Pretreatment total testosterone levels in patients with prostate cancer in Japan

Pretreatment total testosterone levels in patients with prostate cancer in Japan

The just published Japanese study

Sekine Y, Ito K, Yamamoto T, Nakazato H, Shibata Y, Hatori M, Suzuki
K.
Pretreatment total testosterone levels in patients with prostate
cancer in the past two decades in Japan.
Cancer Detect Prev. 2007 Apr 5; [Epub ahead of print]
PMID: 17418977 [PubMed - as supplied by publisher]
< * w w w .ncbi.nlm.nih.gov/entrez/query.fcgi?tmpl=NoSidebarfile&db=PubMed&cmd=Retrieve&list_uids=17418977&dopt=Abstract>

found that patients with poorly differentiated prostate cancer
had lower testosterone levels than the others.

Abstract:

"Background: Many studies have shown the relationship between
pretreatment serum testosterone levels and the clinical stage
or histological grade, but the clinical significance of
pretreatment testosterone levels is controversial. We studied
the association of pretreatment total testosterone levels with
the clinical stage and histological grade of prostate cancer.
Methods: We evaluated 2914 patients whose pretreatment
testosterone levels were recorded from 1982 to 2002. Serum
testosterone levels were measured by radioimmunoassay. Results:
There was a trend toward decreasing testosterone values with
worsening clinical staging. There was a trend toward decreasing
testosterone values with worsening histological grading, too.
Patients with poorly differentiated adenocarcinoma had
significantly lower testosterone levels than those with the
others (versus well; p<0.01, moderately; p<0.01). Conclusions:
Newly diagnosed patients with poorly differentiated
adenocarcinoma of prostate have lower testosterone levels than
the others."


--
Matti Narkia

Re: Pretreatment total testosterone levels in patients with prostate cancer in Japan


"Matti Narkia" <mna@mbnet.fi> wrote in message
news:neao13h76ktcufk3jc7rdh68r9iqn9cpfg@4ax . com ...
> The just published Japanese study
>
> Sekine Y, Ito K, Yamamoto T, Nakazato H, Shibata Y, Hatori M, Suzuki
> K.
> Pretreatment total testosterone levels in patients with prostate
> cancer in the past two decades in Japan.
> Cancer Detect Prev. 2007 Apr 5; [Epub ahead of print]
> PMID: 17418977 [PubMed - as supplied by publisher]
>
< * w w w .ncbi.nlm.nih.gov/entrez/query.fcgi?tmpl=NoSidebarfile&db=PubMed&
cmd=Retrieve&list_uids=17418977&dopt=Abstract>
>
> found that patients with poorly differentiated prostate cancer
> had lower testosterone levels than the others.
>
> Abstract:
>
> "Background: Many studies have shown the relationship between
> pretreatment serum testosterone levels and the clinical stage
> or histological grade, but the clinical significance of
> pretreatment testosterone levels is controversial. We studied
> the association of pretreatment total testosterone levels with
> the clinical stage and histological grade of prostate cancer.
> Methods: We evaluated 2914 patients whose pretreatment
> testosterone levels were recorded from 1982 to 2002. Serum
> testosterone levels were measured by radioimmunoassay. Results:
> There was a trend toward decreasing testosterone values with
> worsening clinical staging. There was a trend toward decreasing
> testosterone values with worsening histological grading, too.
> Patients with poorly differentiated adenocarcinoma had
> significantly lower testosterone levels than those with the
> others (versus well; p<0.01, moderately; p<0.01). Conclusions:
> Newly diagnosed patients with poorly differentiated
> adenocarcinoma of prostate have lower testosterone levels than
> the others."
>
>
> --
> Matti Narkia

very nice;)))
* click.adultsingles . com /partner/click.asp?id=72473&site=ads&typ=click
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at first I was surprised, honestly