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Immunity and Vitamin E
Gives a bit of credence to the oxidative stress hypothesis of Aids.
Sheridan PA, Beck MA
The Immune Response to Herpes Simplex Virus Encephalitis in Mice Is
Modulated by Dietary Vitamin E. * tinyurl . com /2ylpku
J Nutr 2008 Jan; 138(1):130-137.
Herpes simplex virus encephalitis (HSE) is the most common fatal
sporadic encephalitis in humans. HSE is primarily caused by herpes
simplex virus (HSV)-1 infection of the brain. HSE results in increased
levels of oxidative stress, including the production of reactive
oxygen species, free radicals, and neuroinflammation.
The most biologically active form of vitamin E (VE) is alpha-
tocopherol (alpha-TOC).
In cellular membranes, alpha-TOC prevents lipid peroxidation by
scavenging free radicals and functioning as an antioxidant.
Supplementation with VE has been shown to decrease immunosenescence,
improve immune function, and may be neuroprotective.
To determine how VE deficiency and VE supplementation would alter the
pathogenesis of HSE, we placed weanling male BALB/cByJ mice on VE-
deficient (VE-D), VE-adequate (VE-A), or 10x VE-supplemented diets for
4 wk, and then infected the mice intranasally with HSV-1. VE-D mice
had more severe symptoms of encephalitis than VE-A mice, including
weight loss, keratitis, hunched posture, and morbidity. VE-D mice had
increased cytokine and chemokine expression in the brain and increased
viral titers. In contrast, VE supplementation failed to decrease
cytokine production and had no effect on viral titer. We demonstrated
that adequate levels of VE are important in limiting HSE pathology and
that 10x supplementation does not enhance protection.
J Nutr
--------------------------------------------------------------------------------
* w w w .virusmyth . net /aids/perthgroup/index.html
"That AIDS and all the phenomena inferred as "HIV" are induced by
changes in cellular redox brought about by the oxidative nature of
substances and exposures common to all the AIDS risk groups and to
the
cells used in the "culture" and "isolation" of HIV."
Who loves ya.
Tom
Jesus Was A Vegetarian!
* jesuswasavegetarian.7h . com
Man Is A Herbivore!
* tinyurl . com /a3cc3
DEAD PEOPLE WALKING
* tinyurl . com /zk9fk
Sheridan PA, Beck MA
The Immune Response to Herpes Simplex Virus Encephalitis in Mice Is
Modulated by Dietary Vitamin E. * tinyurl . com /2ylpku
J Nutr 2008 Jan; 138(1):130-137.
Herpes simplex virus encephalitis (HSE) is the most common fatal
sporadic encephalitis in humans. HSE is primarily caused by herpes
simplex virus (HSV)-1 infection of the brain. HSE results in increased
levels of oxidative stress, including the production of reactive
oxygen species, free radicals, and neuroinflammation.
The most biologically active form of vitamin E (VE) is alpha-
tocopherol (alpha-TOC).
In cellular membranes, alpha-TOC prevents lipid peroxidation by
scavenging free radicals and functioning as an antioxidant.
Supplementation with VE has been shown to decrease immunosenescence,
improve immune function, and may be neuroprotective.
To determine how VE deficiency and VE supplementation would alter the
pathogenesis of HSE, we placed weanling male BALB/cByJ mice on VE-
deficient (VE-D), VE-adequate (VE-A), or 10x VE-supplemented diets for
4 wk, and then infected the mice intranasally with HSV-1. VE-D mice
had more severe symptoms of encephalitis than VE-A mice, including
weight loss, keratitis, hunched posture, and morbidity. VE-D mice had
increased cytokine and chemokine expression in the brain and increased
viral titers. In contrast, VE supplementation failed to decrease
cytokine production and had no effect on viral titer. We demonstrated
that adequate levels of VE are important in limiting HSE pathology and
that 10x supplementation does not enhance protection.
J Nutr
--------------------------------------------------------------------------------
* w w w .virusmyth . net /aids/perthgroup/index.html
"That AIDS and all the phenomena inferred as "HIV" are induced by
changes in cellular redox brought about by the oxidative nature of
substances and exposures common to all the AIDS risk groups and to
the
cells used in the "culture" and "isolation" of HIV."
Who loves ya.
Tom
Jesus Was A Vegetarian!
* jesuswasavegetarian.7h . com
Man Is A Herbivore!
* tinyurl . com /a3cc3
DEAD PEOPLE WALKING
* tinyurl . com /zk9fk
ironjustice wrote:
> The most biologically active form of vitamin E (VE) is alpha-
> tocopherol (alpha-TOC).
I doubt that.
--
Juhana
Ravintoblogini:
* ruohikolla.blogspot . com /
> The most biologically active form of vitamin E (VE) is alpha-
> tocopherol (alpha-TOC).
I doubt that.
--
Juhana
Ravintoblogini:
* ruohikolla.blogspot . com /
