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Iron Overload Predicts Infectious Disease
Iron Overload Predicts Infectious Disease
Anyone in the .. sciences .. care to venture a .. "notion" .. why this
would be .. so .. ?
Heh .. heh ..
Int J Infect Dis. 2007 Jun 26; [Epub ahead of print]Links
Association of hemochromatosis with infectious diseases: expanding
spectrum.Khan FA, Fisher MA, Khakoo RA.
Department of Medicine, Section of Infectious Diseases, Ohio Valley
Medical Center, 2000 Eoff Street, Wheeling, WV 26003, USA; Section of
Infectious Diseases, West Virginia University Hospitals, Morgantown,
WV 26506, USA.
Withholding iron from potential pathogens is a host defense strategy.
There is evidence that iron overload per se compromises the ability of
phagocytes to kill microorganisms. Several hypotheses exist to explain
the association of hemochromatosis with infection. A combination of
mechanisms likely contributes to the increase in susceptibility to
infection in these patients. A review of the current literature
delineating various pathogens to which patients with hemochromatosis
are potentially susceptible, and recent advances in the understanding
of the association of hemochromatosis with infection, are discussed.
PMID: 17600748 [PubMed - as supplied by publisher]
Who loves ya.
Tom
Jesus Was A Vegetarian!
* jesuswasavegetarian.7h . com
Man Is A Herbivore!
* tinyurl . com /a3cc3
DEAD PEOPLE WALKING
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Anyone in the .. sciences .. care to venture a .. "notion" .. why this
would be .. so .. ?
Heh .. heh ..
Int J Infect Dis. 2007 Jun 26; [Epub ahead of print]Links
Association of hemochromatosis with infectious diseases: expanding
spectrum.Khan FA, Fisher MA, Khakoo RA.
Department of Medicine, Section of Infectious Diseases, Ohio Valley
Medical Center, 2000 Eoff Street, Wheeling, WV 26003, USA; Section of
Infectious Diseases, West Virginia University Hospitals, Morgantown,
WV 26506, USA.
Withholding iron from potential pathogens is a host defense strategy.
There is evidence that iron overload per se compromises the ability of
phagocytes to kill microorganisms. Several hypotheses exist to explain
the association of hemochromatosis with infection. A combination of
mechanisms likely contributes to the increase in susceptibility to
infection in these patients. A review of the current literature
delineating various pathogens to which patients with hemochromatosis
are potentially susceptible, and recent advances in the understanding
of the association of hemochromatosis with infection, are discussed.
PMID: 17600748 [PubMed - as supplied by publisher]
Who loves ya.
Tom
Jesus Was A Vegetarian!
* jesuswasavegetarian.7h . com
Man Is A Herbivore!
* tinyurl . com /a3cc3
DEAD PEOPLE WALKING
* tinyurl . com /zk9fk
Re: Iron Overload Predicts Infectious Disease
>> On Jul 2, 1:08 pm, "ironjust...@aol . com " <ironjust...@aol . com > wrote:
Anyone in the .. sciences .. care to venture a .. "notion" .. why this
would be .. so .. ? <<
<<snip>>
low serum ferritin levels appeared to protect against persistent
viremia.
<<snip>>
Factors associated with persistence of hepatitis C viremia identified
WESTPORT, Apr 01 (Reuters Health) - Route and timing of exposure to
the
hepatitis C virus appear to affect patients' chances for spontaneous
resolution
of viremia.
In the March issue of the American Journal of Gastroenterology, Dr.
Patrick
G.
Quinn and colleagues at the University of New Mexico School of
Medicine in
Albuquerque, New Mexico, report on a study of 44 patients with
positive
hepatitis C antibody tests in whom virus was undetectable with
polymerase
chain
reaction. The researchers compared these patients to 214 controls
with
persistent hepatitis C viremia.
On multivariate analysis, "...a history of parenteral exposure and a
long
time
interval since the most recent exposure were both associated with an
increased
likelihood of persistent viremia," the authors said. Monogamy and low
serum
ferritin levels appeared to protect against persistent viremia.
Patients with and without persistent viremia were not
different in terms of demographics, concomitant diseases, medical
histories,
blood group or risky health or sexual habits, according to the
authors.
"[O]ur data support the concept that the route of exposure
and the time when the exposure occurred may be important factors in
the
development of persistent [hepatitis C virus] infection," Dr. Quinn's
team
concludes.
"They also suggest that host factors, such as iron stores, may
modulate...outcome. A better understanding of the environmental and
host
factors in the development of chronic...infection will help us to
intervene
in
the spread of this epidemic."
Who loves ya.
Tom
Jesus Was A Vegetarian!
* jesuswasavegetarian.7h . com
Man Is A Herbivore!
* tinyurl . com /a3cc3
DEAD PEOPLE WALKING
* tinyurl . com /zk9fk
>> On Jul 2, 1:08 pm, "ironjust...@aol . com " <ironjust...@aol . com > wrote:
Anyone in the .. sciences .. care to venture a .. "notion" .. why this
would be .. so .. ? <<
<<snip>>
low serum ferritin levels appeared to protect against persistent
viremia.
<<snip>>
Factors associated with persistence of hepatitis C viremia identified
WESTPORT, Apr 01 (Reuters Health) - Route and timing of exposure to
the
hepatitis C virus appear to affect patients' chances for spontaneous
resolution
of viremia.
In the March issue of the American Journal of Gastroenterology, Dr.
Patrick
G.
Quinn and colleagues at the University of New Mexico School of
Medicine in
Albuquerque, New Mexico, report on a study of 44 patients with
positive
hepatitis C antibody tests in whom virus was undetectable with
polymerase
chain
reaction. The researchers compared these patients to 214 controls
with
persistent hepatitis C viremia.
On multivariate analysis, "...a history of parenteral exposure and a
long
time
interval since the most recent exposure were both associated with an
increased
likelihood of persistent viremia," the authors said. Monogamy and low
serum
ferritin levels appeared to protect against persistent viremia.
Patients with and without persistent viremia were not
different in terms of demographics, concomitant diseases, medical
histories,
blood group or risky health or sexual habits, according to the
authors.
"[O]ur data support the concept that the route of exposure
and the time when the exposure occurred may be important factors in
the
development of persistent [hepatitis C virus] infection," Dr. Quinn's
team
concludes.
"They also suggest that host factors, such as iron stores, may
modulate...outcome. A better understanding of the environmental and
host
factors in the development of chronic...infection will help us to
intervene
in
the spread of this epidemic."
Who loves ya.
Tom
Jesus Was A Vegetarian!
* jesuswasavegetarian.7h . com
Man Is A Herbivore!
* tinyurl . com /a3cc3
DEAD PEOPLE WALKING
* tinyurl . com /zk9fk
