Dangerous unnecessary angioplastiesSeem's like Dr. Chung was right IN .. 'the courage of his convictions'
..
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"You lost
your job because you talked yourself out of it."
* groups.google . com /group/sci.med.cardiology/msg/f2d015592dcf777c
"unnecessary angioplasties"
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According to Denise Gellene of The Los Angeles Times angioplasty may
actually increase the chances of someone having another attack:
The study of more than 2,000 patients in 27 countries focused on the
outcomes of angioplasties performed more than 24 hours and up to 28
days after the patients first developed symptoms of a heart attack.
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Study puts a time limit on angioplasties' usefulness
By Denise Gellene, Times Staff Writer
11:44 AM PST, November 14, 2006
Using angioplasty to unclog arteries more than 24 hours after a
patient's heart attack does no good and may increase the chances of
another attack, researchers said today.
The findings contradict a long-held belief that opening vessels to
restore blood flow is always beneficial and could spare thousands of
patients from undergoing the costly and potentially risky procedure.
The report "is a sobering reminder that sometimes our preconceived
notions turn out not to be accurate," said Dr. Prediman K. Shah,
director of cardiology at Cedars-Sinai Medical Center, who was not
involved in the research.
Dr. L. David Hillis of the University of Texas Southwestern said the
study should bring an end to delayed angioplasties in stable heart
attack patients. The surgery typically costs between $10,000 and
$15,000, he said.
"There should be a substantial savings in patient discomfort and also
monetarily," said Hillis, who coauthored an editorial on the study,
both of which were posted on the website of the New England Journal of
Medicine.
The study was presented today at the annual meeting of the American
Heart Assn. in Chicago. The National Heart, Lung and Blood Institute
paid for the study.
The study of more than 2,000 patients in 27 countries focused on the
outcomes of angioplasties performed more than 24 hours and up to 28
days after the patients first developed symptoms of a heart attack.
Angioplasty involves threading a catheter through a blood vessel in the
groin to the site of the blockage, which may be a blood clot or a
buildup of plaque on artery walls. After a ballon is inflated to open
the artery, a wire mesh tube, or stent, is typically positioned inside
the vessel to keep it open.
If performed within 12 hours after a heart attack, the procedure can
preserve heart muscle and reduce deaths, researchers said. That's why
people who may be experiencing a heart attack are urged to get
immediate help.
Previous research on angioplasties performed outside the crucial
12-hour window has produced conflicting results. Some studies found
that the procedure offered little benefit. Others concluded that the
restoration of blood flow improved patients' life expectancy even if
the angioplasty came too late to salvage heart muscle.
About 100,000 people in the U.S. each year seek treatment for mild
heart attacks caused by blockages after more than 12 hours have passed.
Many of these patients delay getting help because they have vague
symptoms and mistake their heart attacks for indigestion or muscle
cramping. Roughly half of them undergo angioplasty.
The latest study divided 2,166 patients into two groups: One received
standard medications to prevent blood clots and maintain heart rhythm;
the second got the same drugs in addition to an angioplasty.
After four years, the groups had comparable incidences of death,
serious heart failure or recurrent heart attacks.
"There was absolutely no benefit," said Dr. Judith Hochman, director of
cardiovascular research at New York University and lead author of the
report.
But there were worrisome indications that risks associated with
angioplasty might increase over time.
At the end of five years, 21.2% of patients receiving angioplasty had
another attack compared to 16.5% of group receiving only heart
medications. Researchers said the difference was not statistically
significant.
Hochman said researchers were very surprised to discover that
angioplasty might leave patients worse off.
She said it was possible that the restoration of blood flow caused the
shutdown of smaller vessels that had sprouted over time to handle some
of the work of the clogged artery. In such a case, the smaller vessels
would not be available to supply the heart if the angioplasty closed
and caused a second heart attack.
Another possibility, she said, was that the benefits of restoring blood
flow were offset by heart muscle damage caused by debris from blockages
dislodged during the angioplasty procedure.
denise.gellene@latimes . com
Who loves ya.
Tom
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