Re: S-F Willow Herb - Tincture or Infusion?On Mar 9, 9:47 pm, Bren...@mailinator,com wrote:
> On Mar 9, 8:01 am, "just Ed" <just_ed53s...@yahoo,com > wrote:
>
>
>
> > On Mar 8, 10:27 pm, Bren...@mailinator,com wrote:
>
> > > Small Flowered Willow Herb (Epilobium Parviflorum) - Should I make an
> > > infusion (tea) or tincture? This herb is reportedly effective in
> > > treating both BPH and prostate cancer.
>
> > > I searched google, and all the sites talk about making an infusion,
> > > except one, which described a study which used an alcohol extract of
> > > Epilobium Parviflorum in treating prostate cancer and BPH.
>
> > that study may be PMID: 16122891
> > it says both water and ethanolic extracts showed effect.
>
> > > The important constituants of the herb are Beta-Sistosterol,
> > > Quercetin, and Oenothein B. Are these all water soluble? If I make a
> > > tincture what % alcohol should I use? The general rule seems to be 50%
> > > (100 proof vodka), but this varies based on the herb. With some herbs
> > > tinctures are not recommended. Unfortunately this herb isn't listed on
> > > the sites I checked.
>
> > you don't know what the important constituents are, but they
> > are soluable in water and/or ethanol. Using a water/ethanol
> > mixture means you will dissolve anything that dissolves in either,
> > not as well as each pure liquid.
>
> > > Thanks for any help.
>
> > you really should first verify that you really have any
> > prostate problem at all, brenda.
>
> > pubmed didn't have anything on safety of Epilobium Parviflorum
> > and even if it is safe, by luck, you're going to foul up the taste
> > of some perfectly good vodka.
>
> I found several research articles, only one said they used an alcohol
> extraction. The others didn't specify. The herb inhibits the enzymes
> aromatase and 5-alpha-reductase, both of which are involved in
> prostate enlargement.
PMID: 8778238 says a water extract inhibited 5-AR, I didn't find
anything mentioning aromatase inhibition.
>The herb has been used for prostate problems for
> many years in Europe (for long enought to be considered a "folk"
> remedy)- if there were any problems with it the news would have
> spread.
I don't buy that:
Alcoholic extraction may liberate thousands of times more,
different components than ingestion of traditional herb. Likewise,
water extraction can allow extraction from larger quantities
of herb than can be conveniently ingested. In either case,
use of traditional herb does not represent the dosage,
range of constituents provided by extracts.
> The studies are more recent. The diagnosis here is BPH, not
> cancer. Research has shown Epilobium Parviflorum is as effective as
> Proscar/Finasteride (a synthetic 5-alpha-reductase inhibitor) in
> treating BPH. As a plus - Epilobium sp. has been shown to inhibit the
> spread of prostate cancer.
'Epilobium Parviflorum Finasteride' finds nothing in Pubmed, please
provide that reference if you can.
PMID: 12043098 turns up quickly showing saw palmetto/nettle root
perform as well with "better tolerability than finasteride".
PMID: 10563375 is "Antiproliferative effect of a polysaccharide
fraction of a 20% methanolic extract of stinging nettle roots upon
epithelial cells of the human prostate (LNCaP)."
I don't think I need to comment on saw palmetto, and PMID: 16635963
did 500+ patients to 18 months on Urtica dioica (nettle root) extract
for safety.
bottom line: I don't think Epilobium Parviflorum is as well
researched,
no reason to think its better, inferior safety data... use it only as
a 'later' if not 'last' resort.
I can't find it now, but (from memory) I thought that nettle root
extract
acted by competitive(?) inhibition of an estrogen receptor (thus the
use with saw palmetto). If this is correct, it might complement an
aromatase inhibitor in shutting down that growth mechanism.