Group: sci.med.diseases.osteoporosis

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Strontium For Osteoporosis

Reply from: BoneLady
Date: 23 Apr, 17:51
Are you interested in an alternative to prescription drugs for
osteoporosis? Strontium builds stronger bones than drugs like Fosamax,
Actonel, or Boniva but without the dangerous side effects. For more
information about strontium for treating osteoporosis, please visit
Strontium For Bones at http://strontiumforbones.blogspot.com/. My
blog offers visitors discussions, information, and links which will be
updated periodically.

Reply from: trigonometry1972@gmail.com |
Date: 23 Apr, 19:36
> On Apr 23, 8:51 am, BoneLady <srsuppor...@gmail.com> wrote:
> Are you interested in an alternative to prescription drugs for
> osteoporosis? Strontium builds stronger bones than drugs like Fosamax,
> Actonel, or Boniva but without the dangerous side effects. For more
> information about strontium for treating osteoporosis, please visit
> Strontium For Bones athttp://strontiumforbones.blogspot.com/.  My
> blog offers visitors discussions, information, and links which will be
> updated periodically

The blog took too long download when I wanted to comment for impatient
me.
The blog mentions also taking 1200 mg of calcium, 500 mg of Magnesium,
and a 1000 IU of D.

I'll suggest you use some other form than magnesium oxide as it
has quite poor absorbed out of the gut. Citrate or even sulfate
forms are better absorbed. Split the dose 3 or 4 ways to avoid
loose bowels.

Don't assume a 1000 IU of D is enough. If you are made of
money have your late winter serum value checked as the
is likely your yearly nadir value for 25 OH vitamin D.
Choose vitamin D3 especially if you are taking large
loading dose. The body doesn't hang on to the so-called
vitamin D2 (really analog to what is the real vitamin....Vitamin D3).
Consider taking a higher dose during the Fall and Winter months.
Also consider taking a large vitamin K2. And there are
various forms of K2 the two that are available here in the
States over the counter are vitamin K2 MK-4 and MK-7.
If you live in Canada, Health Canada wants you to hurry
up and break a bone and die as the forbid vitamin K supplements.
For no good reasons other than the exercise of power.
Vitamin K helps to prevent ectopic
calcifications. Which is a bugaboo of the anti-vitamin crowd
when it comes to vitamin D use. Interestingly
high PTH levels caused by low vitamin D levels are
a risk factor for ectopic calcium deposits in the soft tissues.
Think milligrams not micrograms on the topic of vitamin K
supplementation.

Reply from: The Werewolf's Lair
Date: 23 Apr, 23:24
--
"Those who cannot learn from history are doomed to repeat it". -- George
Santayana
<trigonometry1972@gmail.com> wrote in message
news:ee1bb584-3f71-4af9-85e1-99dcd0cb9df7@p25g2000hsf.googlegroups.com...
> On Apr 23, 8:51 am, BoneLady <srsuppor...@gmail.com> wrote:
> Are you interested in an alternative to prescription drugs for
> osteoporosis? Strontium builds stronger bones than drugs like Fosamax,
> Actonel, or Boniva but without the dangerous side effects. For more
> information about strontium for treating osteoporosis, please visit
> Strontium For Bones athttp://strontiumforbones.blogspot.com/. My
> blog offers visitors discussions, information, and links which will be
> updated periodically

The blog took too long download when I wanted to comment for impatient
me.

You must be real impatient, as even with dial-up, this blog only takes a
minute to download so please come back and check it out and make your
comments.

The blog mentions also taking 1200 mg of calcium, 500 mg of Magnesium,
and a 1000 IU of D.

I'll suggest you use some other form than magnesium oxide as it
has quite poor absorbed out of the gut. Citrate or even sulfate
forms are better absorbed. Split the dose 3 or 4 ways to avoid
loose bowels.

Don't assume a 1000 IU of D is enough.

Clinical trials have shown that 1000 IU is a safe and effective amount for
Vitamin D. Taking too much D, as it is stored in the body, could result in
not only toxicity but loss of calicium from bone and calcium deposits in
arteries and organs.

If you are made of money have your late winter serum value checked as the
is likely your yearly nadir value for 25 OH vitamin D.
Choose vitamin D3 especially if you are taking large
loading dose. The body doesn't hang on to the so-called
vitamin D2 (really analog to what is the real vitamin....Vitamin D3).
Consider taking a higher dose during the Fall and Winter months.
Also consider taking a large vitamin K2. And there are
various forms of K2 the two that are available here in the
States over the counter are vitamin K2 MK-4 and MK-7.
If you live in Canada, Health Canada wants you to hurry
up and break a bone and die as the forbid vitamin K supplements.
For no good reasons other than the exercise of power.
Vitamin K helps to prevent ectopic
calcifications. Which is a bugaboo of the anti-vitamin crowd
when it comes to vitamin D use. Interestingly
high PTH levels caused by low vitamin D levels are
a risk factor for ectopic calcium deposits in the soft tissues.
Think milligrams not micrograms on the topic of vitamin K
supplementation.



Reply from: Kevysmom
Date: 23 Apr, 23:43
> "Those who cannot learn from history are doomed to repeat it". -- George
> Santayana


I hope not, I would hate another 4 more years of a republican
president.




On Apr 23, 5:24 pm, "The Werewolf's Lair" <werewolfk...@earthlink.net>
wrote:
> --
> "Those who cannot learn from history are doomed to repeat it". -- George
> Santayana<trigonometry1...@gmail.com> wrote in message
>
> news:ee1bb584-3f71-4af9-85e1-99dcd0cb9df7@p25g2000hsf.googlegroups.com...
>
> > On Apr 23, 8:51 am, BoneLady <srsuppor...@gmail.com> wrote:
> > Are you interested in an alternative to prescription drugs for
> > osteoporosis? Strontium builds stronger bones than drugs like Fosamax,
> > Actonel, or Boniva but without the dangerous side effects. For more
> > information about strontium for treating osteoporosis, please visit
> > Strontium For Bones athttp://strontiumforbones.blogspot.com/. My
> > blog offers visitors discussions, information, and links which will be
> > updated periodically
>
> The blog took too long download when I wanted to comment for impatient
> me.
>
> You must be real impatient, as even with dial-up, this blog only takes a
> minute to download so please come back and check it out and make your
> comments.
>
> The blog mentions also taking 1200 mg of calcium, 500 mg of Magnesium,
> and a 1000 IU of D.
>
> I'll suggest you use some other form than magnesium oxide as it
> has quite poor absorbed out of the gut. Citrate or even sulfate
> forms are better absorbed. Split the dose 3 or 4 ways to avoid
> loose bowels.
>
> Don't assume a 1000 IU of D is enough.
>
> Clinical trials have shown that 1000 IU is a safe and effective amount for=

> Vitamin D. Taking too much D, as it is stored in the body, could result in=

> not only toxicity but loss of calicium from bone and calcium deposits in
> arteries and organs.
>
> If you are made of money have your late winter serum value checked as the
> is likely your yearly nadir value for 25 OH vitamin D.
> Choose vitamin D3 especially if you are taking large
> loading dose. The body doesn't hang on to the so-called
> vitamin D2 (really analog to what is the real vitamin....Vitamin D3).
> Consider taking a higher dose during the Fall and Winter months.
> Also consider taking a large vitamin K2. And there are
> various forms of K2 the two that are available here in the
> States over the counter are vitamin K2 MK-4 and MK-7.
> If you live in Canada, Health Canada wants you to hurry
> up and break a bone and die as the forbid vitamin K supplements.
> For no good reasons other than the exercise of power.
> Vitamin K helps to prevent ectopic
> calcifications. Which is a bugaboo of the anti-vitamin crowd
> when it comes to vitamin D use. Interestingly
> high PTH levels caused by low vitamin D levels are
> a risk factor for ectopic calcium deposits in the soft tissues.
> Think milligrams not micrograms on the topic of vitamin K
> supplementation.


Reply from: BoneLady
Date: 24 Apr, 22:14
On Apr 23, 1:36 pm, "trigonometry1...@gmail.com |"
<trigonometry1...@gmail.com> wrote:
> > On Apr 23, 8:51 am, BoneLady <srsuppor...@gmail.com> wrote:
> > Are you interested in an alternative to prescription drugs for
> > osteoporosis? Strontium builds stronger bones than drugs like Fosamax,
> > Actonel, or Boniva but without the dangerous side effects. For more
> > information about strontium for treating osteoporosis, please visit
> > Strontium For Bones athttp://strontiumforbones.blogspot.com/.  My
> > blog offers visitors discussions, information, and links which will be
> > updated periodically
>
> The blog took too long download when I wanted to comment for impatient
> me.

Try being more patient. My blog has been tested on dial-up and only
takes less than a minute to load on 50Kps service.

> The blog mentions also taking 1200 mg of calcium, 500 mg of Magnesium,
> and a 1000 IU of D.
>
> I'll suggest you use some other form than magnesium oxide as it
> has quite poor absorbed out of the gut. Citrate or even sulfate
> forms are better absorbed. Split the dose 3 or 4 ways to avoid
> loose bowels.
>
> Don't assume a 1000 IU of D is enough. If you are made of
> money have your late winter serum value checked as the
> is likely your yearly nadir value for 25 OH vitamin D.
> Choose vitamin D3 especially if you are taking large
> loading dose. The body doesn't hang on to the so-called
> vitamin D2 (really analog to what is the real vitamin....Vitamin D3).
> Consider taking a higher dose during the Fall and Winter months.
> Also consider taking a large vitamin K2. And there are
> various forms of K2 the two that are available here in the
> States over the counter are vitamin K2 MK-4 and MK-7.
> If you live in Canada, Health Canada wants you to hurry
> up and break a bone and die as the forbid vitamin K supplements.
> For no good reasons other than the exercise of power.
> Vitamin K helps to prevent ectopic
> calcifications. Which is a bugaboo of the anti-vitamin crowd
> when it comes to vitamin D use. Interestingly
> high PTH levels caused by low vitamin D levels are
> a risk factor for ectopic calcium deposits in the soft tissues.
> Think milligrams not micrograms on the topic of vitamin K
> supplementation.


Reply from: Taka
Date: 25 Apr, 03:16
IMHO boron is better and safer than Strontium for bone and cartilage
health - do a search on it and see. Many parts of the World's soil
are depleted of boron. I haven't seen yet how it actually works on
molecular level but it looks like it has something to do with the
membranes and lipid metabolism.

Taka

Reply from: Marshall Price
Date: 04 May, 00:33
BoneLady wrote:
> On Apr 23, 1:36 pm, "trigonometry1...@gmail.com |"
> <trigonometry1...@gmail.com> wrote:
>>> On Apr 23, 8:51 am, BoneLady <srsuppor...@gmail.com> wrote:
>>> Are you interested in an alternative to prescription drugs for
>>> osteoporosis? Strontium builds stronger bones than drugs like Fosamax,
>>> Actonel, or Boniva but without the dangerous side effects. For more
>>> information about strontium for treating osteoporosis, please visit
>>> Strontium For Bones athttp://strontiumforbones.blogspot.com/. My
>>> blog offers visitors discussions, information, and links which will be
>>> updated periodically
>> The blog took too long download when I wanted to comment for impatient
>> me.
>
> Try being more patient. My blog has been tested on dial-up and only
> takes less than a minute to load on 50Kps service.

I found it surprising that strontium (atomic number 38, directly
below calcium in the periodic table) not only encourages osteoblasts and
discourages osteoclasts, but it also enters sufficiently into bone
mineralization to "confuse" the radiologists so they have to distinguish
between real bone "density" and the "density" caused by the greater
radio-opacity of strontium compared to calcium.

It makes me wonder how important strontium is in human nutrition, how
abundant it is, and whether it ought to be added to soils.

--
Marshall Price of Miami
Known to Yahoo as d021317c

Reply from: Larry
Date: 23 Apr, 22:58
BoneLady wrote:
> Are you interested in an alternative to prescription drugs for
> osteoporosis? Strontium builds stronger bones than drugs like Fosamax,
> Actonel, or Boniva but without the dangerous side effects. For more
> information about strontium for treating osteoporosis, please visit
> Strontium For Bones at http://strontiumforbones.blogspot.com/. My
> blog offers visitors discussions, information, and links which will be
> updated periodically.
Can I just ask ... since this is not a prescription that is dispensed by
a pharmacy and prescribed by a doctor, and has never been through any
kind of clinical trial, how would we really know whether there are side
effects or not?

Larry

Reply from: BoneLady
Date: 24 Apr, 17:30
On Apr 23, 4:58 pm, Larry <la...@nospam.net> wrote:
> BoneLady wrote:
> > Are you interested in an alternative to prescription drugs for
> > osteoporosis? athttp://strontiumforbones.blogspot.com/.  My
> > > Can I just ask ... since this is not a prescription that is dispensed =
by
> a pharmacy and prescribed by a doctor, and has never been through any
> kind of clinical trial, how would we really know whether there are side
> effects or not?
>
> Larry
Clinical studies utilizing different forms of strontium have been
conducted since the l950s.Regardless of the form, it is the elemental
strontium that is beneficial for bones.Visit my website for links to
some of the clinical trials.I have been taking strontium citrate for
three months with no side effects except mild constipation, which I
relieved by increasing my fiber intake. BoneLady athttp://strontiumforbones.=
blogspot.com/

Reply from: trigonometry1972@gmail.com |
Date: 24 Apr, 20:36
On Apr 24, 8:30 am, BoneLady <srsuppor...@gmail.com> wrote:
> On Apr 23, 4:58 pm, Larry <la...@nospam.net> wrote:> BoneLady wrote:
> > > Are you interested in an alternative to prescription drugs for
> > > osteoporosis?  athttp://strontiumforbones.blogspot.com/.  My
> > > > Can I just ask ... since this is not a prescription that is dispense=
d by
> > a pharmacy and prescribed by a doctor, and has never been through any
> > kind of clinical trial, how would we really know whether there are side
> > effects or not?
>
> > Larry
>
> Clinical studies utilizing different forms of strontium have been
> conducted since the l950s.Regardless of the form, it is the elemental
> strontium that is beneficial for bones.Visit my website for links to
> some of the clinical trials.I have been taking strontium citrate for
> three months with no side effects except mild constipation, which I
> relieved by increasing my fiber intake. BoneLady athttp://strontiumforbone=
s.blogspot.com/


The strontium ranelate related research funded by
those promoting it medical use is careful to
ignore the fact that it is the strontium is the active
ingredient and the ranelate is mirrorly the chelating
agent, IMO. To insist the ranelate chelate is the
only active form is the product of dishonest legalism not
hard edge science, IMO.

Here is a piece of cell culture work that suggest
what I just wrote.

0581 The Effects of Strontium Citrate on Osteoblast
Proliferation and Differentiation

A. BEUTTENMULLER, and R. DZIAK, SDM
College of Dental Sciences,
Buffalo, NY, USA

Recent research has shown that stable strontium
as well as some strontium salts increase bone
metabolism in osteoblasts obtained from rodent
calvaria cultures and that this element, particularly
in the form of strontium ranelate, may be useful
in the treatment of osteoporosis and other
diseases of bone remodeling.

Objectives: To assess the effects of strontium citrate,
a product commonly available as a nutritional supplement,
on the proliferation and differentiation of osteoblastic
cells obtained from human alveolar bone.

Methods: Primary osteoblasts, obtained with patients'
consent from human alveolar bone residues at the time
of third molar extractions and explanted in culture,
were seeded at a concentration of 105 cells/ml in
24 well polystyrene plates in BGJb media
containing 10% FCS. After the cells reached a
semiconfluent stage, strontium citrate
(bibasic anhydrous, pure grade from Jost Chemical)
at various concentrations (0.05-1.0 mM) was added.
The experiments performed included a MTT test
which assesses viability/proliferation with a
measure of mitochondrial activity and a
biochemical assay for alkaline phosphate
activity, an early maker of osteoblastic
cell differentiation. Measurements were
performed at 24, 48, and 72hrs.

Results: The data were analyzed using ANOVA.
The MTT test showed the cells to be responsive to
strontium citrate with significant increases
(p<0.05) in cellular activity/proliferation at
24 and 48 hrs. Alkaline phosphatase activity was
significantly enhanced (p<0.05) at 48 and 72 hrs
with strontium citrate concentrations in the
test range. Conclusion: The data support the
hypothesis that strontium citrate increases
the proliferative/alkaline phosphatase activity
of human osteoblastic cells from alveolar bone.
The results validate previous research that has
been done with other forms of strontium in
clinical studies and rodent calvarial cells and
indicates that strontium citrate could be a
promising agent in treating oral as well as
systemic bone disorders.

Funded by Dental Medicine Centennial Fund

___________________

By the way topical strontium is a more effective
agent against sensitive teeth than is fluoride.
I speak from personal experience.

Reply from: Larry
Date: 25 Apr, 02:33
A complete clinical trial result lists the side effects and the
percentage of patients affected by each ... along with the number of
patients tested. I don't see that here. Can you point me to that
information because that's what I was looking for. Thanks.

Larry

BoneLady wrote:
> On Apr 23, 4:58 pm, Larry <la...@nospam.net> wrote:
>
>>BoneLady wrote:
>>
>>>Are you interested in an alternative to prescription drugs for
>>>osteoporosis? athttp://strontiumforbones.blogspot.com/. My
>>>
>>>>Can I just ask ... since this is not a prescription that is dispensed by
>>
>>a pharmacy and prescribed by a doctor, and has never been through any
>>kind of clinical trial, how would we really know whether there are side
>>effects or not?
>>
>>Larry
>
> Clinical studies utilizing different forms of strontium have been
> conducted since the l950s.Regardless of the form, it is the elemental
> strontium that is beneficial for bones.Visit my website for links to
> some of the clinical trials.I have been taking strontium citrate for
> three months with no side effects except mild constipation, which I
> relieved by increasing my fiber intake. BoneLady athttp://strontiumforbones.blogspot.com/

Reply from: Bruce in Bangkok
Date: 25 Apr, 04:05
On Thu, 24 Apr 2008 20:33:27 -0400, Larry <larry@nospam.net> wrote:

>A complete clinical trial result lists the side effects and the
>percentage of patients affected by each ... along with the number of
>patients tested. I don't see that here. Can you point me to that
>information because that's what I was looking for. Thanks.
>
>Larry
>
>BoneLady wrote:
>> On Apr 23, 4:58 pm, Larry <la...@nospam.net> wrote:
>>
>>>BoneLady wrote:
>>>
>>>>Are you interested in an alternative to prescription drugs for
>>>>osteoporosis? athttp://strontiumforbones.blogspot.com/. My
>>>>
>>>>>Can I just ask ... since this is not a prescription that is dispensed by
>>>
>>>a pharmacy and prescribed by a doctor, and has never been through any
>>>kind of clinical trial, how would we really know whether there are side
>>>effects or not?
>>>
>>>Larry

The Strontium ranelate I take (a prescription medicine, by the way)
comes complete with the standard physician's information sheet listing
dosages, side effects, results of testing, and so on. It appears to
be a professionally produced product (Les Laboratoire Servier -
France).

Bruce-in-Bangkok
(correct email address for reply)

Reply from: trigonometry1972@gmail.com |
Date: 30 Apr, 09:15
On Apr 24, 7:05 pm, Bruce in Bangkok <b*paige*125@g*mail.com> wrote:
> On Thu, 24 Apr 2008 20:33:27 -0400, Larry <la...@nospam.net> wrote:
> >A complete clinical trial result lists the side effects and the
> >percentage of patients affected by each ... along with the number of
> >patients tested. I don't see that here. Can you point me to that
> >information because that's what I was looking for. Thanks.
>
> >Larry
>
> >BoneLady wrote:
> >> On Apr 23, 4:58 pm, Larry <la...@nospam.net> wrote:
>
> >>>BoneLady wrote:
>
> >>>>Are you interested in an alternative to prescription drugs for
> >>>>osteoporosis?  athttp://strontiumforbones.blogspot.com/.  My
>
> >>>>>Can I just ask ... since this is not a prescription that is dispensed=
by
>
> >>>a pharmacy and prescribed by a doctor, and has never been through any
> >>>kind of clinical trial, how would we really know whether there are side=

> >>>effects or not?
>
> >>>Larry
>
> The Strontium ranelate I take (a prescription medicine, by the way)
> comes complete with the standard physician's information sheet listing
> dosages, side effects, results of testing,  and so on. It appears to
> be a professionally produced product (Les Laboratoire Servier -
> France).
>
> Bruce-in-Bangkok
> (correct email address for reply)

No, I think you misunderstand Larry. He is casting his
doubts on strontium citrate not on strontium ranelate.
No matter as Bonelady points out whichever salt it is
contained in here is going to disassociate in the stomach
and intestines.

Trig

"The world has too few chemistry majors and too many lawyers.
There is too much bad common sense and too little good sense
and the latter is rarely common........Trig"

Reply from: BoneLady
Date: 24 Apr, 21:42
On Apr 23, 4:58 pm, Larry <la...@nospam.net> wrote:
> BoneLady wrote:
> > Are you interested in an alternative to prescription drugs for
> > osteoporosis? Strontium builds stronger bones than drugs like Fosamax,
> > Actonel, or Boniva but without the dangerous side effects. For more
> > information about strontium for treating osteoporosis, please visit
> > Strontium For Bones athttp://strontiumforbones.blogspot.com/.  My
> > blog offers visitors discussions, information, and links which will be
> > updated periodically.
>
> Can I just ask ... since this is not a prescription that is dispensed by
> a pharmacy and prescribed by a doctor, and has never been through any
> kind of clinical trial, how would we really know whether there are side
> effects or not?
>
> Larry

Strontium ranelate is a prescription drug used in Western Europe and
Asia and has been through several clinical trials conducted by
Servier, its manufacturer in France. These studies are all detailed on
my blog and show conclusively that strontium is as effective as
prescription drugs, may even produce stronger bones, and has few side
effects. Strontium citrate is available non-prescription in the US and
is just as effective as the ranelate form as all forms of strontium
ionize in the stomach and become protein-bound for absorption so it
doesn't matter what form you take, although I believe that the citrate
form is less toxic than the ranelate form.


Reply from: Ron Peterson
Date: 24 Apr, 00:12
On Apr 23, 10:51 am, BoneLady <srsuppor...@gmail.com> wrote:
> Are you interested in an alternative to prescription drugs for
> osteoporosis? Strontium builds stronger bones than drugs like Fosamax,
> Actonel, or Boniva but without the dangerous side effects. For more
> information about strontium for treating osteoporosis, please visit
> Strontium For Bones athttp://strontiumforbones.blogspot.com/.  My
> blog offers visitors discussions, information, and links which will be
> updated periodically.

I don't believe that strontium is considered a nutrient and that makes
it difficult to recommend.

And since strontium is more dense to xrays, it can cause misleading
BMD tests.

The tests have only been done with strontium renelate which makes it
hard to conclude that strontium citrate would have the same action.

--
Ron



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