
>
> > > DEAD PEOPLE WALKING * tinyurl . com /zk9fk
>
> > > > "Complete recovery after iron chelation in aplastic anemia"
>
> > > > Park SJ, Han CW
> > > > Complete hematopoietic recovery after continuous iron chelation
> > > > therapy in a patient with severe aplastic anemia with secondary
> > > > hemochromatosis. [Journal Article]
> > > > J Korean Med Sci 2008 Apr; 23(2):320-3.
>
> > > > A 16-yr-old male patient with hemochromatosis due to multiple packed=
> > > > red blood cell transfusions was referred to our emergency center for=
> > > > the treatment of severe aplastic anemia and dyspnea. He was diagnose=
d
> > > > with aplastic anemia at 11-yr of age. He had received continuous
> > > > transfusions because an HLA-matched marrow donor was unavailable.
> > > > Following a continuous, approximately 5-yr transfusion, he was noted=
> > > > to develop hemochromatosis. He had a dilated cardiomyopathy and
> > > > required diuretics and digitalis, multiple endocrine and liver
> > > > dysfunction, generalized bleeding, and skin pigmentation. A total
> > > > volume of red blood cell transfusion before deferoxamine therapy was=
> > > > about 96,000 mL. He received a regular iron chelation therapy
> > > > (continuous intravenous infusion of deferoxamine, 50 mg/kg/day for 5=
> > > > days q 3-4 weeks) for approximately seven years after the onset of
> > > > multiple organ failures. His cytopenia and organ dysfunctions began =
to
> > > > be gradually recovered since about 2002, following a 4-yr deferoxami=
ne
> > > > treatment. He showed completely normal ranges of peripheral blood ce=
ll
> > > > counts, heart size, and liver function two years ago. He has not
> > > > received any transfusions for the last four years. This finding
> > > > suggests that a continuous deferoxamine infusion may play a role in
> > > > the immune regulation in addition to iron chelation effect.
> > > > Journal of Korean medical science [J Korean Med Sci]
> > > > --------------------------------------------------------------------=
------------
> > > > More from this journal
>
> > > > Who loves ya.
> > > > Tom
>
> > > > Jesus Was A Vegetarian! * tinyurl . com /2r2nkh
>
> > > > Man Is A Herbivore! * tinyurl . com /a3cc3
>
> > > > DEAD PEOPLE WALKING * tinyurl . com /zk9fk-Hidequoted text -
>
> > > - Show quoted text -- Hide quoted text -
>
> > - Show quoted text -- Hide quoted text -
>
> - Show quoted text -
Re: Whoopsies Cured Another One
On Apr 26, 8:31 am, ironjustice <teamtan...@hotmail . com > wrote: line
their pockets. <<
Sorta like this .. big .. seller ..
"Metformin recorded sales of $2.2 billion and 30.5 million
prescriptions"
"Reduction in body iron stores with metformin"
* care.diabetesjournals.org/cgi/content/full/30/9/2309
Increased ferritin levels and body iron stores found in overweight
and
obese women with PCOS.
The reduction in body iron stores with metformin, as reflected by the
decrease in serum ferritin levels, may be especially favorable in
overweight and obese women with PCOS, considering that increased iron
stores contribute to insulin resistance and hyperinsulinemia by
reducing hepatic insulin extraction and metabolism (29) and by
decreasing glucose uptake in muscle.
Who loves ya.
Tom
Jesus Was A Vegetarian!
* jesuswasavegetarian.7h . com
Man Is A Herbivore!
* tinyurl . com /a3cc3
DEAD PEOPLE WALKING
* tinyurl . com /zk9fk
> On Apr 26, 7:25 am, "ironjust...@aol . com " <ironjust...@aol . com >
> wrote:continuous, approximately 5-yr transfusion <<
>
> One could calculate how much donated blood these .. people .. are
> throwing to the wind .. to line their pockets.
> They get paid for every transfusion of **donated** blood.
>
> Cured the patient by targeting the .. iron.
>
> Who loves ya.
> Tom
>
> Jesus Was A Vegetarian! * tinyurl . com /2r2nkh
>
> Man Is A Herbivore! * tinyurl . com /a3cc3
>
> DEAD PEOPLE WALKING * tinyurl . com /zk9fk
>
>
>
> > "Complete recovery after iron chelation in aplastic anemia"
>
> > Park SJ, Han CW
> > Complete hematopoietic recovery after continuous iron chelation
> > therapy in a patient with severe aplastic anemia with secondary
> > hemochromatosis. [Journal Article]
> > J Korean Med Sci 2008 Apr; 23(2):320-3.
>
> > A 16-yr-old male patient with hemochromatosis due to multiple packed
> > red blood cell transfusions was referred to our emergency center for
> > the treatment of severe aplastic anemia and dyspnea. He was diagnosed
> > with aplastic anemia at 11-yr of age. He had received continuous
> > transfusions because an HLA-matched marrow donor was unavailable.
> > Following a continuous, approximately 5-yr transfusion, he was noted
> > to develop hemochromatosis. He had a dilated cardiomyopathy and
> > required diuretics and digitalis, multiple endocrine and liver
> > dysfunction, generalized bleeding, and skin pigmentation. A total
> > volume of red blood cell transfusion before deferoxamine therapy was
> > about 96,000 mL. He received a regular iron chelation therapy
> > (continuous intravenous infusion of deferoxamine, 50 mg/kg/day for 5
> > days q 3-4 weeks) for approximately seven years after the onset of
> > multiple organ failures. His cytopenia and organ dysfunctions began to
> > be gradually recovered since about 2002, following a 4-yr deferoxamine
> > treatment. He showed completely normal ranges of peripheral blood cell
> > counts, heart size, and liver function two years ago. He has not
> > received any transfusions for the last four years. This finding
> > suggests that a continuous deferoxamine infusion may play a role in
> > the immune regulation in addition to iron chelation effect.
> > Journal of Korean medical science [J Korean Med Sci]
> > ------------------------------------------------------------------------=
--------
> > More from this journal
>
> > Who loves ya.
> > Tom
>
> > Jesus Was A Vegetarian! * tinyurl . com /2r2nkh
>
> > Man Is A Herbivore! * tinyurl . com /a3cc3
>
> > DEAD PEOPLE WALKING * tinyurl . com /zk9fk- Hide quoted text -
>
> - Show quoted text -
On Apr 26, 8:31 am, ironjustice <teamtan...@hotmail . com > wrote: line
their pockets. <<
Sorta like this .. big .. seller ..
"Metformin recorded sales of $2.2 billion and 30.5 million
prescriptions"
"Reduction in body iron stores with metformin"
* care.diabetesjournals.org/cgi/content/full/30/9/2309
Increased ferritin levels and body iron stores found in overweight
and
obese women with PCOS.
The reduction in body iron stores with metformin, as reflected by the
decrease in serum ferritin levels, may be especially favorable in
overweight and obese women with PCOS, considering that increased iron
stores contribute to insulin resistance and hyperinsulinemia by
reducing hepatic insulin extraction and metabolism (29) and by
decreasing glucose uptake in muscle.
Who loves ya.
Tom
Jesus Was A Vegetarian!
* jesuswasavegetarian.7h . com
Man Is A Herbivore!
* tinyurl . com /a3cc3
DEAD PEOPLE WALKING
* tinyurl . com /zk9fk
> On Apr 26, 7:25 am, "ironjust...@aol . com " <ironjust...@aol . com >
> wrote:continuous, approximately 5-yr transfusion <<
>
> One could calculate how much donated blood these .. people .. are
> throwing to the wind .. to line their pockets.
> They get paid for every transfusion of **donated** blood.
>
> Cured the patient by targeting the .. iron.
>
> Who loves ya.
> Tom
>
> Jesus Was A Vegetarian! * tinyurl . com /2r2nkh
>
> Man Is A Herbivore! * tinyurl . com /a3cc3
>
> DEAD PEOPLE WALKING * tinyurl . com /zk9fk
>
>
>
> > "Complete recovery after iron chelation in aplastic anemia"
>
> > Park SJ, Han CW
> > Complete hematopoietic recovery after continuous iron chelation
> > therapy in a patient with severe aplastic anemia with secondary
> > hemochromatosis. [Journal Article]
> > J Korean Med Sci 2008 Apr; 23(2):320-3.
>
> > A 16-yr-old male patient with hemochromatosis due to multiple packed
> > red blood cell transfusions was referred to our emergency center for
> > the treatment of severe aplastic anemia and dyspnea. He was diagnosed
> > with aplastic anemia at 11-yr of age. He had received continuous
> > transfusions because an HLA-matched marrow donor was unavailable.
> > Following a continuous, approximately 5-yr transfusion, he was noted
> > to develop hemochromatosis. He had a dilated cardiomyopathy and
> > required diuretics and digitalis, multiple endocrine and liver
> > dysfunction, generalized bleeding, and skin pigmentation. A total
> > volume of red blood cell transfusion before deferoxamine therapy was
> > about 96,000 mL. He received a regular iron chelation therapy
> > (continuous intravenous infusion of deferoxamine, 50 mg/kg/day for 5
> > days q 3-4 weeks) for approximately seven years after the onset of
> > multiple organ failures. His cytopenia and organ dysfunctions began to
> > be gradually recovered since about 2002, following a 4-yr deferoxamine
> > treatment. He showed completely normal ranges of peripheral blood cell
> > counts, heart size, and liver function two years ago. He has not
> > received any transfusions for the last four years. This finding
> > suggests that a continuous deferoxamine infusion may play a role in
> > the immune regulation in addition to iron chelation effect.
> > Journal of Korean medical science [J Korean Med Sci]
> > ------------------------------------------------------------------------=
--------
> > More from this journal
>
> > Who loves ya.
> > Tom
>
> > Jesus Was A Vegetarian! * tinyurl . com /2r2nkh
>
> > Man Is A Herbivore! * tinyurl . com /a3cc3
>
> > DEAD PEOPLE WALKING * tinyurl . com /zk9fk- Hide quoted text -
>
> - Show quoted text -
