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Headaches and Erythrocytosis
"Oh God I think I'm going to die!"
And then you do.
Eur Neurol. 1994;34(6):316-9.Links
Migrainous stroke and the antiphospholipid antibodies.
Silvestrini M, Matteis M, Troisi E, Cupini LM, Zaccari G, Bernardi G.
Clinic of Neurology, Tor Vergata, University of Rome, Italy.
The pathogenesis of migrainous stroke is controversial. The
possibility that a number of migraine-related strokes is associated
with the presence of antiphospholipid antibodies, a condition
predisposing to coagulopathy, has been suggested. We investigated the
prevalence of lupus anticoagulant and anticardiolipin antibodies in
patients with migrainous stroke. In 6 out of 16 patients with
migrainous cerebral infarction, the presence of antiphospholipids
antibodies was detected. In such patients, the presence of other risk
factors for stroke was significantly lower (chi 2 = 5.6; p = 0.01)
with respect to patients with negative results for antiphospholipid
antibodies. These results suggest that antiphospholipid antibodies
associated with migraine may be an important marker for ischemic
stroke.
PMID: 7851451 [PubMed - indexed for MEDLINE]
Who loves ya.
Tom
Jesus Was A Vegetarian!
http://tinyurl.com/2r2nkh
Man Is A Herbivore!
http://tinyurl.com/a3cc3
DEAD PEOPLE WALKING
http://tinyurl.com/zk9fk
And then you do.
Eur Neurol. 1994;34(6):316-9.Links
Migrainous stroke and the antiphospholipid antibodies.
Silvestrini M, Matteis M, Troisi E, Cupini LM, Zaccari G, Bernardi G.
Clinic of Neurology, Tor Vergata, University of Rome, Italy.
The pathogenesis of migrainous stroke is controversial. The
possibility that a number of migraine-related strokes is associated
with the presence of antiphospholipid antibodies, a condition
predisposing to coagulopathy, has been suggested. We investigated the
prevalence of lupus anticoagulant and anticardiolipin antibodies in
patients with migrainous stroke. In 6 out of 16 patients with
migrainous cerebral infarction, the presence of antiphospholipids
antibodies was detected. In such patients, the presence of other risk
factors for stroke was significantly lower (chi 2 = 5.6; p = 0.01)
with respect to patients with negative results for antiphospholipid
antibodies. These results suggest that antiphospholipid antibodies
associated with migraine may be an important marker for ischemic
stroke.
PMID: 7851451 [PubMed - indexed for MEDLINE]
Who loves ya.
Tom
Jesus Was A Vegetarian!
http://tinyurl.com/2r2nkh
Man Is A Herbivore!
http://tinyurl.com/a3cc3
DEAD PEOPLE WALKING
http://tinyurl.com/zk9fk
On May 9, 9:42=A0am, ironjustice <ironjust...@cashette.com> wrote:
Migrainous stroke <<
NAFLD / nonalcoholic fatty liver disease has been shown to be
effectively treated with phlebotomy / venesection / bloodletting.
Medical people seem to agree everyone has a degree of NAFLD.
Seeing that everyone HAS it / NAFLD then it wouldn't be hard to talk
ones' doctor into a trial of iron reduction / phlebotomy for 'general
purposes'.
This in turn may then cure one of headaches and / or migraines and or
it seems a myriad of different diseases.
With a little convincing and / or .. whining.
=93Whenever someone would complain of a headache he would advise them to
perform cupping.=94
http://tinyurl.com/3mpvbc
--------------------------------
" Three treatments by venesection improved the headache substantially
in frequency, intensity, and duration of attacks "
Iron overload is also called .. erythrocytosis / polycythemia.
Polycythemia / increased red blood cell production has a symptom of
headaches.
Seems iron reduction for headaches .. works.
http://tinyurl.com/3apkvh
---------------------------------------------------------------------------=
=AD---------
This study shows the extent of the .. erythrocytosis / increased
blood cell count / mass / polycythemia .. the LOWER the
hemoglobin / LESS blood cell mass .. the FEWER .. headaches ..
This erythrocytosis / too many red blood cells .. can be caused by
increased highly absorbable .. iron .
Cephalalgia. 2004 Sep;24(9):758-62. Related Articles, Links
Erratum in:
Cephalalgia. 2004 Oct;24(10):913.
Headache prevalence related to haemoglobin and ferritin. The HUNT
Study.
Aamodt AH, Borch-Iohnsen B, Hagen K, Stovner LJ, Asberg A, Zwart JA.
Norwegian National Headache Centre, Trondheim University Hospital,
Trondheim, Norway. anne.hege.aam...@medisin.ntnu.no
As clinic-based studies show an association between headache and both
high and low levels of haemoglobin, we analysed this relationship in
a
population-based cross-sectional study (the HUNT Study). A total of
2385 women aged 20-55 years responded to a headache questionnaire and
gave blood samples for measuring haemoglobin and ferritin. In the
multivariate analyses, adjusting for age and education, there was a
linear trend of decreasing prevalence of headache (P =3D 0.02) and
migraine (P =3D 0.01) with decreasing haemoglobin. In particular,
migraine was less likely among women with low haemoglobin (values <
11.5 g/dl) (odds ratio 0.4, confidence interval 0.2, 0.9). There was
no
correlation between headache prevalence and ferritin. The present
findings may be relevant for the headache reported in polycythaemia
and
chronic altitude sickness. Copyright 2004 Blackwell Publishing Ltd
PMID: 15315532 [PubMed - indexed for MEDLINE]
---------------------------------------------------------------------------=
=AD=AD-----
"Phlebotomy offers a safe and efficient therapy"
American Journal of Clinical Nutrition, Vol. 87, No. 5, 1374-1383,
May
2008
=A9 2008 American Society for Nutrition
---------------------------------------------------------------------------=
=AD-----
ORIGINAL RESEARCH COMMUNICATION
Pathways underlying iron accumulation in human nonalcoholic fatty
liver disease1,2,3
Elmar Aigner, Igor Theurl, Milan Theurl, Dieter Lederer, Heike Haufe,
Otto Dietze, Michael Strasser, Christian Datz and Guenter Weiss
1 From the Department of Internal Medicine, General Hospital
Oberndorf, Oberndorf, Austria (EA, DL, and CD); the Department of
General Internal Medicine, Department of Immunology and Infectious
Diseases, Medical University of Innsbruck, Austria (IT, MT, and GW);
the Department of Pathology (HH and OD) and the First Department of
Medicine (MS), Paracelsus Private Medical University Salzburg,
Austria
Background: Mild iron overload is frequently observed in nonalcoholic
fatty liver disease (NAFLD).
Objective: We aimed to study putative pathways underlying iron
accumulation in NAFLD.
Design: Hepatic and duodenal expression of critical iron molecules in
NAFLD patients with (n =3D 32) and without (n =3D 29) iron overload,
hereditary hemochromatosis (n =3D 10), and controls (n =3D 20) were
investigated. Phlebotomy treatment was performed in 14 NAFLD
patients.
Results: The hepatic expressions of the iron-export protein
ferroportin-1 (FP-1) and of the iron-sensing molecule hemojuvelin
(HJV) were significantly lower in NAFLD patients. The mRNA expression
of the iron-regulatory peptide hepcidin was increased in NAFLD
patients with iron overload, which was paralleled by low duodenal
FP-1
expression. Hepatic mRNA and serum protein concentrations of tumor
necrosis factor- (TNF-) were increased in NAFLD patients and were
inversely correlated with both liver FP-1 and HJV mRNA and positively
associated with body mass index and hepatic hepcidin mRNA.
Accordingly, TNF- inhibited the FP-1 and HJV mRNA formation in HepG2
cells. Phlebotomy treatment of NALFD patients reduced serum ferritin,
transferrin saturation, and TNF- concentrations and improved liver
function tests.
Conclusions: Iron accumulation in NAFLD may result from an impaired
iron export due to down-regulation of FP1 and ineffective hepatic
iron
sensing, as indicated by low HJV expression. TNF- appears to play a
role in exerting these regulatory changes. Increased hepcidin
formation in iron-overloaded NAFLD patients, however, results in
decreased duodenal FP-1 expression, whereas a reduction in liver FP-1
may perpetuate hepatic iron retention. Phlebotomy offers a safe and
efficient therapy for these metabolic disturbances.
-----------------------------
NAFLD may be present to some extent in "just about everybody."
http://care.diabetesjournals.org/cgi/content/full/26/4/1297
Who loves ya.
Tom
Jesus Was A Vegetarian!
http://tinyurl.com/2r2nkh
Man Is A Herbivore!
http://tinyurl.com/a3cc3
DEAD PEOPLE WALKING
http://tinyurl.com/zk9fk
> "OhGodIthinkI'mgoingtodie!"
>
> And then you do.
>
> Eur Neurol. 1994;34(6):316-9.Links
> Migrainous stroke and the antiphospholipid antibodies.
> Silvestrini M, Matteis M, Troisi E, Cupini LM, Zaccari G, Bernardi G.
> Clinic of Neurology, Tor Vergata, University of Rome, Italy.
>
> The pathogenesis of migrainous stroke is controversial. The
> possibility that a number of migraine-related strokes is associated
> with the presence of antiphospholipid antibodies, a condition
> predisposing to coagulopathy, has been suggested. We investigated the
> prevalence of lupus anticoagulant and anticardiolipin antibodies in
> patients with migrainous stroke. In 6 out of 16 patients with
> migrainous cerebral infarction, the presence of antiphospholipids
> antibodies was detected. In such patients, the presence of other risk
> factors for stroke was significantly lower (chi 2 =3D 5.6; p =3D 0.01)
> with respect to patients with negative results for antiphospholipid
> antibodies. These results suggest that antiphospholipid antibodies
> associated with migraine may be an important marker for ischemic
> stroke.
>
> PMID: 7851451 [PubMed - indexed for MEDLINE]
>
> Who loves ya.
> Tom
>
> Jesus Was A Vegetarian!http://tinyurl.com/2r2nkh
>
> Man Is A Herbivore!http://tinyurl.com/a3cc3
>
> DEAD PEOPLE WALKINGhttp://tinyurl.com/zk9fk
Migrainous stroke <<
NAFLD / nonalcoholic fatty liver disease has been shown to be
effectively treated with phlebotomy / venesection / bloodletting.
Medical people seem to agree everyone has a degree of NAFLD.
Seeing that everyone HAS it / NAFLD then it wouldn't be hard to talk
ones' doctor into a trial of iron reduction / phlebotomy for 'general
purposes'.
This in turn may then cure one of headaches and / or migraines and or
it seems a myriad of different diseases.
With a little convincing and / or .. whining.
=93Whenever someone would complain of a headache he would advise them to
perform cupping.=94
http://tinyurl.com/3mpvbc
--------------------------------
" Three treatments by venesection improved the headache substantially
in frequency, intensity, and duration of attacks "
Iron overload is also called .. erythrocytosis / polycythemia.
Polycythemia / increased red blood cell production has a symptom of
headaches.
Seems iron reduction for headaches .. works.
http://tinyurl.com/3apkvh
---------------------------------------------------------------------------=
=AD---------
This study shows the extent of the .. erythrocytosis / increased
blood cell count / mass / polycythemia .. the LOWER the
hemoglobin / LESS blood cell mass .. the FEWER .. headaches ..
This erythrocytosis / too many red blood cells .. can be caused by
increased highly absorbable .. iron .
Cephalalgia. 2004 Sep;24(9):758-62. Related Articles, Links
Erratum in:
Cephalalgia. 2004 Oct;24(10):913.
Headache prevalence related to haemoglobin and ferritin. The HUNT
Study.
Aamodt AH, Borch-Iohnsen B, Hagen K, Stovner LJ, Asberg A, Zwart JA.
Norwegian National Headache Centre, Trondheim University Hospital,
Trondheim, Norway. anne.hege.aam...@medisin.ntnu.no
As clinic-based studies show an association between headache and both
high and low levels of haemoglobin, we analysed this relationship in
a
population-based cross-sectional study (the HUNT Study). A total of
2385 women aged 20-55 years responded to a headache questionnaire and
gave blood samples for measuring haemoglobin and ferritin. In the
multivariate analyses, adjusting for age and education, there was a
linear trend of decreasing prevalence of headache (P =3D 0.02) and
migraine (P =3D 0.01) with decreasing haemoglobin. In particular,
migraine was less likely among women with low haemoglobin (values <
11.5 g/dl) (odds ratio 0.4, confidence interval 0.2, 0.9). There was
no
correlation between headache prevalence and ferritin. The present
findings may be relevant for the headache reported in polycythaemia
and
chronic altitude sickness. Copyright 2004 Blackwell Publishing Ltd
PMID: 15315532 [PubMed - indexed for MEDLINE]
---------------------------------------------------------------------------=
=AD=AD-----
"Phlebotomy offers a safe and efficient therapy"
American Journal of Clinical Nutrition, Vol. 87, No. 5, 1374-1383,
May
2008
=A9 2008 American Society for Nutrition
---------------------------------------------------------------------------=
=AD-----
ORIGINAL RESEARCH COMMUNICATION
Pathways underlying iron accumulation in human nonalcoholic fatty
liver disease1,2,3
Elmar Aigner, Igor Theurl, Milan Theurl, Dieter Lederer, Heike Haufe,
Otto Dietze, Michael Strasser, Christian Datz and Guenter Weiss
1 From the Department of Internal Medicine, General Hospital
Oberndorf, Oberndorf, Austria (EA, DL, and CD); the Department of
General Internal Medicine, Department of Immunology and Infectious
Diseases, Medical University of Innsbruck, Austria (IT, MT, and GW);
the Department of Pathology (HH and OD) and the First Department of
Medicine (MS), Paracelsus Private Medical University Salzburg,
Austria
Background: Mild iron overload is frequently observed in nonalcoholic
fatty liver disease (NAFLD).
Objective: We aimed to study putative pathways underlying iron
accumulation in NAFLD.
Design: Hepatic and duodenal expression of critical iron molecules in
NAFLD patients with (n =3D 32) and without (n =3D 29) iron overload,
hereditary hemochromatosis (n =3D 10), and controls (n =3D 20) were
investigated. Phlebotomy treatment was performed in 14 NAFLD
patients.
Results: The hepatic expressions of the iron-export protein
ferroportin-1 (FP-1) and of the iron-sensing molecule hemojuvelin
(HJV) were significantly lower in NAFLD patients. The mRNA expression
of the iron-regulatory peptide hepcidin was increased in NAFLD
patients with iron overload, which was paralleled by low duodenal
FP-1
expression. Hepatic mRNA and serum protein concentrations of tumor
necrosis factor- (TNF-) were increased in NAFLD patients and were
inversely correlated with both liver FP-1 and HJV mRNA and positively
associated with body mass index and hepatic hepcidin mRNA.
Accordingly, TNF- inhibited the FP-1 and HJV mRNA formation in HepG2
cells. Phlebotomy treatment of NALFD patients reduced serum ferritin,
transferrin saturation, and TNF- concentrations and improved liver
function tests.
Conclusions: Iron accumulation in NAFLD may result from an impaired
iron export due to down-regulation of FP1 and ineffective hepatic
iron
sensing, as indicated by low HJV expression. TNF- appears to play a
role in exerting these regulatory changes. Increased hepcidin
formation in iron-overloaded NAFLD patients, however, results in
decreased duodenal FP-1 expression, whereas a reduction in liver FP-1
may perpetuate hepatic iron retention. Phlebotomy offers a safe and
efficient therapy for these metabolic disturbances.
-----------------------------
NAFLD may be present to some extent in "just about everybody."
http://care.diabetesjournals.org/cgi/content/full/26/4/1297
Who loves ya.
Tom
Jesus Was A Vegetarian!
http://tinyurl.com/2r2nkh
Man Is A Herbivore!
http://tinyurl.com/a3cc3
DEAD PEOPLE WALKING
http://tinyurl.com/zk9fk
> "OhGodIthinkI'mgoingtodie!"
>
> And then you do.
>
> Eur Neurol. 1994;34(6):316-9.Links
> Migrainous stroke and the antiphospholipid antibodies.
> Silvestrini M, Matteis M, Troisi E, Cupini LM, Zaccari G, Bernardi G.
> Clinic of Neurology, Tor Vergata, University of Rome, Italy.
>
> The pathogenesis of migrainous stroke is controversial. The
> possibility that a number of migraine-related strokes is associated
> with the presence of antiphospholipid antibodies, a condition
> predisposing to coagulopathy, has been suggested. We investigated the
> prevalence of lupus anticoagulant and anticardiolipin antibodies in
> patients with migrainous stroke. In 6 out of 16 patients with
> migrainous cerebral infarction, the presence of antiphospholipids
> antibodies was detected. In such patients, the presence of other risk
> factors for stroke was significantly lower (chi 2 =3D 5.6; p =3D 0.01)
> with respect to patients with negative results for antiphospholipid
> antibodies. These results suggest that antiphospholipid antibodies
> associated with migraine may be an important marker for ischemic
> stroke.
>
> PMID: 7851451 [PubMed - indexed for MEDLINE]
>
> Who loves ya.
> Tom
>
> Jesus Was A Vegetarian!http://tinyurl.com/2r2nkh
>
> Man Is A Herbivore!http://tinyurl.com/a3cc3
>
> DEAD PEOPLE WALKINGhttp://tinyurl.com/zk9fk
