Re: Bone Marrow Treatments Restore NervesOn May 7, 9:56 am, ironjustice <ironjust...@cashette,com > wrote:"Oral
chelation improved many symptoms." <<
Just wanted to point out that they think it was caused by giving the
chick .. iron.
"Coincident with aggressive oral iron replacement"
"Ataxia, lower extremity spasticity , chorea ,neurological
dysfunction, cognitive decline"
"Oral chelating agents have not been used in neurological diseases of
iron metabolism."
"Oral chelation improved many symptoms."
Who loves ya.
Tom
Jesus Was A Vegetarian!
http :// tinyurl,com /2r2nkh
Man Is A Herbivore!
http :// tinyurl,com /a3cc3
DEAD PEOPLE WALKING
http :// tinyurl,com /zk9fk
> On May 7, 9:14 am, ironjustice <ironjust...@cashette,com > wrote: the
> same treatment being replaced ? <<
>
> "Ataxia, lower extremity spasticity , chorea ,neurological
> dysfunction, cognitive decline"
>
> "Oral chelating agents have not been used in neurological diseases of
> iron metabolism."
>
> "Oral chelation improved many symptoms."
>
> J Neurol Neurosurg Psychiatry. 2008 Apr;79(4):467-70. Epub 2007 Oct
> 2. Links
> Aceruloplasminaemia with progressive atrophy without brain iron
> overload: treatment with oral chelation.
> Skidmore FM, Drago V, Foster P, Schmalfuss IM, Heilman KM, Streiff
> RR.
> University of Florida School of Medicine, North Florida/South Georgia
> VA Medical Center, McKnight Brain Institute at UF, 100 S. Newell
> Drive, Room L3-100, PO Box 100236, Gainesville, FL 32610-0236, USA.
> frank.skidm...@neurology.ufl.edu
>
> BACKGROUND:
> Hereditary aceruloplasminaemia is a disorder of iron metabolism that
> is characterised by iron accumulation in the brain and other visceral
> organs. In previously reported cases, individuals with the disorder
> were noted to have evidence of iron accumulation in the brain. Oral
> chelating agents have not been used in neurological diseases of iron
> metabolism.
> METHODS:
> A 54-year-old woman who presented with ataxia, lower extremity
> spasticity and chorea was evaluated for evidence of the source of
> neurological dysfunction. RESULTS: Blood studies revealed no
> detectable ceruloplasmin. Marked iron overload was defined by a liver
> biopsy, which showed a variegated pattern consistent with a primary
> cause of iron overload. Review of MRI scans showed progressive brain
> atrophy without visible iron accumulation occurring over a 5-year
> period. The history suggested that neurodegeneration was coincident
> with aggressive oral iron replacement. Oral chelation improved many
> symptoms.
> CONCLUSIONS:
> Our findings in this patient suggest that disorders of iron transport
> such as aceruloplasminaemia can be a cause of neurological symptoms
> such as chorea and cognitive decline, as well as progressive
> neurodegeneration in the absence of visible iron on MRI scans. We
> found that oral iron chelation was effective at improving symptoms.
>
> PMID: 17911185
>
> Who loves ya.
> Tom
>
> Jesus Was A Vegetarian! http :// tinyurl,com /2r2nkh
>
> Man Is A Herbivore! http :// tinyurl,com /a3cc3
>
> DEAD PEOPLE WALKING http :// tinyurl,com /zk9fk
>
>
>
> > On May 7, 9:02 am, ironjustice <ironjust...@cashette,com > wrote: Is
> > it coincidence aplasia is linked to erythrocytosis / increased red
> > blood cell production and so is MS .. IE: polycythemia / viscosity of
> > the blood ? <<
>
> > Acta Haematol. 1994;92(3):136-9.Links
> > Coincidence of severe aplastic anaemia with multiple sclerosis or
> > thyroid disorders. Report of 5 cases.
> > Hinterberger-Fischer M, Kier P, Forstinger I, Lechner K, Kornek G,
> > Breyer S, Ogris H, Pont J, Hinterberger W.
> > Division of Hematology and Blood Coagulation, University of Vienna,
> > Austria.
>
> > Five patients with severe aplastic anaemia (SAA) who, simultaneously
> > (n = 3) or consecutively (n = 2), presented with multiple sclerosis
> > (MS) (n = 2) or immune hyperthyroidism (IHT) (n = 2) or subacute
> > thyroiditis (n = 1) are described. Two female patients with MS
> > developed SAA after a small dose of azathioprine. Another patient
> > simultaneously presented with IHT and SAA. SAA and MS responded to
> > cyclosporine while IHT required 131I. Relapsing SAA in 1 patient with
> > MS was treated with antithymocyte globulin (ATG) which induced acute
> > exacerbation of MS. Despite the low total dose of ATG (31.5 mg/kg),
> > complete remission of SAA was obtained. Two other patients developed
> > thyroid disorders, 42 and 106 months after successful
> > immunosuppression with ATG/high-dose methylprednisolone. IHT and
> > subacute thyroiditis were successfully treated with 131I or
> > prednisolone, respectively, without recurrence of SAA in both cases.
> > These are the first documented cases of SAA evolving in the course of
> > MS while the coincidence with IHT was already described. Since
> > enhanced expression of interferon-gamma plays a crucial role in SAA as
> > well as in MS and in IHT, similar pathogenetic principles may apply
> > for these seemingly unrelated disorders.
>
> > PMID: 7871951 [PubMed - indexed for MEDLINE]
>
> > Who loves ya.
> > Tom
>
> > Jesus Was A Vegetarian! http :// tinyurl,com /2r2nkh
>
> > Man Is A Herbivore! http :// tinyurl,com /a3cc3
>
> > DEAD PEOPLE WALKING http :// tinyurl,com /zk9fk
>
> > > On May 7, 7:42 am, ironjustice <teamtan...@hotmail,com > wrote:Isn't
> > > this the same treatment being replaced by bloodletting in
> > > Sickle , Thalassemia and Leukemia .. ? <<
>
> > > Sure sounds like the same treatment being replaced by iron reduction?
>
> > > "bone marrow stem-cell transplants"
>
> > > "pluripotent stem cells in the bone marrow"
>
> > > Is it coincidence aplasia is linked to erythrocytosis / increased red
> > > blood cell production and so is MS .. IE: polycythemia / viscosity of
> > > the blood ?
>
> > > "Complete recovery after iron chelation in aplastic anemia"
>
> > > They treated this kid for five years .. aggressively .. and when and
> > > ONLY when the kid was failing DUE TO their interventions / iron
> > > buildup .. did they finally cure the kid.
>
> > > Removed the iron **totally** ..
> > > IE: targeted the iron .. and the kid was cured.
> > > ---------
>
> > > Complete hematopoietic recovery after continuous iron chelation
> > > therapy in a patient with severe aplastic anemia with secondary
> > > hemochromatosis.
> > > Park SJ, Han CW
>
> > > J Korean Med Sci 2008 Apr; 23(2):320-3.
>
> > > A 16-yr-old male patient with hemochromatosis due to multiple packed
> > > red blood cell transfusions was referred to our emergency center for
> > > the treatment of severe aplastic anemia and dyspnea. He was diagnosed
> > > with aplastic anemia at 11-yr of age.
> > > He had received continuous transfusions because an HLA-matched marrow
> > > donor was unavailable.
> > > Following a continuous, approximately 5-yr transfusion, he was noted
> > > to develop hemochromatosis.
> > > He had a dilated cardiomyopathy and required diuretics and digitalis,
> > > multiple endocrine and liver dysfunction, generalized bleeding, and
> > > skin pigmentation.
> > > A total volume of red blood cell transfusion before deferoxamine
> > > therapy was about 96,000 mL.
> > > He received a regular iron chelation therapy (continuous intravenous
> > > infusion of deferoxamine, 50 mg/kg/day for 5
> > > days q 3-4 weeks) for approximately seven years after the onset of
> > > multiple organ failures.
> > > His cytopenia and organ dysfunctions began to
> > > be gradually recovered since about 2002, following a 4-yr
> > > deferoxamine treatment.
> > > He showed completely normal ranges of peripheral blood cell
> > > counts, heart size, and liver function two years ago.
> > > He has not
> > > received any transfusions for the last four years.
> > > This finding suggests that a continuous deferoxamine infusion may
> > > play
> > > a role in the immune regulation in addition to iron chelation effect.
> > > Journal of Korean medical science
> > > [J Korean Med Sci]
> > > --------------------------------------------------------------------------------
>
> > > http :// en.wikipedia.org/wiki/Aplastic anemia
>
> > > Treating aplastic anemia involves suppression of the immune system,
> > > an effect achieved by daily medicine intake, or, in more severe
> > > cases,
> > > a bone marrow transplant, a potential cure but a risky procedure.[1]
> > > The transplanted bone marrow replaces the failing bone marrow cells
> > > with new ones from a matching donor.
> > > The pluripotent stem cells in the bone marrow reconstitute all three
> > > blood cell lines, giving the patient a new immune system, red blood
> > > cells, and platelets.
> > > However, besides the risk of graft failure, there is also a risk that
> > > the newly created white blood cells may attack the rest of the body
> > > ("graft-versus-host disease").
>
> > > Medical therapy of aplastic anemia often includes a short course of
> > > anti-thymocyte globulin (ATG) or anti-lymphocyte globulin (ALG) and
> > > several months of treatment with cyclosporin to modulate the immune
> > > system.
> > > Mild chemotherapy with agents such as cyclophosphamide and
> > > vincristine may also be effective.
> > > Antibodies therapy, such as ATG, targets T-cells, which are believed
> > > to attack the bone marrow.
> > > Steroids are generally ineffective.
>
> > > In the past, before the above treatments became available, patients
> > > with low leukocyte counts were often confined to a sterile room or
> > > bubble (to reduce risk of infections), as in the famed case of Ted
> > > DeVita.[2]
>
> > > Who loves ya.
> > > Tom
>
> > > Jesus Was A Vegetarian! http :// tinyurl,com /2r2nkh
>
> > > Man Is A Herbivore! http :// tinyurl,com /a3cc3
>
> > > DEAD PEOPLE WALKING http :// tinyurl,com /zk9fk
>
> > > > Isn't this the same treatment being replaced by bloodletting in
> > > > Sickle , Thalassemia and Leukemia .. ?
> > > > -----------------------------------
> > > > Bone Marrow Treatments Restore Nerves
> > > > 5/7/2008
>
> > > > BETHESDA, Maryland (Reuters) - An experiment that went wrong may
> > > > provide a new way to treat multiple sclerosis, a Canadian researcher
> > > > said on Tuesday. Patients who got bone marrow stem-cell transplants --
> > > > similar to those given to leukemia patients -- have enjoyed a
> > > > mysterious remission of their disease.
>
> > > > Who loves ya.
> > > > Tom
>
> > > > Jesus Was A Vegetarian! http :// tinyurl,com /2r2nkh
>
> > > > Man Is A Herbivore! http :// tinyurl,com /a3cc3
>
> > > > DEAD PEOPLE WALKING http :// tinyurl,com /zk9fk-Hidequoted text -
>
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