Re: Vitamin K2 reduces the risk of prostate cancerOn Apr 9, 8:50 pm, Taka <taka0...@gmail,com > wrote:
> On Apr 10, 1:21 am, "Juhana Harju" <n...@mail.fi> wrote:
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> > Juhana Harju wrote:
> > > Vitamin K2 seems to reduce the risk of prostate cancer according to
> > > this study. In Western diets the best vitamin K2 sources are some
> > > cheeses, yogurt, chicken, and turkey. The Japanese soy food /natto/
> > > is much higher in vitamin K2 but it has different kind of vitamin K2
> > > (menaquinone-7) and it is not clear if it would also have the similar
> > > effect, but I guess it would.
> > > ----------------------------------------------------------------------
>
> > > Nimptsch K, Rohrmann S, Linseisen J.
>
> > > Dietary intake of vitamin K and risk of prostate cancer in the
> > > Heidelberg cohort of the European Prospective Investigation into
> > > Cancer and Nutrition (EPIC-Heidelberg).
>
> > > American Journal of Clinical Nutrition, Vol. 87, No. 4, 985-992,
> > > April 2008.
> > > Background: Anticarcinogenic activities of vitamin K have been
> > > observed in various cancer cell lines, including prostate cancer
> > > cells. Epidemiologic studies linking dietary intake of vitamin K with
> > > the development of prostate cancer have not yet been conducted.
>
> > > Objective: We evaluated the association between dietary intake of
> > > phylloquinone (vitamin K1) and menaquinones (vitamin K2) and total and
> > > advanced prostate cancer in the Heidelberg cohort of the European
> > > Prospective Investigation into Cancer and Nutrition.
>
> > > Design: At baseline, habitual dietary intake was assessed by means of
> > > a food-frequency questionnaire. Dietary intake of phylloquinone and
> > > menaquinones (MK-4-14) was estimated by using previously published
> > > HPLC-based food-content data. Multivariate-adjusted relative risks of
> > > total and advanced prostate cancer in relation to intakes of
> > > phylloquinone and menaquinones were calculated in 11 319 men by means
> > > of Cox proportional hazards regression.
>
> > > Results: During a mean follow-up time of 8.6 y, 268 incident cases of
> > > prostate cancer, including 113 advanced cases, were identified. We
> > > observed a nonsignificant inverse association between total prostate
> > > cancer and total menaquinone intake [multivariate relative risk
> > > (highest compared with lowest quartile): 0.65; 95% CI: 0.39, 1.06].
> > > The association was stronger for advanced prostate cancer (0.37;
> > > 0.16, 0.88; P for trend = 0.03). Menaquinones from dairy products had
> > > a stronger inverse association with advanced prostate cancer than did
> > > menaquinones from meat. Phylloquinone intake was unrelated to
> > > prostate cancer incidence (1.02; 0.70, 1.48).
> > > Conclusions: Our results suggest an inverse association between the
> > > intake of menaquinones, but not that of phylloquinone, and prostate
> > > cancer. Further studies of dietary vitamin K and prostate cancer are
> > > warranted.
> > > http :// www .ajcn.org/cgi/content/abstract/87/4/985
>
> > > [Not in PubMed yet.]
>
> > Vitamin K researcher, Professor Ceer Vermeer states in the news article of
> > NutraIngredients that vitamin K2 has a anti-tumor effect:
>
> > "'The anti-tumor effect of K2 vitamins has been suggested in several other
> > (mainly Japanese) papers; in most cases these papers were based on smaller
> > numbers, however. Also, in Japan it is usual to provide very high doses of
> > the short-chain menaquinone-4 (45 mg/day or higher)', said Dr. Vermeer.
>
> > 'The elegance of the Nimptsch paper is that the effect is found at
> > nutritional doses of vitamin K', he added."
>
> > http :// tinyurl,com /5zk9gs
>
> > Thanks to Matti Narkia's bookmarking I found this abstract which explains
> > that vitamin K2 induces a slow apoptosis (death) of cancer cells. That
> > should be the mechanism by which vitamin K2 is associated with reduced
> > prostate cancer risk.
>
> > http :// tinyurl,com /69oa2d
>
> > --
> > Juhana
>
> > Ravintoblogini: http :// ruohikolla.blogspot,com /
>
> Now tell me what is better for killing cancer cells - VitK2 or
> Omega-3s? Both seem to work via the same mechanism, i.e. oxidative
> stress leading to apoptosis which is preventable by VitE. Japanese
> have higher intakes of both and have therefore lower cancer rates and
> are less obese (more apoptosis going on in their bodies). But the
> world longest living people are not from Japan but from Brazil and
> France ... (the 113 old Japanese just died before reaching 120).
>
> Taka- Hide quoted text -
>
> - Show quoted text -
Taka, I'll tell you the truth, I would prize longevity but unless I
will be able to lob tennis balls over a net and take salsa lessons, I
really do not aim for 120. I do not do these things now, but if you
live that long it would be nice to try something new. I would
consider myself lucky to live to an active independent 110.
Dolores