Low immunity against fungi

Low immunity against fungi

I have low immune strength against fungi.
What can I do?

For the rest the immune system seems normal. Against viruses it is very
strong: vaccinations last for many tens of years instead of just 10y, I
even overreact to vaccinations and usually a lower dose than normal is
enough.

The problem is fungi. I could never in all my life get rid of the fungus
between the fingers in my feet. I have to use antifungals there EVERY
time I have a shower or the fungus will proliferate up to the point
where the fingers of my feet bleed.

And recently I got what seems to be a candida esophagitis, started with
just an occasional esophagitis from FANS! :(( and now I will need
systemic fluconazole.

What is exactly the problem in me and how can I fix it?

Below follows complete blood cell count: (forgive possible misspells, I
am translating...)

---------------
erithrocytes = 5.12 [4.6 - 6.2]
ematocryth = 43.9 [40 - 50]
MCV = 85.7 [83 - 97]
hemoglobin = 15.1 [14 - 18]
MCH = 29.4 [27 - 32]
MCHC = 34.3 [32 - 36]

Leukocytes = 8200 [5000 - 9000]

Leukocytes composition:
Neutrophils = 58 [55 - 70]
Eosinophils = 4 [1 - 4]
Basophils = 0 [0 - 1]
Lymphocytes = 34 [25 - 35]
Monocytes = 4 [3 - 8]

Platelets count = 208,000 [150,000 - 450,000]

Morphologic microscopic examination = normocytes normochromia
---------------

Thank you in advance
1u1x

Re: Low immunity against fungi

On Nov 30, 4:33 pm, 1u1x <1...@1u1x.org> wrote:
> I have low immune strength against fungi.
> What can I do?
>
> For the rest the immune system seems normal. Against viruses it is very
> strong: vaccinations last for many tens of years instead of just 10y, I
> even overreact to vaccinations and usually a lower dose than normal is
> enough.
>
> The problem is fungi. I could never in all my life get rid of the fungus
> between the fingers in my feet. I have to use antifungals there EVERY
> time I have a shower or the fungus will proliferate up to the point
> where the fingers of my feet bleed.
>
> And recently I got what seems to be a candida esophagitis, started with
> just an occasional esophagitis from FANS! :(( and now I will need
> systemic fluconazole.
>
> What is exactly the problem in me and how can I fix it?
>
> Below follows complete blood cell count: (forgive possible misspells, I
> am translating...)
>
> ---------------
> erithrocytes = 5.12 [4.6 - 6.2]
> ematocryth = 43.9 [40 - 50]
> MCV = 85.7 [83 - 97]
> hemoglobin = 15.1 [14 - 18]
> MCH = 29.4 [27 - 32]
> MCHC = 34.3 [32 - 36]
>
> Leukocytes = 8200 [5000 - 9000]
>
> Leukocytes composition:
> Neutrophils = 58 [55 - 70]
> Eosinophils = 4 [1 - 4]
> Basophils = 0 [0 - 1]
> Lymphocytes = 34 [25 - 35]
> Monocytes = 4 [3 - 8]
>
> Platelets count = 208,000 [150,000 - 450,000]
>
> Morphologic microscopic examination = normocytes normochromia
> ---------------
>
> Thank you in advance
> 1u1x

Well, one of the main reasons is that fungi aren't very immunogenic,
due to them lacking antigens, so B cells can't produce antibodies
against them --they can't "see" the fungi--. They also tend to produce
biofilms which protect them from cytokines produced by cytotoxic T
cells. So antifungals are needed to kill them, so the macrophages can
clear your body of them. Are you immunosupressed? This may explain why
you get so many fungal infections. Also, certain people have a genetic
susceptability to fungi; I have severe tinea pedis susceptible to
griseofulvin, however, my pediatrician --I'm 16 and enrolled in
Cerritos College; I want to be a doctor-- didn't give a long enough
course --only 30 days--, so around a week later, it came back. Then he
decided to put me on --$800/course!!!!-- itraconazole, which didn't
work at all, so he put me back on griseofulvin. But my compliance was
horrible, b/c the meds got lost in plain sight.

I suggest that you suggest to your internist that he put you on
ultramicrosize griseofulvin for 30 days. That should cure your fungal
infection.