Bloodletting Against Atherosclerosis

Bloodletting Against Atherosclerosis

Blood donation, body iron status and carotid intima-media thickness

Author(s): Engberink, M.F.; Geleijnse, J.M.; Durga, J.; Swinkels,
D.W.; Kort, W.L.A.M. de; Schouten, E.G.; Verhoef, P.
Source: Atherosclerosis 196 (2008)2. - ISSN 0021-9150 - p. 856 - 862.
Department(s): Afdeling Humane voeding (Division of Human Nutrition)
Research programme(s): Graduate School VLAG (2004 - 2010 )
Subtheme: =E2=90=96D. Nutrition, metabolism and health
Type of publication: Article in refereed journal
Year of publication: 2008
Abstract:
Iron could promote free radical formation, which may lead to injury of
the arterial wall and atherosclerosis.
Blood donation may reduce cardiovascular risk by lowering body iron
status.
We collected data on blood donation history and intima-media thickness
of the common carotid artery (CIMT) in 819 subjects (50-70 years), who
were recruited from municipal and blood bank registries in The
Netherlands.
Serum iron parameters were assessed, including non-transferrin bound
iron (NTBI) that has recently been found in conditions of iron
overload.
Serum ferritin was lower in current donors (n=3D443; 44mug/L) than in ex-
donors (n=3D120; 114mug/L) and never-donors (n=3D256; 124mug/L, P for
trend <0.001).
For NTBI, values were 2.33, 2.54, and 2.51mumol/L, respectively
(P<0.05). CIMT was slightly reduced in frequent donors (i.e., >/=3D49
times during life or >/=3D2 times per year), although not statistically
significant.
CIMT was not significantly related to NTBI.
Frequent blood donation, resulting in lowered body iron, might give
some protection against accelerated atherosclerosis.


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Re: Bloodletting Against Atherosclerosis

On Fri, 25 Apr 2008 8:35:11 -0500, ironjustice@aol,com wrote
(in message
<81f12d96-52cd-410c-af54-47141aa0b310@y18g2000pre.googlegroups,com >):

> Frequent blood donation, resulting in lowered body iron, might give
> some protection against accelerated atherosclerosis.

Is thst an iron-clad guarantee?

Re: Bloodletting Against Atherosclerosis


"J666" <j666@j666mail,com > wrote in message
news:0001HW.C437509900031A56F0407530@news-server.rgv.rr,com ...
> On Fri, 25 Apr 2008 8:35:11 -0500, ironjustice@aol,com wrote
> (in message
> <81f12d96-52cd-410c-af54-47141aa0b310@y18g2000pre.googlegroups,com >):
>
>> Frequent blood donation, resulting in lowered body iron, might give
>> some protection against accelerated atherosclerosis.
>
> Is thst an iron-clad guarantee?
>

No, it's a pinhole in a rubber guarantee.



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So it is an "ironiotic" IRONic guarantee

On Fri, 25 Apr 2008 12:37:55 -0500, Machete wrote
(in message <1209144611_8844@news.newsfeeds,com >):

>> Is thst an iron-clad guarantee?
>>
>
> No, it's a pinhole in a rubber guarantee.

So it is an "ironiotic" IRONic guarantee

Re: Bloodletting Against Atherosclerosis

On Apr 25, 1:37 pm, "Machete" <Mach...@home,com > wrote:
> "J666" <j...@j666mail,com > wrote in message
>
> news:0001HW.C437509900031A56F0407530@news-server.rgv.rr,com ...
>
> > On Fri, 25 Apr 2008 8:35:11 -0500, ironjust...@aol,com wrote
> > (in message
> > <81f12d96-52cd-410c-af54-47141aa0b...@y18g2000pre.googlegroups,com >):
>
> >> Frequent blood donation, resulting in lowered body iron, might give
> >> some protection against accelerated atherosclerosis.
>
> > Is thst an iron-clad guarantee?
>
> No, it's a pinhole in a rubber guarantee.

Like Pascal's Wager.