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co-infection can lead to virus eradiacation?
co-infection can lead to virus eradiacation?
***>
( HBV AND HCV 1-b ) co-infection can lead to virus eradiacation?
I had to read this more than once to believe it. I'm co-infected too.
***>
September 05, 2007
Factors Influencing Self-Recovery from Hepatitis C
As reported in the August 21, 2007 edition of the World Journal of
Gastroenterology, researchers investigated why some people are able to
spontaneously recover from the Hepatitis C virus. This study found the
following factors responsible for a person's ability, or inability, to
self-recover from the virus - quantity of Hepatitis C antibody, co-infection
with Hepatitis B, and the active use of IV drugs.
Source: World Journal of Gastroenterology
Date: August 29, 2007
w w w .sciencedaily . com
Who Will Recover Spontaneously From Hepatitis C Virus Infection?
Science Daily - More than 3% of world population is infected with hepatitis
C virus (HCV). The outcome of HCV infections is either self recovery or
chronic hepatitis, and many of the chronic infections will develop into
liver cirrhosis or liver cancer. Since there is no cure for chronic
hepatitis C, nor is there any approved vaccine for this virus, hepatitis C
is currently a major health problem worldwide.
Twenty to fifty percent of HCV infected patients recovers spontaneously. The
hepatitis C patients and their relatives like to know if his/her infection
would fall into the category for self recovery.
A research article to be published on August 21 in the World Journal of
Gastroenterology addresses this question.
The research team led by Dr. Mihm from Georg-August-Universität spent more
than 8 years working with a cohort of 67 patients who spontaneously
recovered from HCV infection. In addition to these, the researchers included
a similar number of patients with chronic HCV infection. Large sample size
allowed these investigators to obtain results with great statistical
significance, and to draw very reliable conclusions.
One conclusion reported by the investigators is, patients who self recovered
usually have lower levels of HCV antibody. Thus patients with lower HCV
antibody titer may have a brighter clinical outcome. However, for a
practical standard to be established to define a low HCV antibody titer,
more effort is needed by investigators in the future.
***>
Another interesting conclusion reached by these investigators is,
co-infection by hepatitis B virus (HBV) is associated with a higher
possibility of self recovery. The investigators suggested that the infection
of HBV interferes with the HCV replication, which would finally lead to
virus eradiacation.. HCV patients co-infected by hepatitis A virus also have
a better chance of self recovery, possibly by a similar mechanism.
***>
Active iv drug users are less likely to self recover, for a couple of
reasons: 1, they have a higher incidence of re-infection; 2, drugs have been
shown to inhibit the expression of antiviral cytokines such as IFN-a and
IFN-g; 3, HCV replication has been shown to be enhanced both by morphine use
and morphine withdrawal.
Several different genotypes of HCV were discovered. The HCV genotype studied
by Dr. Milm¡¯s group is type 1b, which is the prevalent genotype in Germany,
and in China.
Note: This story has been adapted from a news release issued by World
Journal of Gastroenterology.
***>
( HBV AND HCV 1-b ) co-infection can lead to virus eradiacation?
I had to read this more than once to believe it. I'm co-infected too.
***>
September 05, 2007
Factors Influencing Self-Recovery from Hepatitis C
As reported in the August 21, 2007 edition of the World Journal of
Gastroenterology, researchers investigated why some people are able to
spontaneously recover from the Hepatitis C virus. This study found the
following factors responsible for a person's ability, or inability, to
self-recover from the virus - quantity of Hepatitis C antibody, co-infection
with Hepatitis B, and the active use of IV drugs.
Source: World Journal of Gastroenterology
Date: August 29, 2007
w w w .sciencedaily . com
Who Will Recover Spontaneously From Hepatitis C Virus Infection?
Science Daily - More than 3% of world population is infected with hepatitis
C virus (HCV). The outcome of HCV infections is either self recovery or
chronic hepatitis, and many of the chronic infections will develop into
liver cirrhosis or liver cancer. Since there is no cure for chronic
hepatitis C, nor is there any approved vaccine for this virus, hepatitis C
is currently a major health problem worldwide.
Twenty to fifty percent of HCV infected patients recovers spontaneously. The
hepatitis C patients and their relatives like to know if his/her infection
would fall into the category for self recovery.
A research article to be published on August 21 in the World Journal of
Gastroenterology addresses this question.
The research team led by Dr. Mihm from Georg-August-Universität spent more
than 8 years working with a cohort of 67 patients who spontaneously
recovered from HCV infection. In addition to these, the researchers included
a similar number of patients with chronic HCV infection. Large sample size
allowed these investigators to obtain results with great statistical
significance, and to draw very reliable conclusions.
One conclusion reported by the investigators is, patients who self recovered
usually have lower levels of HCV antibody. Thus patients with lower HCV
antibody titer may have a brighter clinical outcome. However, for a
practical standard to be established to define a low HCV antibody titer,
more effort is needed by investigators in the future.
***>
Another interesting conclusion reached by these investigators is,
co-infection by hepatitis B virus (HBV) is associated with a higher
possibility of self recovery. The investigators suggested that the infection
of HBV interferes with the HCV replication, which would finally lead to
virus eradiacation.. HCV patients co-infected by hepatitis A virus also have
a better chance of self recovery, possibly by a similar mechanism.
***>
Active iv drug users are less likely to self recover, for a couple of
reasons: 1, they have a higher incidence of re-infection; 2, drugs have been
shown to inhibit the expression of antiviral cytokines such as IFN-a and
IFN-g; 3, HCV replication has been shown to be enhanced both by morphine use
and morphine withdrawal.
Several different genotypes of HCV were discovered. The HCV genotype studied
by Dr. Milm¡¯s group is type 1b, which is the prevalent genotype in Germany,
and in China.
Note: This story has been adapted from a news release issued by World
Journal of Gastroenterology.
