STUDY: Outbreak of surgical infection caused by non-tuberculous mycobacteria in breast implants in

STUDY: Outbreak of surgical infection caused by non-tuberculous mycobacteria in breast implants in

* breastimplantAwareness.blogspot . com

w w w .BreastImplantAwareness.org/


J Hosp Infect. 2007 Sep 18;

* w w w .ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list uids=17881086&itool=pubmed DocSum
Outbreak of surgical infection caused by non-tuberculous mycobacteria
in breast implants in Brazil.

Padoveze MC, Fortaleza CM, Freire MP, Brandão de Assis D, Madalosso G,
Pellini AC, César ML, Pisani Neto V, Beltramelli MM, Chimara E,
Ferrazoli L, da Silva Telles MA, Sampaio JL, Leão SC.
Centro de Vigilância Epidemiológica ‘Prof. Alexandre Vranjac’, State
Health Department, Hospital Infection Division, São Paulo, Brazil.

SUMMARY: We investigated an outbreak caused by non-tuberculous
mycobacteria (NTM) related to breast implant surgery in the city of
Campinas, Brazil, by means of a retrospective cohort and molecular
epidemiological study. A total of 492 records of individuals having
breast surgery in 12 hospitals were evaluated. Twelve isolates were
analysed using four different molecular typing methods. There were 14
confirmed cases, 14 possible cases and one probable case. One
probable, nine possible and 12 confirmed cases were included in a
cohort study; all occurred in eight of the hospitals and the confirmed
cases in five. Univariate analysis showed that patients who had had
breast reconstruction surgery in hospitals A and B were more likely to
have NTM infections. No risk factor was independently associated with
NTM infection in the multivariate model. The isolates obtained from
patients at each hospital showed different molecular patterns,
excluding isolates from hospital C that repeatedly showed the same
genotype for approximately one year. In conclusion, this outbreak was
caused by polyclonal strains at different institutions, and in one
hospital a unique genotype caused most cases. No specific risk factors
were found.

Re: STUDY: Outbreak of surgical infection caused by non-tuberculous mycobacteria in breast implants

On Sep 21, 11:33 pm, Ilena Rose <B...@mundo . com > wrote:
> * breastimplantAwareness.blogspot . com
>
> w w w .BreastImplantAwareness.org/
>
> J Hosp Infect. 2007 Sep 18;
>
> * w w w .ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Retrieve&dopt=
=...
> Outbreak of surgical infection caused by non-tuberculous mycobacteria
> in breast implants in Brazil.
>
> Padoveze MC, Fortaleza CM, Freire MP, Brandão de Assis D, Madalosso G,
> Pellini AC, César ML, Pisani Neto V, Beltramelli MM, Chimara E,
> Ferrazoli L, da Silva Telles MA, Sampaio JL, Leão SC.
> Centro de Vigilância Epidemiológica 'Prof. Alexandre Vranjac', State
> Health Department, Hospital Infection Division, São Paulo, Brazil.
>
> SUMMARY: We investigated an outbreak caused by non-tuberculous
> mycobacteria (NTM) related to breast implant surgery in the city of
> Campinas, Brazil, by means of a retrospective cohort and molecular
> epidemiological study. A total of 492 records of individuals having
> breast surgery in 12 hospitals were evaluated. Twelve isolates were
> analysed using four different molecular typing methods. There were 14
> confirmed cases, 14 possible cases and one probable case. One
> probable, nine possible and 12 confirmed cases were included in a
> cohort study; all occurred in eight of the hospitals and the confirmed
> cases in five. Univariate analysis showed that patients who had had
> breast reconstruction surgery in hospitals A and B were more likely to
> have NTM infections. No risk factor was independently associated with
> NTM infection in the multivariate model. The isolates obtained from
> patients at each hospital showed different molecular patterns,
> excluding isolates from hospital C that repeatedly showed the same
> genotype for approximately one year. In conclusion, this outbreak was
> caused by polyclonal strains at different institutions, and in one
> hospital a unique genotype caused most cases. No specific risk factors
> were found.


Why would you post this to sci.med.immunology? Totally off-topic.