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Medical/scientific aspects of immune illness.

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Would a PhD in immunology be good for a freshly certified rheumatologist persuing a research career?

Reply from: DarkProtoman
Date: 26 Nov 2007, 08:56
Would a PhD in immunology be good for a freshly certified rheumatologist persuing a research career?

Would a PhD in immunology be good for a freshly certified
rheumatologist persuing a research career? Or should I just get a MSc/
MPhil. Or maybe a DM --I studied medicine at Oxford, and they grant a
BMBCh --Bachelor of Medicine and Bachelor of Surgery--; DM --Doctor of
Medicine-- is the higher research doctorate-- --you don't have to do
the research at Oxford--. I currently am an attending at Massachussets
General Hospital. Thank you so much!!!!

Reply from: D P Burns
Date: 27 Nov 2007, 13:16
Re: Would a PhD in immunology be good for a freshly certified rheumatologist persuing a research car


"DarkProtoman" <Protoman2050@gmail . com > wrote in message
news:cb1fe90f-6d5c-452a-b42e-c8fc93be5de7@s12g2000prg.googlegroups . com ...
> Would a PhD in immunology be good for a freshly certified
> rheumatologist persuing a research career? Or should I just get a MSc/
> MPhil. Or maybe a DM --I studied medicine at Oxford, and they grant a
> BMBCh --Bachelor of Medicine and Bachelor of Surgery--; DM --Doctor of
> Medicine-- is the higher research doctorate-- --you don't have to do
> the research at Oxford--. I currently am an attending at Massachussets
> General Hospital. Thank you so much!!!!

Highly unlikely that you will get a rational answer on this NG as most are
'wack jobs'.



Reply from: trigonometry1972@gmail . com
Date: 29 Nov 2007, 05:27
Re: Would a PhD in immunology be good for a freshly certified rheumatologist persuing a research car

On Nov 25, 11:56 pm, DarkProtoman <Protoman2...@gmail . com > wrote:
> Would a PhD in immunology be good for a freshly certified
> rheumatologist persuing a research career? Or should I just get a MSc/
> MPhil. Or maybe a DM --I studied medicine at Oxford, and they grant a
> BMBCh --Bachelor of Medicine and Bachelor of Surgery--; DM --Doctor of
> Medicine-- is the higher research doctorate-- --you don't have to do
> the research at Oxford--. I currently am an attending at Massachussets
> General Hospital. Thank you so much!!!!



I'll suggest that Bryan Heit who has posted here might have
an opinion. You can Google this forum for his name.
He is still working toward his PHD.
Keep asking as there should be someone in your
environs that would have a sense of the optimal choice.
Be careful how you frame your questions and get
multiple opinions.

Reply from: DarkProtoman
Date: 29 Nov 2007, 14:28
Re: Would a PhD in immunology be good for a freshly certified rheumatologist persuing a research car

On Nov 28, 8:27 pm, trigonometry1...@gmail . com wrote:
> On Nov 25, 11:56 pm, DarkProtoman <Protoman2...@gmail . com > wrote:
>
> > Would a PhD in immunology be good for a freshly certified
> > rheumatologist persuing a research career? Or should I just get a MSc/
> > MPhil. Or maybe a DM --I studied medicine at Oxford, and they grant a
> > BMBCh --Bachelor of Medicine and Bachelor of Surgery--; DM --Doctor of
> > Medicine-- is the higher research doctorate-- --you don't have to do
> > the research at Oxford--. I currently am an attending at Massachussets
> > General Hospital. Thank you so much!!!!
>
> I'll suggest that Bryan Heit who has posted here might have
> an opinion. You can Google this forum for his name.
> He is still working toward his PHD.
> Keep asking as there should be someone in your
> environs that would have a sense of the optimal choice.
> Be careful how you frame your questions and get
> multiple opinions.

Sounds like good advice. My research interests are the immunopathology
of Wegener's granulomatosis and Churg-Strauss disease, and the effect
of cytokines.

Reply from: trigonometry1972@gmail . com
Date: 01 Dec 2007, 10:37
Re: Would a PhD in immunology be good for a freshly certified rheumatologist persuing a research car

> My research interests are the immunopathology
> of Wegener's granulomatosis and Churg-Strauss disease,
> and the effect of cytokines.

Both are autoimmune diseases. Among other things, granulomatosis
results in a high level local activation of 25 OH vitamin D into
1,25 (OH)2 vitamin D aka calcitriol (PMID: 8042652 & PMID: 8267026)
which in turn can lead to an excessive the systemic level of
calcitriol.
There is a certain irony in this
as there is reason to believe that that lack of sufficient
vitamin D levels plays a role in the development in at
least some (and perhaps most) autoimmune disorders
such as MS and type 1 DM.
There is said to be an increased of frequency of Wegener's
as one goes north in the northern hemisphere (PMID: 16368729).
This suggestive this vitamin connection may play a role
in this disease as well. Virus infections maybe the
precipitating event and a low vitamin D status maybe a permissive
state? It also would seem that the hormonal changes associated
with aging may also be permissive, in my tenative opinion.
And then there is some work that in some autoimmune
diseases such a systemic lupus erythematosus (SLE) that
there can be antibodies to vitamin D. This assumes
one might dare to generalize about the autoimmune diseases
(PMID: 17785327).

Have Fun.......Trig





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