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Pathology and laboratory medicine.

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Stress and DHEA

Reply from: James Michael Howard
Date: 22 Dec 2006, 17:12
Stress and DHEA

Bull Exp Biol Med. 2006 May;141(5):571-3.Prolonged decrease in stress
reactivity caused by dehydroepiandrosterone sulfate.

Obut TA, Ovsyukova MV, Cherkasova OP.
Institute of Physiology, Siberian Division, Russian Academy of Medical
Sciences, Novosibirsk.

In male rats exposed to repeated stress, the decrease in stress reactivity
produced by subcutaneous injection of dehydroepiandrosterone sulfate
(recorded by the decrease in stress-induced concentrations of
corticosterone and adrenocorticotropic hormone in blood plasma) was
observed 1-6 days postinjection and involved central regulatory mechanisms.





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