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Bisphosphonate For Free / Free Bisphosphonate
Bisphosphonate For Free / Free Bisphosphonate
* w w w .news-medical . net /?id=11842
"There is no evidence currently available to definitely confirm that
one bisphosphonate is better than another, mainly because the
appropriate studies have not been done," he adds.
I would say .. there IS evidence .. one is better than the other ..
mine costs .. nothing.
It is .. free.
-----------------------------------------------
You know there seems to be a bisphosphonate found in your .. grub.
Phytate / phytic acid .. found in the chaff of your grain and in your
plants compared to .. etidronate.
* tinyurl . com /2wuhuk
Who loves ya.
Tom
Jesus Was A Vegetarian!
* jesuswasavegetarian.7h . com
Man Is A Herbivore!
* tinyurl . com /a3cc3
DEAD PEOPLE WALKING
* tinyurl . com /zk9fk
* w w w .news-medical . net /?id=11842
"There is no evidence currently available to definitely confirm that
one bisphosphonate is better than another, mainly because the
appropriate studies have not been done," he adds.
I would say .. there IS evidence .. one is better than the other ..
mine costs .. nothing.
It is .. free.
-----------------------------------------------
You know there seems to be a bisphosphonate found in your .. grub.
Phytate / phytic acid .. found in the chaff of your grain and in your
plants compared to .. etidronate.
* tinyurl . com /2wuhuk
Who loves ya.
Tom
Jesus Was A Vegetarian!
* jesuswasavegetarian.7h . com
Man Is A Herbivore!
* tinyurl . com /a3cc3
DEAD PEOPLE WALKING
* tinyurl . com /zk9fk
Re: Bisphosphonate For Free / Free Bisphosphonate
On Jan 8, 10:40 pm, ironjustice <teamtan...@hotmail . com > wrote:no
evidence currently available to definitely confirm that
> one bisphosphonate is better than another <<
"Osteoporosis, malignancies and rheumatoid arthritis"
Olpadronate: a new amino-bisphosphonate for the treatment of medical
osteopathies
Authors: Roldn E.J.A.1; Prez A.2; Roldn J.L.3
Source: Expert Opinion on Investigational Drugs, Volume 7, Number 9,
September 1998 , pp. 1521-1538(18)
Abstract:
Olpadronate is a nitrogenated bisphosphonate. Although it shares the
therapeutic and pharmacological properties of pamidronate and
alendronate, it has a greater dosage amplitude, more predictable
effects and a greater digestive tolerability than other bisphosphates.
Therefore, it may be more appropriate in the treatment of medical
osteopathies, by both oral and parenteral routes of administration.
According to various experimental and human models, the
pharmacological potency of olpadronate is 5- to 10-times higher than
that of pamidronate and close to that of alendronate. The two methyl
groups bound to the nitrogen atom give the compound a high water
solubility, which is about 8-times higher than that of the two other
bisphosphonates. The lack of a terminal amino group in the side-chain
of the molecule and the absence of crystallised forms of the compound
in the digestive tract (due to its high water solubility) may avoid
the potential for inducing oesophageal and gastrointestinal side-
effects. These features may explain the high tolerability reported
after the administration of doses of olpadronate (by the oral route)
up to 5- to 10-times higher than the maximum tolerated dose of
alendronate in Paget's bone disease and bone metastases, thus widening
the possibilities for its clinical usage. In addition, initial
pharmacokinetic studies suggest that olpadronate's oral
bioavailability would fit into a confidence range of 2 - 4%, which
contrasts with the erratic absorption shown by other highly potent
bisphosphonates. The clinical efficacy demonstrated in preliminary
studies in Paget's bone disease (including ultra-short treatments),
and also in single-dose iv. therapy of hypercalcaemia of malignancies,
renders olpadronate among the most promising bisphosphonate compounds,
with potential use in the treatment of a variety of bone-involving
diseases, such as osteoporosis, malignancies and rheumatoid arthritis.
Keywords: bisphosphates; bone metastasis; bone strength;
hypercalcemia; olpadronate; osteoporosis; Paget's bone disease
Document Type: Miscellaneous
Affiliations: 1: Department of Clinical Pharmacology, Gador SA, Buenos
Aires 2: Department of Clinical Pharmacology, Gador SA, Buenos Aires
3: Center for Metabolic Studies on Calcium and Phosphorus (CEMFOC),
National University of Rosario, Rosario, Argentina
Who loves ya.
Tom
Jesus Was A Vegetarian!
* jesuswasavegetarian.7h . com
Man Is A Herbivore!
* tinyurl . com /a3cc3
DEAD PEOPLE WALKING
* tinyurl . com /zk9fk
> * w w w .news-medical . net /?id=11842
>
> "There is no evidence currently available to definitely confirm that
> one bisphosphonate is better than another, mainly because the
> appropriate studies have not been done," he adds.
>
> I would say .. there IS evidence .. one is better than the other ..
> mine costs .. nothing.
>
> It is .. free.
>
> -----------------------------------------------
>
> You know there seems to be a bisphosphonate found in your .. grub.
>
> Phytate / phytic acid .. found in the chaff of your grain and in your
> plants compared to .. etidronate.
>
> * tinyurl . com /2wuhuk
>
> Who loves ya.
> Tom
>
> Jesus Was A Vegetarian! * jesuswasavegetarian.7h . com
>
> Man Is A Herbivore! * tinyurl . com /a3cc3
>
> DEAD PEOPLE WALKING * tinyurl . com /zk9fk
On Jan 8, 10:40 pm, ironjustice <teamtan...@hotmail . com > wrote:no
evidence currently available to definitely confirm that
> one bisphosphonate is better than another <<
"Osteoporosis, malignancies and rheumatoid arthritis"
Olpadronate: a new amino-bisphosphonate for the treatment of medical
osteopathies
Authors: Roldn E.J.A.1; Prez A.2; Roldn J.L.3
Source: Expert Opinion on Investigational Drugs, Volume 7, Number 9,
September 1998 , pp. 1521-1538(18)
Abstract:
Olpadronate is a nitrogenated bisphosphonate. Although it shares the
therapeutic and pharmacological properties of pamidronate and
alendronate, it has a greater dosage amplitude, more predictable
effects and a greater digestive tolerability than other bisphosphates.
Therefore, it may be more appropriate in the treatment of medical
osteopathies, by both oral and parenteral routes of administration.
According to various experimental and human models, the
pharmacological potency of olpadronate is 5- to 10-times higher than
that of pamidronate and close to that of alendronate. The two methyl
groups bound to the nitrogen atom give the compound a high water
solubility, which is about 8-times higher than that of the two other
bisphosphonates. The lack of a terminal amino group in the side-chain
of the molecule and the absence of crystallised forms of the compound
in the digestive tract (due to its high water solubility) may avoid
the potential for inducing oesophageal and gastrointestinal side-
effects. These features may explain the high tolerability reported
after the administration of doses of olpadronate (by the oral route)
up to 5- to 10-times higher than the maximum tolerated dose of
alendronate in Paget's bone disease and bone metastases, thus widening
the possibilities for its clinical usage. In addition, initial
pharmacokinetic studies suggest that olpadronate's oral
bioavailability would fit into a confidence range of 2 - 4%, which
contrasts with the erratic absorption shown by other highly potent
bisphosphonates. The clinical efficacy demonstrated in preliminary
studies in Paget's bone disease (including ultra-short treatments),
and also in single-dose iv. therapy of hypercalcaemia of malignancies,
renders olpadronate among the most promising bisphosphonate compounds,
with potential use in the treatment of a variety of bone-involving
diseases, such as osteoporosis, malignancies and rheumatoid arthritis.
Keywords: bisphosphates; bone metastasis; bone strength;
hypercalcemia; olpadronate; osteoporosis; Paget's bone disease
Document Type: Miscellaneous
Affiliations: 1: Department of Clinical Pharmacology, Gador SA, Buenos
Aires 2: Department of Clinical Pharmacology, Gador SA, Buenos Aires
3: Center for Metabolic Studies on Calcium and Phosphorus (CEMFOC),
National University of Rosario, Rosario, Argentina
Who loves ya.
Tom
Jesus Was A Vegetarian!
* jesuswasavegetarian.7h . com
Man Is A Herbivore!
* tinyurl . com /a3cc3
DEAD PEOPLE WALKING
* tinyurl . com /zk9fk
> * w w w .news-medical . net /?id=11842
>
> "There is no evidence currently available to definitely confirm that
> one bisphosphonate is better than another, mainly because the
> appropriate studies have not been done," he adds.
>
> I would say .. there IS evidence .. one is better than the other ..
> mine costs .. nothing.
>
> It is .. free.
>
> -----------------------------------------------
>
> You know there seems to be a bisphosphonate found in your .. grub.
>
> Phytate / phytic acid .. found in the chaff of your grain and in your
> plants compared to .. etidronate.
>
> * tinyurl . com /2wuhuk
>
> Who loves ya.
> Tom
>
> Jesus Was A Vegetarian! * jesuswasavegetarian.7h . com
>
> Man Is A Herbivore! * tinyurl . com /a3cc3
>
> DEAD PEOPLE WALKING * tinyurl . com /zk9fk
Re: Bisphosphonate For Free / Free Bisphosphonate
On Jan 8, 11:08 pm, ironjustice <teamtan...@hotmail . com > wrote:You
know there seems to be a bisphosphonate found in your .. grub. <<
Science Strongly Reaffirms Oatmeal's Health Claims
Main Category: Cholesterol
Also Included In: Nutrition / Diet; Obesity / Weight Loss / Fitness;
Hypertension
Article Date: 09 Jan 2008 - 2:00 PST
A new scientific review of the most current research shows the link
between eating oatmeal and cholesterol reduction to be stronger than
when the FDA initially approved the health claim's appearance on food
labels in 1997.
Dr. James W. Anderson, professor of medicine and clinical nutrition at
the University of Kentucky College of Medicine, co-authors "The
Oatmeal-Cholesterol Connection: 10 Years Later" in the January/
February 2008 issue of the American Journal of Lifestyle Medicine.
Anderson presents a contemporary analysis to determine if newer
studies are consistent with the original conclusion reached by the
FDA. His report says studies conducted during the past 15 years have,
without exception, shown:
* total cholesterol levels are lowered through oat consumption;
* low-density lipoprotein (LDL, the "bad" cholesterol) is reduced
without adverse effects on high-density lipoprotein cholesterol (HDL,
the "good" cholesterol), or triglyceride concentrations.
"Whole-grain products like oatmeal are among some of the best foods
one can eat to improve cholesterol levels, in addition to other
lifestyle choices," Anderson said. "Lifestyle choices, such as diet,
should be the first line of therapy for most patients with moderate
cholesterol risk given the expense, safety concerns, and intolerance
related to cholesterol lowering drugs."
More recent data indicate that whole-grain oats, as part of a
lifestyle management program, may confer health benefits that extend
beyond total cholesterol and LDL cholesterol reduction, Anderson
said.
Recent studies suggest eating oatmeal may:
* Reduce the risk for elevated blood pressure, Type 2 diabetes, and
weight gain
* Reduce LDL cholesterol during weight-loss
* Provide favorable changes in the physical characteristics of LDL
cholesterol particles, making them less susceptible to oxidation
(oxidation is thought to lead to hardening of the arteries.)
* Supply unique compounds that may lead to reducing early hardening of
the arteries
"Since the 80's, oatmeal has been scientifically recognized for its
heart health benefits, and the latest research shows this evidence
endures the test of time and should be embraced as a lifestyle option
for the millions of Americans at-risk for heart disease," said
Anderson.
Anderson co-authored the comprehensive research review with Mark
Andon, a researcher and nutrition director for Quaker-Tropicana.
In striving to become a Top 20 public research institution, the
University of Kentucky is a catalyst for a new Commonwealth - a
Kentucky that is healthier, better educated, and positioned to compete
in a global and changing economy. For more information about UK's
efforts to become a Top 20 university, please go to * w w w .uky.edu/OPBPA=
/Top20.html.
Source: Amanda Nelson
University of Kentucky
Who loves ya.
Tom
Jesus Was A Vegetarian!
* jesuswasavegetarian.7h . com
Man Is A Herbivore!
* tinyurl . com /a3cc3
DEAD PEOPLE WALKING
* tinyurl . com /zk9fk
> On Jan 8, 10:40 pm, ironjustice <teamtan...@hotmail . com > wrote:no
> evidence currently available to definitely confirm that
>
> > one bisphosphonate is better than another <<
>
> "Osteoporosis, malignancies and rheumatoid arthritis"
>
> Olpadronate: a new amino-bisphosphonate for the treatment of medical
> osteopathies
> Authors: Roldn E.J.A.1; Prez A.2; Roldn J.L.3
>
> Source: Expert Opinion on Investigational Drugs, Volume 7, Number 9,
> September 1998 , pp. 1521-1538(18)
>
> Abstract:
>
> Olpadronate is a nitrogenated bisphosphonate. Although it shares the
> therapeutic and pharmacological properties of pamidronate and
> alendronate, it has a greater dosage amplitude, more predictable
> effects and a greater digestive tolerability than other bisphosphates.
> Therefore, it may be more appropriate in the treatment of medical
> osteopathies, by both oral and parenteral routes of administration.
> According to various experimental and human models, the
> pharmacological potency of olpadronate is 5- to 10-times higher than
> that of pamidronate and close to that of alendronate. The two methyl
> groups bound to the nitrogen atom give the compound a high water
> solubility, which is about 8-times higher than that of the two other
> bisphosphonates. The lack of a terminal amino group in the side-chain
> of the molecule and the absence of crystallised forms of the compound
> in the digestive tract (due to its high water solubility) may avoid
> the potential for inducing oesophageal and gastrointestinal side-
> effects. These features may explain the high tolerability reported
> after the administration of doses of olpadronate (by the oral route)
> up to 5- to 10-times higher than the maximum tolerated dose of
> alendronate in Paget's bone disease and bone metastases, thus widening
> the possibilities for its clinical usage. In addition, initial
> pharmacokinetic studies suggest that olpadronate's oral
> bioavailability would fit into a confidence range of 2 - 4%, which
> contrasts with the erratic absorption shown by other highly potent
> bisphosphonates. The clinical efficacy demonstrated in preliminary
> studies in Paget's bone disease (including ultra-short treatments),
> and also in single-dose iv. therapy of hypercalcaemia of malignancies,
> renders olpadronate among the most promising bisphosphonate compounds,
> with potential use in the treatment of a variety of bone-involving
> diseases, such as osteoporosis, malignancies and rheumatoid arthritis.
>
> Keywords: bisphosphates; bone metastasis; bone strength;
> hypercalcemia; olpadronate; osteoporosis; Paget's bone disease
>
> Document Type: Miscellaneous
>
> Affiliations: 1: Department of Clinical Pharmacology, Gador SA, Buenos
> Aires 2: Department of Clinical Pharmacology, Gador SA, Buenos Aires
> 3: Center for Metabolic Studies on Calcium and Phosphorus (CEMFOC),
> National University of Rosario, Rosario, Argentina
>
> Who loves ya.
> Tom
>
> Jesus Was A Vegetarian! * jesuswasavegetarian.7h . com
>
> Man Is A Herbivore! * tinyurl . com /a3cc3
>
> DEAD PEOPLE WALKING * tinyurl . com /zk9fk
>
>
>
> > * w w w .news-medical . net /?id=11842
>
> > "There is no evidence currently available to definitely confirm that
> > one bisphosphonate is better than another, mainly because the
> > appropriate studies have not been done," he adds.
>
> > I would say .. there IS evidence .. one is better than the other ..
> > mine costs .. nothing.
>
> > It is .. free.
>
> > -----------------------------------------------
>
> > You know there seems to be a bisphosphonate found in your .. grub.
>
> > Phytate / phytic acid .. found in the chaff of your grain and in your
> > plants compared to .. etidronate.
>
> > * tinyurl . com /2wuhuk
>
> > Who loves ya.
> > Tom
>
> > Jesus Was A Vegetarian! * jesuswasavegetarian.7h . com
>
> > Man Is A Herbivore! * tinyurl . com /a3cc3
>
> > DEAD PEOPLE WALKING * tinyurl . com /zk9fk- Hide quoted text -
>
> - Show quoted text -
On Jan 8, 11:08 pm, ironjustice <teamtan...@hotmail . com > wrote:You
know there seems to be a bisphosphonate found in your .. grub. <<
Science Strongly Reaffirms Oatmeal's Health Claims
Main Category: Cholesterol
Also Included In: Nutrition / Diet; Obesity / Weight Loss / Fitness;
Hypertension
Article Date: 09 Jan 2008 - 2:00 PST
A new scientific review of the most current research shows the link
between eating oatmeal and cholesterol reduction to be stronger than
when the FDA initially approved the health claim's appearance on food
labels in 1997.
Dr. James W. Anderson, professor of medicine and clinical nutrition at
the University of Kentucky College of Medicine, co-authors "The
Oatmeal-Cholesterol Connection: 10 Years Later" in the January/
February 2008 issue of the American Journal of Lifestyle Medicine.
Anderson presents a contemporary analysis to determine if newer
studies are consistent with the original conclusion reached by the
FDA. His report says studies conducted during the past 15 years have,
without exception, shown:
* total cholesterol levels are lowered through oat consumption;
* low-density lipoprotein (LDL, the "bad" cholesterol) is reduced
without adverse effects on high-density lipoprotein cholesterol (HDL,
the "good" cholesterol), or triglyceride concentrations.
"Whole-grain products like oatmeal are among some of the best foods
one can eat to improve cholesterol levels, in addition to other
lifestyle choices," Anderson said. "Lifestyle choices, such as diet,
should be the first line of therapy for most patients with moderate
cholesterol risk given the expense, safety concerns, and intolerance
related to cholesterol lowering drugs."
More recent data indicate that whole-grain oats, as part of a
lifestyle management program, may confer health benefits that extend
beyond total cholesterol and LDL cholesterol reduction, Anderson
said.
Recent studies suggest eating oatmeal may:
* Reduce the risk for elevated blood pressure, Type 2 diabetes, and
weight gain
* Reduce LDL cholesterol during weight-loss
* Provide favorable changes in the physical characteristics of LDL
cholesterol particles, making them less susceptible to oxidation
(oxidation is thought to lead to hardening of the arteries.)
* Supply unique compounds that may lead to reducing early hardening of
the arteries
"Since the 80's, oatmeal has been scientifically recognized for its
heart health benefits, and the latest research shows this evidence
endures the test of time and should be embraced as a lifestyle option
for the millions of Americans at-risk for heart disease," said
Anderson.
Anderson co-authored the comprehensive research review with Mark
Andon, a researcher and nutrition director for Quaker-Tropicana.
In striving to become a Top 20 public research institution, the
University of Kentucky is a catalyst for a new Commonwealth - a
Kentucky that is healthier, better educated, and positioned to compete
in a global and changing economy. For more information about UK's
efforts to become a Top 20 university, please go to * w w w .uky.edu/OPBPA=
/Top20.html.
Source: Amanda Nelson
University of Kentucky
Who loves ya.
Tom
Jesus Was A Vegetarian!
* jesuswasavegetarian.7h . com
Man Is A Herbivore!
* tinyurl . com /a3cc3
DEAD PEOPLE WALKING
* tinyurl . com /zk9fk
> On Jan 8, 10:40 pm, ironjustice <teamtan...@hotmail . com > wrote:no
> evidence currently available to definitely confirm that
>
> > one bisphosphonate is better than another <<
>
> "Osteoporosis, malignancies and rheumatoid arthritis"
>
> Olpadronate: a new amino-bisphosphonate for the treatment of medical
> osteopathies
> Authors: Roldn E.J.A.1; Prez A.2; Roldn J.L.3
>
> Source: Expert Opinion on Investigational Drugs, Volume 7, Number 9,
> September 1998 , pp. 1521-1538(18)
>
> Abstract:
>
> Olpadronate is a nitrogenated bisphosphonate. Although it shares the
> therapeutic and pharmacological properties of pamidronate and
> alendronate, it has a greater dosage amplitude, more predictable
> effects and a greater digestive tolerability than other bisphosphates.
> Therefore, it may be more appropriate in the treatment of medical
> osteopathies, by both oral and parenteral routes of administration.
> According to various experimental and human models, the
> pharmacological potency of olpadronate is 5- to 10-times higher than
> that of pamidronate and close to that of alendronate. The two methyl
> groups bound to the nitrogen atom give the compound a high water
> solubility, which is about 8-times higher than that of the two other
> bisphosphonates. The lack of a terminal amino group in the side-chain
> of the molecule and the absence of crystallised forms of the compound
> in the digestive tract (due to its high water solubility) may avoid
> the potential for inducing oesophageal and gastrointestinal side-
> effects. These features may explain the high tolerability reported
> after the administration of doses of olpadronate (by the oral route)
> up to 5- to 10-times higher than the maximum tolerated dose of
> alendronate in Paget's bone disease and bone metastases, thus widening
> the possibilities for its clinical usage. In addition, initial
> pharmacokinetic studies suggest that olpadronate's oral
> bioavailability would fit into a confidence range of 2 - 4%, which
> contrasts with the erratic absorption shown by other highly potent
> bisphosphonates. The clinical efficacy demonstrated in preliminary
> studies in Paget's bone disease (including ultra-short treatments),
> and also in single-dose iv. therapy of hypercalcaemia of malignancies,
> renders olpadronate among the most promising bisphosphonate compounds,
> with potential use in the treatment of a variety of bone-involving
> diseases, such as osteoporosis, malignancies and rheumatoid arthritis.
>
> Keywords: bisphosphates; bone metastasis; bone strength;
> hypercalcemia; olpadronate; osteoporosis; Paget's bone disease
>
> Document Type: Miscellaneous
>
> Affiliations: 1: Department of Clinical Pharmacology, Gador SA, Buenos
> Aires 2: Department of Clinical Pharmacology, Gador SA, Buenos Aires
> 3: Center for Metabolic Studies on Calcium and Phosphorus (CEMFOC),
> National University of Rosario, Rosario, Argentina
>
> Who loves ya.
> Tom
>
> Jesus Was A Vegetarian! * jesuswasavegetarian.7h . com
>
> Man Is A Herbivore! * tinyurl . com /a3cc3
>
> DEAD PEOPLE WALKING * tinyurl . com /zk9fk
>
>
>
> > * w w w .news-medical . net /?id=11842
>
> > "There is no evidence currently available to definitely confirm that
> > one bisphosphonate is better than another, mainly because the
> > appropriate studies have not been done," he adds.
>
> > I would say .. there IS evidence .. one is better than the other ..
> > mine costs .. nothing.
>
> > It is .. free.
>
> > -----------------------------------------------
>
> > You know there seems to be a bisphosphonate found in your .. grub.
>
> > Phytate / phytic acid .. found in the chaff of your grain and in your
> > plants compared to .. etidronate.
>
> > * tinyurl . com /2wuhuk
>
> > Who loves ya.
> > Tom
>
> > Jesus Was A Vegetarian! * jesuswasavegetarian.7h . com
>
> > Man Is A Herbivore! * tinyurl . com /a3cc3
>
> > DEAD PEOPLE WALKING * tinyurl . com /zk9fk- Hide quoted text -
>
> - Show quoted text -
Re: Bisphosphonate For Free / Free Bisphosphonate
On Jan 9, 6:14 am, ironjustice <teamtan...@hotmail . com > wrote:there
seems to be a bisphosphonate found in your .. grub. <<
I guess the way this works is .. 'someone' .. will attempt to patent /
disallow this use of this .. substance for the treatment / use AS a
bisphosphonate .. and this is ONLY prevented .. by .. ? ..
Publication .. for .. freeee .. use .. OF .. 'idea' ..
Sooo .. anyone now should be able to claim when they sell you brown
rice .. they can say .. "cancer killer" ..
Phytate has been shown to be a bisphosphonate .. and therefore should
be used as a .. bisphosphonate .. and therefore CAN be used AS a
bisphosphonate ..
Can be used by ANYONE .. for the use as a .. bisphosphonate ..
Did I miss anything .. ?
I think everyone knows then .. that .. phytate found in your food is
a .. free bisphosphonate .. ?
Who loves ya.
Tom
Jesus Was A Vegetarian!
* jesuswasavegetarian.7h . com
Man Is A Herbivore!
* tinyurl . com /a3cc3
DEAD PEOPLE WALKING
* tinyurl . com /zk9fk
> On Jan 8, 11:08 pm, ironjustice <teamtan...@hotmail . com > wrote:You
> know there seems to be a bisphosphonate found in your .. grub. <<
>
> Science Strongly Reaffirms Oatmeal's Health Claims
> Main Category: Cholesterol
> Also Included In: Nutrition / Diet; Obesity / Weight Loss / Fitness;
> Hypertension
> Article Date: 09 Jan 2008 - 2:00 PST
>
> A new scientific review of the most current research shows the link
> between eating oatmeal and cholesterol reduction to be stronger than
> when the FDA initially approved the health claim's appearance on food
> labels in 1997.
>
> Dr. James W. Anderson, professor of medicine and clinical nutrition at
> the University of Kentucky College of Medicine, co-authors "The
> Oatmeal-Cholesterol Connection: 10 Years Later" in the January/
> February 2008 issue of the American Journal of Lifestyle Medicine.
>
> Anderson presents a contemporary analysis to determine if newer
> studies are consistent with the original conclusion reached by the
> FDA. His report says studies conducted during the past 15 years have,
> without exception, shown:
>
> * total cholesterol levels are lowered through oat consumption;
>
> * low-density lipoprotein (LDL, the "bad" cholesterol) is reduced
> without adverse effects on high-density lipoprotein cholesterol (HDL,
> the "good" cholesterol), or triglyceride concentrations.
>
> "Whole-grain products like oatmeal are among some of the best foods
> one can eat to improve cholesterol levels, in addition to other
> lifestyle choices," Anderson said. "Lifestyle choices, such as diet,
> should be the first line of therapy for most patients with moderate
> cholesterol risk given the expense, safety concerns, and intolerance
> related to cholesterol lowering drugs."
>
> More recent data indicate that whole-grain oats, as part of a
> lifestyle management program, may confer health benefits that extend
> beyond total cholesterol and LDL cholesterol reduction, Anderson
> said.
>
> Recent studies suggest eating oatmeal may:
>
> * Reduce the risk for elevated blood pressure, Type 2 diabetes, and
> weight gain
>
> * Reduce LDL cholesterol during weight-loss
>
> * Provide favorable changes in the physical characteristics of LDL
> cholesterol particles, making them less susceptible to oxidation
> (oxidation is thought to lead to hardening of the arteries.)
>
> * Supply unique compounds that may lead to reducing early hardening of
> the arteries
>
> "Since the 80's, oatmeal has been scientifically recognized for its
> heart health benefits, and the latest research shows this evidence
> endures the test of time and should be embraced as a lifestyle option
> for the millions of Americans at-risk for heart disease," said
> Anderson.
>
> Anderson co-authored the comprehensive research review with Mark
> Andon, a researcher and nutrition director for Quaker-Tropicana.
>
> In striving to become a Top 20 public research institution, the
> University of Kentucky is a catalyst for a new Commonwealth - a
> Kentucky that is healthier, better educated, and positioned to compete
> in a global and changing economy. For more information about UK's
> efforts to become a Top 20 university, please go to * w w w .uky.edu/OPBP=
A/Top20.html.
>
> Source: Amanda Nelson
> University of Kentucky
>
> Who loves ya.
> Tom
>
> Jesus Was A Vegetarian! * jesuswasavegetarian.7h . com
>
> Man Is A Herbivore! * tinyurl . com /a3cc3
>
> DEAD PEOPLE WALKING * tinyurl . com /zk9fk
>
>
>
> > On Jan 8, 10:40 pm, ironjustice <teamtan...@hotmail . com > wrote:no
> > evidence currently available to definitely confirm that
>
> > > one bisphosphonate is better than another <<
>
> > "Osteoporosis, malignancies and rheumatoid arthritis"
>
> > Olpadronate: a new amino-bisphosphonate for the treatment of medical
> > osteopathies
> > Authors: Roldn E.J.A.1; Prez A.2; Roldn J.L.3
>
> > Source: Expert Opinion on Investigational Drugs, Volume 7, Number 9,
> > September 1998 , pp. 1521-1538(18)
>
> > Abstract:
>
> > Olpadronate is a nitrogenated bisphosphonate. Although it shares the
> > therapeutic and pharmacological properties of pamidronate and
> > alendronate, it has a greater dosage amplitude, more predictable
> > effects and a greater digestive tolerability than other bisphosphates.
> > Therefore, it may be more appropriate in the treatment of medical
> > osteopathies, by both oral and parenteral routes of administration.
> > According to various experimental and human models, the
> > pharmacological potency of olpadronate is 5- to 10-times higher than
> > that of pamidronate and close to that of alendronate. The two methyl
> > groups bound to the nitrogen atom give the compound a high water
> > solubility, which is about 8-times higher than that of the two other
> > bisphosphonates. The lack of a terminal amino group in the side-chain
> > of the molecule and the absence of crystallised forms of the compound
> > in the digestive tract (due to its high water solubility) may avoid
> > the potential for inducing oesophageal and gastrointestinal side-
> > effects. These features may explain the high tolerability reported
> > after the administration of doses of olpadronate (by the oral route)
> > up to 5- to 10-times higher than the maximum tolerated dose of
> > alendronate in Paget's bone disease and bone metastases, thus widening
> > the possibilities for its clinical usage. In addition, initial
> > pharmacokinetic studies suggest that olpadronate's oral
> > bioavailability would fit into a confidence range of 2 - 4%, which
> > contrasts with the erratic absorption shown by other highly potent
> > bisphosphonates. The clinical efficacy demonstrated in preliminary
> > studies in Paget's bone disease (including ultra-short treatments),
> > and also in single-dose iv. therapy of hypercalcaemia of malignancies,
> > renders olpadronate among the most promising bisphosphonate compounds,
> > with potential use in the treatment of a variety of bone-involving
> > diseases, such as osteoporosis, malignancies and rheumatoid arthritis.
>
> > Keywords: bisphosphates; bone metastasis; bone strength;
> > hypercalcemia; olpadronate; osteoporosis; Paget's bone disease
>
> > Document Type: Miscellaneous
>
> > Affiliations: 1: Department of Clinical Pharmacology, Gador SA, Buenos
> > Aires 2: Department of Clinical Pharmacology, Gador SA, Buenos Aires
> > 3: Center for Metabolic Studies on Calcium and Phosphorus (CEMFOC),
> > National University of Rosario, Rosario, Argentina
>
> > Who loves ya.
> > Tom
>
> > Jesus Was A Vegetarian! * jesuswasavegetarian.7h . com
>
> > Man Is A Herbivore! * tinyurl . com /a3cc3
>
> > DEAD PEOPLE WALKING * tinyurl . com /zk9fk
>
> > > * w w w .news-medical . net /?id=11842
>
> > > "There is no evidence currently available to definitely confirm that
> > > one bisphosphonate is better than another, mainly because the
> > > appropriate studies have not been done," he adds.
>
> > > I would say .. there IS evidence .. one is better than the other ..
> > > mine costs .. nothing.
>
> > > It is .. free.
>
> > > -----------------------------------------------
>
> > > You know there seems to be a bisphosphonate found in your .. grub.
>
> > > Phytate / phytic acid .. found in the chaff of your grain and in your
> > > plants compared to .. etidronate.
>
> > > * tinyurl . com /2wuhuk
>
> > > Who loves ya.
> > > Tom
>
> > > Jesus Was A Vegetarian! * jesuswasavegetarian.7h . com
>
> > > Man Is A Herbivore! * tinyurl . com /a3cc3
>
> > > DEAD PEOPLE WALKING * tinyurl . com /zk9fk-Hide quoted text -
>
> > - Show quoted text -- Hide quoted text -
>
> - Show quoted text -
On Jan 9, 6:14 am, ironjustice <teamtan...@hotmail . com > wrote:there
seems to be a bisphosphonate found in your .. grub. <<
I guess the way this works is .. 'someone' .. will attempt to patent /
disallow this use of this .. substance for the treatment / use AS a
bisphosphonate .. and this is ONLY prevented .. by .. ? ..
Publication .. for .. freeee .. use .. OF .. 'idea' ..
Sooo .. anyone now should be able to claim when they sell you brown
rice .. they can say .. "cancer killer" ..
Phytate has been shown to be a bisphosphonate .. and therefore should
be used as a .. bisphosphonate .. and therefore CAN be used AS a
bisphosphonate ..
Can be used by ANYONE .. for the use as a .. bisphosphonate ..
Did I miss anything .. ?
I think everyone knows then .. that .. phytate found in your food is
a .. free bisphosphonate .. ?
Who loves ya.
Tom
Jesus Was A Vegetarian!
* jesuswasavegetarian.7h . com
Man Is A Herbivore!
* tinyurl . com /a3cc3
DEAD PEOPLE WALKING
* tinyurl . com /zk9fk
> On Jan 8, 11:08 pm, ironjustice <teamtan...@hotmail . com > wrote:You
> know there seems to be a bisphosphonate found in your .. grub. <<
>
> Science Strongly Reaffirms Oatmeal's Health Claims
> Main Category: Cholesterol
> Also Included In: Nutrition / Diet; Obesity / Weight Loss / Fitness;
> Hypertension
> Article Date: 09 Jan 2008 - 2:00 PST
>
> A new scientific review of the most current research shows the link
> between eating oatmeal and cholesterol reduction to be stronger than
> when the FDA initially approved the health claim's appearance on food
> labels in 1997.
>
> Dr. James W. Anderson, professor of medicine and clinical nutrition at
> the University of Kentucky College of Medicine, co-authors "The
> Oatmeal-Cholesterol Connection: 10 Years Later" in the January/
> February 2008 issue of the American Journal of Lifestyle Medicine.
>
> Anderson presents a contemporary analysis to determine if newer
> studies are consistent with the original conclusion reached by the
> FDA. His report says studies conducted during the past 15 years have,
> without exception, shown:
>
> * total cholesterol levels are lowered through oat consumption;
>
> * low-density lipoprotein (LDL, the "bad" cholesterol) is reduced
> without adverse effects on high-density lipoprotein cholesterol (HDL,
> the "good" cholesterol), or triglyceride concentrations.
>
> "Whole-grain products like oatmeal are among some of the best foods
> one can eat to improve cholesterol levels, in addition to other
> lifestyle choices," Anderson said. "Lifestyle choices, such as diet,
> should be the first line of therapy for most patients with moderate
> cholesterol risk given the expense, safety concerns, and intolerance
> related to cholesterol lowering drugs."
>
> More recent data indicate that whole-grain oats, as part of a
> lifestyle management program, may confer health benefits that extend
> beyond total cholesterol and LDL cholesterol reduction, Anderson
> said.
>
> Recent studies suggest eating oatmeal may:
>
> * Reduce the risk for elevated blood pressure, Type 2 diabetes, and
> weight gain
>
> * Reduce LDL cholesterol during weight-loss
>
> * Provide favorable changes in the physical characteristics of LDL
> cholesterol particles, making them less susceptible to oxidation
> (oxidation is thought to lead to hardening of the arteries.)
>
> * Supply unique compounds that may lead to reducing early hardening of
> the arteries
>
> "Since the 80's, oatmeal has been scientifically recognized for its
> heart health benefits, and the latest research shows this evidence
> endures the test of time and should be embraced as a lifestyle option
> for the millions of Americans at-risk for heart disease," said
> Anderson.
>
> Anderson co-authored the comprehensive research review with Mark
> Andon, a researcher and nutrition director for Quaker-Tropicana.
>
> In striving to become a Top 20 public research institution, the
> University of Kentucky is a catalyst for a new Commonwealth - a
> Kentucky that is healthier, better educated, and positioned to compete
> in a global and changing economy. For more information about UK's
> efforts to become a Top 20 university, please go to * w w w .uky.edu/OPBP=
A/Top20.html.
>
> Source: Amanda Nelson
> University of Kentucky
>
> Who loves ya.
> Tom
>
> Jesus Was A Vegetarian! * jesuswasavegetarian.7h . com
>
> Man Is A Herbivore! * tinyurl . com /a3cc3
>
> DEAD PEOPLE WALKING * tinyurl . com /zk9fk
>
>
>
> > On Jan 8, 10:40 pm, ironjustice <teamtan...@hotmail . com > wrote:no
> > evidence currently available to definitely confirm that
>
> > > one bisphosphonate is better than another <<
>
> > "Osteoporosis, malignancies and rheumatoid arthritis"
>
> > Olpadronate: a new amino-bisphosphonate for the treatment of medical
> > osteopathies
> > Authors: Roldn E.J.A.1; Prez A.2; Roldn J.L.3
>
> > Source: Expert Opinion on Investigational Drugs, Volume 7, Number 9,
> > September 1998 , pp. 1521-1538(18)
>
> > Abstract:
>
> > Olpadronate is a nitrogenated bisphosphonate. Although it shares the
> > therapeutic and pharmacological properties of pamidronate and
> > alendronate, it has a greater dosage amplitude, more predictable
> > effects and a greater digestive tolerability than other bisphosphates.
> > Therefore, it may be more appropriate in the treatment of medical
> > osteopathies, by both oral and parenteral routes of administration.
> > According to various experimental and human models, the
> > pharmacological potency of olpadronate is 5- to 10-times higher than
> > that of pamidronate and close to that of alendronate. The two methyl
> > groups bound to the nitrogen atom give the compound a high water
> > solubility, which is about 8-times higher than that of the two other
> > bisphosphonates. The lack of a terminal amino group in the side-chain
> > of the molecule and the absence of crystallised forms of the compound
> > in the digestive tract (due to its high water solubility) may avoid
> > the potential for inducing oesophageal and gastrointestinal side-
> > effects. These features may explain the high tolerability reported
> > after the administration of doses of olpadronate (by the oral route)
> > up to 5- to 10-times higher than the maximum tolerated dose of
> > alendronate in Paget's bone disease and bone metastases, thus widening
> > the possibilities for its clinical usage. In addition, initial
> > pharmacokinetic studies suggest that olpadronate's oral
> > bioavailability would fit into a confidence range of 2 - 4%, which
> > contrasts with the erratic absorption shown by other highly potent
> > bisphosphonates. The clinical efficacy demonstrated in preliminary
> > studies in Paget's bone disease (including ultra-short treatments),
> > and also in single-dose iv. therapy of hypercalcaemia of malignancies,
> > renders olpadronate among the most promising bisphosphonate compounds,
> > with potential use in the treatment of a variety of bone-involving
> > diseases, such as osteoporosis, malignancies and rheumatoid arthritis.
>
> > Keywords: bisphosphates; bone metastasis; bone strength;
> > hypercalcemia; olpadronate; osteoporosis; Paget's bone disease
>
> > Document Type: Miscellaneous
>
> > Affiliations: 1: Department of Clinical Pharmacology, Gador SA, Buenos
> > Aires 2: Department of Clinical Pharmacology, Gador SA, Buenos Aires
> > 3: Center for Metabolic Studies on Calcium and Phosphorus (CEMFOC),
> > National University of Rosario, Rosario, Argentina
>
> > Who loves ya.
> > Tom
>
> > Jesus Was A Vegetarian! * jesuswasavegetarian.7h . com
>
> > Man Is A Herbivore! * tinyurl . com /a3cc3
>
> > DEAD PEOPLE WALKING * tinyurl . com /zk9fk
>
> > > * w w w .news-medical . net /?id=11842
>
> > > "There is no evidence currently available to definitely confirm that
> > > one bisphosphonate is better than another, mainly because the
> > > appropriate studies have not been done," he adds.
>
> > > I would say .. there IS evidence .. one is better than the other ..
> > > mine costs .. nothing.
>
> > > It is .. free.
>
> > > -----------------------------------------------
>
> > > You know there seems to be a bisphosphonate found in your .. grub.
>
> > > Phytate / phytic acid .. found in the chaff of your grain and in your
> > > plants compared to .. etidronate.
>
> > > * tinyurl . com /2wuhuk
>
> > > Who loves ya.
> > > Tom
>
> > > Jesus Was A Vegetarian! * jesuswasavegetarian.7h . com
>
> > > Man Is A Herbivore! * tinyurl . com /a3cc3
>
> > > DEAD PEOPLE WALKING * tinyurl . com /zk9fk-Hide quoted text -
>
> > - Show quoted text -- Hide quoted text -
>
> - Show quoted text -
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