Women face increased cancer risk
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One in seven women could develop breast cancer if public health
trends do not improve, experts warn.
Researchers found the risk to women carrying a gene which can lead to
the disease has increased dramatically in the last 60 years.
The study, at the Genesis Breast Cancer Prevention Centre in
Manchester, suggests a lifestyle change is key.
Having families earlier and avoiding long term use of female hormones
in HRT and contraceptives were recommended.
Experts also suggested regular exercise and a healthy diet could make
a difference.
One in 10 women in the UK currently develop breast cancer by the age
of 80 but researchers fear this may rise to one in seven by 2024
unless changes are made.
Gene mutations
Around one in 500 people are said to carry the gene mutations which
result in an 85-90% chance of developing breast cancer.
Professor Gareth Evans, who led the study of more than 1,400 women
who carried the high-risk genes, said: "This rise in the incidence of
breast cancer is reflected in the general population.
"In 1984 only one in 13 women were projected to develop breast
cancer.
"In 2004 this reached one in 10 and, if the rates rise as they are
currently doing so, it is predicted that by 2024 one in seven to
eight women will develop breast cancer by 80 years of age.
"That will translate into an extra 4,000 deaths, unless further
improvements in treatments occur."
The report, by the consultant in medical genetics at St Mary's
Hospital and Christie Hospital, both in Manchester, will be published
in the BMC Cancer journal.
It showed that women born before 1920 who carry faults in the
high-risk genes had a 7.5% chance of developing breast cancer by the
age of 40.
However, women born after 1960 had a risk of up to 40%.
The Genesis Appeal, a breast cancer prevention charity, has funded
the purpose-built £14m centre in Wythenshawe which brings together
medical experts to conduct diagnosis, education and research into the
disease.
Story from BBC NEWS:
http :// news.bbc.co.uk/go/pr/fr/-/2/hi/uk_news/england/manchester/74272
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