Add group to favorites
Back to post list
Send new message to group Search:
Post Subject:
85% Low On Iron
85% Low On Iron
This sounds "reasonable" .. TO a reasonable ..person .. does it .. ?
Does it .. ?
Iron added to all their foods .. eating meat which I might add is
HIGHLY more absorbed iron than plants in a
MIDDLECLASSFRICKENNEIGHBOURHOOD .. ?
"The proportion of girls with an iron intake below the Nordic
nutrition recommendations was 85%"
Iron status in Swedish teenage girls: impact of low dietary iron
bioavailability.
Hoppe M, Sjöberg A, Hallberg L, Hulthén L
Nutrition 2008 May 8.
OBJECTIVE: Although it is well known that bioavailability of iron in
the diet is important, it has not been fully elucidated in practice.
We investigated iron intake and iron absorption in the ordinary diet
of free-living individuals in relation to iron status and assessed
iron requirements.
METHODS: From a total of 1245 adolescent boys and girls included in
the Göteborg Adolescence Study of food habits, 28 adolescent girls
registered their food intake during 7 d. Iron intake was assessed on
the basis of these 7-d dietary records. Iron absorption was calculated
using an algorithm including enhancing and inhibiting dietary factors
on iron absorption in relation to individual iron status.
RESULTS: Available iron intake was 11.5 +/- 2.8 mg/d (mean +/- SD).
The proportion of girls with an iron intake below the Nordic nutrition
recommendations was 85% (n = 24). Calculated iron absorption was 1.09
+/- 0.59 mg/d (mean +/- SD). Only four girls satisfied their estimated
individual iron requirement concerning the absorbed amount of iron.
Iron depletion (serum ferritin concentration </=15 mug/L) was present
in 10 girls (36%), 2 of whom were also anemic (hemoglobin
concentration </=120 g/L).
CONCLUSION: Swedish adolescent girls seemed to have difficulties
satisfying their iron requirement in terms of absorbed amount. The
data support the view that iron intake and bioavailability of dietary
iron is important when evaluating whether iron requirements have been
met.
----------------------------------------------------------------------------=
----
More from this journal
Nutrition (Burbank, Los Angeles County, Calif.) [Nutrition]
Who loves ya.
Tom
Jesus Was A Vegetarian!
* tinyurl . com /2r2nkh
Man Is A Herbivore!
* tinyurl . com /a3cc3
DEAD PEOPLE WALKING
* tinyurl . com /zk9fk
This sounds "reasonable" .. TO a reasonable ..person .. does it .. ?
Does it .. ?
Iron added to all their foods .. eating meat which I might add is
HIGHLY more absorbed iron than plants in a
MIDDLECLASSFRICKENNEIGHBOURHOOD .. ?
"The proportion of girls with an iron intake below the Nordic
nutrition recommendations was 85%"
Iron status in Swedish teenage girls: impact of low dietary iron
bioavailability.
Hoppe M, Sjöberg A, Hallberg L, Hulthén L
Nutrition 2008 May 8.
OBJECTIVE: Although it is well known that bioavailability of iron in
the diet is important, it has not been fully elucidated in practice.
We investigated iron intake and iron absorption in the ordinary diet
of free-living individuals in relation to iron status and assessed
iron requirements.
METHODS: From a total of 1245 adolescent boys and girls included in
the Göteborg Adolescence Study of food habits, 28 adolescent girls
registered their food intake during 7 d. Iron intake was assessed on
the basis of these 7-d dietary records. Iron absorption was calculated
using an algorithm including enhancing and inhibiting dietary factors
on iron absorption in relation to individual iron status.
RESULTS: Available iron intake was 11.5 +/- 2.8 mg/d (mean +/- SD).
The proportion of girls with an iron intake below the Nordic nutrition
recommendations was 85% (n = 24). Calculated iron absorption was 1.09
+/- 0.59 mg/d (mean +/- SD). Only four girls satisfied their estimated
individual iron requirement concerning the absorbed amount of iron.
Iron depletion (serum ferritin concentration </=15 mug/L) was present
in 10 girls (36%), 2 of whom were also anemic (hemoglobin
concentration </=120 g/L).
CONCLUSION: Swedish adolescent girls seemed to have difficulties
satisfying their iron requirement in terms of absorbed amount. The
data support the view that iron intake and bioavailability of dietary
iron is important when evaluating whether iron requirements have been
met.
----------------------------------------------------------------------------=
----
More from this journal
Nutrition (Burbank, Los Angeles County, Calif.) [Nutrition]
Who loves ya.
Tom
Jesus Was A Vegetarian!
* tinyurl . com /2r2nkh
Man Is A Herbivore!
* tinyurl . com /a3cc3
DEAD PEOPLE WALKING
* tinyurl . com /zk9fk
Re: 85% Low On Iron
On May 13, 6:37=A0am, ironjustice <teamtan...@hotmail . com > wrote:"The
proportion of girls with an iron intake below the Nordic
nutrition recommendations was 85%"<<
"We were quite surprised by our findings"
Neurodevelopmental Delays Associated With Iron-Fortified Formula for
Healthy Infants CME
News Author: Martha Kerr, BSN
CME Author: D=E9sir=E9e Lie, MD, MSEd
Disclosures
Release Date: May 12, 2008; Valid for credit through May 12, 2009
Credits Available
Physicians - maximum of 0.25 AMA PRA Category 1 Credit(s)=99 for
physicians;
Family Physicians - up to 0.25 AAFP Prescribed credit(s) for
physicians
To participate in this internet activity: (1) review the target
audience, learning objectives, and author disclosures; (2) study the
education content; (3) take the post-test and/or complete the
evaluation; (4) view/print certificate View details.
Learning Objectives
Upon completion of this activity, participants will be able to:
Inform clinicians of the latest medical information on the effect of
iron fortification of formula on infant neurobehavioral outcomes as
presented at the PAS 2008, the Pediatric Academic Societies and Asian
Society for Pediatric Research Joint Meeting.
Describe the relevance of the findings on the effect of high vs low
iron fortification in infant formula on infant motor skills, memory,
visuospatial integration, reading, and IQ scores at 10 years to
clinicians in the care of their infant patient with normal or high
baseline hemoglobin.
Authors and Disclosures
Martha Kerr
Disclosure: Martha Kerr has disclosed no relevant financial
relationships.
D=E9sir=E9e Lie, MD, MSEd
Disclosure: D=E9sir=E9e Lie, MD, MSEd, has disclosed no relevant financial
relationships.
Brande Nicole Martin
Disclosure: Brande Nicole Martin has disclosed no relevant financial
information.
=46rom PAS 2008: Pediatric Academic Societies and Asian Society for
Pediatric Research Joint Meeting
May 12, 2008 (Honolulu) =97 Healthy, well-nourished children fed iron-
fortified formula as infants scored an average of 11 points lower on
IQ tests at 10 years of age than similar children fed low-iron
formula, investigators announced here at PAS 2008, the Pediatric
Academic Societies and Asian Society for Pediatric Research Joint
Meeting.
Ten-year follow-up data were examined for 494 healthy Chilean infants
who were not iron-deficient at baseline at 6 months of age and who
were randomly assigned to receive either iron-fortified formula,
containing 12 mg/L ferrous sulfate, or low-iron formula, containing
2.3 mg/L ferrous sulfate, for a year, with the objective of preventing
iron deficiency.
Principal investigator Betsy Lozoff, MD, professor of pediatrics and
communicable diseases at the University of Michigan, Ann Arbor,
reported that at 10-year follow-up, there were no background
differences between the 2 groups, but there were marked differences in
neurobehavioral growth and development.
Hemoglobin levels were assessed at every office visit from 6 months
through 10 years. Motor development on the Bruininks-Oseretsky test,
IQ scores, spatial memory, reading and arithmetic skills, and visual-
motor integration were assessed to measure the effect of iron-
fortified feedings on neurobehavioral growth and development, "when
iron levels were normal to begin with."
The low-iron group had higher scores "on every outcome" at 10 years,
Dr. Lozoff announced. The findings were significant for spatial memory
and visual motor integration (P < .05) and suggestive for IQ, visual
perception, and motor coordination (P < .10) compared with patients in
the iron-fortified group, who scored lower on all of these measures.
"Children who entered the trial with high hemoglobin levels,
suggesting iron sufficiency, showed poorer outcome if they received
iron-fortified formula.... There was an 11-point difference in IQ
scores [between the low-iron and high-iron groups]," Dr. Lozoff told
Medscape Pediatrics. "This was a significant difference."
"The randomized trial design suggests a causal relation between the 12
mg/L iron-fortified formula and poorer developmental outcome at 10
years," she noted. "The results raise the possibility that long-term
development is adversely affected in iron-sufficient infants who
receive formula fortified with iron at the level commonly used in the
United States."
Dr. Lozoff emphasized that the findings were for infants with adequate
nutrition at baseline. For poor infants, who may receive primarily
cow's milk, "a notoriously poor source of iron...the outcomes may be
different and likely favor iron-fortified formula," she stressed.
"I think it is important to understand the definition of 'low-iron'
and 'iron-fortified' formulas. These are FDA definitions," cautioned
Michael K. Georgieff, MD, professor of pediatrics and child
development and director of the Center for Neurobehavioral Development
at the University of Minnesota School of Medicine, Minneapolis, in an
interview with Medscape Pediatrics after Dr. Lozoff's presentation.
"Any formula with a content less than 6.7 mg/L of iron is considered
'low iron.' Originally, many of the unfortified formulas had as little
as 1.5 mg iron/L, and this caused extremely high rates of iron-
deficiency anemia and its attendant cognitive sequelae. In...the
1960s...an all-time low for breastfeeding rates, infants were fed
predominantly formula and were converted to whole milk at 6 months,
which put them into an even more negative iron balance," Dr. Georgieff
commented.
"When the formula industry started to make iron-fortified formula,
they added enough to not only keep the infant sufficient from 0 to 6
months (which can be achieved with 4 - 7 mg/L) but enough to 'tide the
child over' to 12 months, until they were eating more of a meat-based
diet rich in iron. When [Dr. Lozoff] did her study in Chile in the
early 1990s, these 2 types of formulas were still prevalent down
there," he continued.
"Given that the [American Academy of Pediatrics] and other
organizations now advocate breast-feeding for 12 months, and using
formula instead of whole milk after 6 months for those that are not
breast-feeding, the supplementation strategy of the 1960s seems
archaic," Dr. Georgieff said.
"[Dr. Lozoff's] study...is striking because it has a lot of children
in it. Moreover, the important finding is that the highly supplemented
formula was associated with poorer outcome only in the children who
were the most iron-sufficient to start with. Those with more normal
iron status had no adverse effect and those with low iron status
benefited from the high-iron formula.
"Most of us in the iron field would be comfortable with formulas
having less iron in them, more in the range of 4 to 7 mg/L, and that
there may be potential toxicity in certain groups consuming a high-
iron formula," Dr. Georgieff said.
"We were quite surprised by our findings," Dr. Lozoff noted. "I have
worked all of my life on the opposite hypothesis =97 that iron
supplementation leads to better infant health. Iron supplementation is
a concern on a global scale, but not in our country," she said.
Dr. Lozoff and Dr. Georgieff have disclosed no relevant financial
relationships.
PAS 2008: Pediatric Academic Societies and Asian Society for Pediatric
Research Joint Meeting: Poster 5340.2. Presented May 8, 2008.
Who loves ya.
Tom
Jesus Was A Vegetarian!
* tinyurl . com /2r2nkh
Man Is A Herbivore!
* tinyurl . com /a3cc3
DEAD PEOPLE WALKING
* tinyurl . com /zk9fk
> This sounds "reasonable" .. TO a reasonable ..person .. does it .. ?
>
> Does it .. ?
>
> Iron added to all their foods .. eating meat which I might add is
> HIGHLY more absorbed iron than plants in a
> MIDDLECLASSFRICKENNEIGHBOURHOOD .. ?
>
> "The proportion of girls with an iron intake below the Nordic
> nutrition recommendations was 85%"
>
> Iron status in Swedish teenage girls: impact of low dietary iron
> bioavailability.
> Hoppe M, Sj=F6berg A, Hallberg L, Hulth=E9n L
> Nutrition 2008 May 8.
>
> OBJECTIVE: Although it is well known that bioavailability of iron in
> the diet is important, it has not been fully elucidated in practice.
> We investigated iron intake and iron absorption in the ordinary diet
> of free-living individuals in relation to iron status and assessed
> iron requirements.
> METHODS: From a total of 1245 adolescent boys and girls included in
> the G=F6teborg Adolescence Study of food habits, 28 adolescent girls
> registered their food intake during 7 d. Iron intake was assessed on
> the basis of these 7-d dietary records. Iron absorption was calculated
> using an algorithm including enhancing and inhibiting dietary factors
> on iron absorption in relation to individual iron status.
> RESULTS: Available iron intake was 11.5 +/- 2.8 mg/d (mean +/- SD).
> The proportion of girls with an iron intake below the Nordic nutrition
> recommendations was 85% (n =3D 24). Calculated iron absorption was 1.09
> +/- 0.59 mg/d (mean +/- SD). Only four girls satisfied their estimated
> individual iron requirement concerning the absorbed amount of iron.
> Iron depletion (serum ferritin concentration </=3D15 mug/L) was present
> in 10 girls (36%), 2 of whom were also anemic (hemoglobin
> concentration </=3D120 g/L).
> CONCLUSION: Swedish adolescent girls seemed to have difficulties
> satisfying their iron requirement in terms of absorbed amount. The
> data support the view that iron intake and bioavailability of dietary
> iron is important when evaluating whether iron requirements have been
> met.
>
> --------------------------------------------------------------------------=
-=AD-----
> More from this journal
> Nutrition (Burbank, Los Angeles County, Calif.) [Nutrition]
>
> Who loves ya.
> Tom
>
> Jesus Was A Vegetarian! * tinyurl . com /2r2nkh
>
> Man Is A Herbivore! * tinyurl . com /a3cc3
>
> DEAD PEOPLE WALKING * tinyurl . com /zk9fk
On May 13, 6:37=A0am, ironjustice <teamtan...@hotmail . com > wrote:"The
proportion of girls with an iron intake below the Nordic
nutrition recommendations was 85%"<<
"We were quite surprised by our findings"
Neurodevelopmental Delays Associated With Iron-Fortified Formula for
Healthy Infants CME
News Author: Martha Kerr, BSN
CME Author: D=E9sir=E9e Lie, MD, MSEd
Disclosures
Release Date: May 12, 2008; Valid for credit through May 12, 2009
Credits Available
Physicians - maximum of 0.25 AMA PRA Category 1 Credit(s)=99 for
physicians;
Family Physicians - up to 0.25 AAFP Prescribed credit(s) for
physicians
To participate in this internet activity: (1) review the target
audience, learning objectives, and author disclosures; (2) study the
education content; (3) take the post-test and/or complete the
evaluation; (4) view/print certificate View details.
Learning Objectives
Upon completion of this activity, participants will be able to:
Inform clinicians of the latest medical information on the effect of
iron fortification of formula on infant neurobehavioral outcomes as
presented at the PAS 2008, the Pediatric Academic Societies and Asian
Society for Pediatric Research Joint Meeting.
Describe the relevance of the findings on the effect of high vs low
iron fortification in infant formula on infant motor skills, memory,
visuospatial integration, reading, and IQ scores at 10 years to
clinicians in the care of their infant patient with normal or high
baseline hemoglobin.
Authors and Disclosures
Martha Kerr
Disclosure: Martha Kerr has disclosed no relevant financial
relationships.
D=E9sir=E9e Lie, MD, MSEd
Disclosure: D=E9sir=E9e Lie, MD, MSEd, has disclosed no relevant financial
relationships.
Brande Nicole Martin
Disclosure: Brande Nicole Martin has disclosed no relevant financial
information.
=46rom PAS 2008: Pediatric Academic Societies and Asian Society for
Pediatric Research Joint Meeting
May 12, 2008 (Honolulu) =97 Healthy, well-nourished children fed iron-
fortified formula as infants scored an average of 11 points lower on
IQ tests at 10 years of age than similar children fed low-iron
formula, investigators announced here at PAS 2008, the Pediatric
Academic Societies and Asian Society for Pediatric Research Joint
Meeting.
Ten-year follow-up data were examined for 494 healthy Chilean infants
who were not iron-deficient at baseline at 6 months of age and who
were randomly assigned to receive either iron-fortified formula,
containing 12 mg/L ferrous sulfate, or low-iron formula, containing
2.3 mg/L ferrous sulfate, for a year, with the objective of preventing
iron deficiency.
Principal investigator Betsy Lozoff, MD, professor of pediatrics and
communicable diseases at the University of Michigan, Ann Arbor,
reported that at 10-year follow-up, there were no background
differences between the 2 groups, but there were marked differences in
neurobehavioral growth and development.
Hemoglobin levels were assessed at every office visit from 6 months
through 10 years. Motor development on the Bruininks-Oseretsky test,
IQ scores, spatial memory, reading and arithmetic skills, and visual-
motor integration were assessed to measure the effect of iron-
fortified feedings on neurobehavioral growth and development, "when
iron levels were normal to begin with."
The low-iron group had higher scores "on every outcome" at 10 years,
Dr. Lozoff announced. The findings were significant for spatial memory
and visual motor integration (P < .05) and suggestive for IQ, visual
perception, and motor coordination (P < .10) compared with patients in
the iron-fortified group, who scored lower on all of these measures.
"Children who entered the trial with high hemoglobin levels,
suggesting iron sufficiency, showed poorer outcome if they received
iron-fortified formula.... There was an 11-point difference in IQ
scores [between the low-iron and high-iron groups]," Dr. Lozoff told
Medscape Pediatrics. "This was a significant difference."
"The randomized trial design suggests a causal relation between the 12
mg/L iron-fortified formula and poorer developmental outcome at 10
years," she noted. "The results raise the possibility that long-term
development is adversely affected in iron-sufficient infants who
receive formula fortified with iron at the level commonly used in the
United States."
Dr. Lozoff emphasized that the findings were for infants with adequate
nutrition at baseline. For poor infants, who may receive primarily
cow's milk, "a notoriously poor source of iron...the outcomes may be
different and likely favor iron-fortified formula," she stressed.
"I think it is important to understand the definition of 'low-iron'
and 'iron-fortified' formulas. These are FDA definitions," cautioned
Michael K. Georgieff, MD, professor of pediatrics and child
development and director of the Center for Neurobehavioral Development
at the University of Minnesota School of Medicine, Minneapolis, in an
interview with Medscape Pediatrics after Dr. Lozoff's presentation.
"Any formula with a content less than 6.7 mg/L of iron is considered
'low iron.' Originally, many of the unfortified formulas had as little
as 1.5 mg iron/L, and this caused extremely high rates of iron-
deficiency anemia and its attendant cognitive sequelae. In...the
1960s...an all-time low for breastfeeding rates, infants were fed
predominantly formula and were converted to whole milk at 6 months,
which put them into an even more negative iron balance," Dr. Georgieff
commented.
"When the formula industry started to make iron-fortified formula,
they added enough to not only keep the infant sufficient from 0 to 6
months (which can be achieved with 4 - 7 mg/L) but enough to 'tide the
child over' to 12 months, until they were eating more of a meat-based
diet rich in iron. When [Dr. Lozoff] did her study in Chile in the
early 1990s, these 2 types of formulas were still prevalent down
there," he continued.
"Given that the [American Academy of Pediatrics] and other
organizations now advocate breast-feeding for 12 months, and using
formula instead of whole milk after 6 months for those that are not
breast-feeding, the supplementation strategy of the 1960s seems
archaic," Dr. Georgieff said.
"[Dr. Lozoff's] study...is striking because it has a lot of children
in it. Moreover, the important finding is that the highly supplemented
formula was associated with poorer outcome only in the children who
were the most iron-sufficient to start with. Those with more normal
iron status had no adverse effect and those with low iron status
benefited from the high-iron formula.
"Most of us in the iron field would be comfortable with formulas
having less iron in them, more in the range of 4 to 7 mg/L, and that
there may be potential toxicity in certain groups consuming a high-
iron formula," Dr. Georgieff said.
"We were quite surprised by our findings," Dr. Lozoff noted. "I have
worked all of my life on the opposite hypothesis =97 that iron
supplementation leads to better infant health. Iron supplementation is
a concern on a global scale, but not in our country," she said.
Dr. Lozoff and Dr. Georgieff have disclosed no relevant financial
relationships.
PAS 2008: Pediatric Academic Societies and Asian Society for Pediatric
Research Joint Meeting: Poster 5340.2. Presented May 8, 2008.
Who loves ya.
Tom
Jesus Was A Vegetarian!
* tinyurl . com /2r2nkh
Man Is A Herbivore!
* tinyurl . com /a3cc3
DEAD PEOPLE WALKING
* tinyurl . com /zk9fk
> This sounds "reasonable" .. TO a reasonable ..person .. does it .. ?
>
> Does it .. ?
>
> Iron added to all their foods .. eating meat which I might add is
> HIGHLY more absorbed iron than plants in a
> MIDDLECLASSFRICKENNEIGHBOURHOOD .. ?
>
> "The proportion of girls with an iron intake below the Nordic
> nutrition recommendations was 85%"
>
> Iron status in Swedish teenage girls: impact of low dietary iron
> bioavailability.
> Hoppe M, Sj=F6berg A, Hallberg L, Hulth=E9n L
> Nutrition 2008 May 8.
>
> OBJECTIVE: Although it is well known that bioavailability of iron in
> the diet is important, it has not been fully elucidated in practice.
> We investigated iron intake and iron absorption in the ordinary diet
> of free-living individuals in relation to iron status and assessed
> iron requirements.
> METHODS: From a total of 1245 adolescent boys and girls included in
> the G=F6teborg Adolescence Study of food habits, 28 adolescent girls
> registered their food intake during 7 d. Iron intake was assessed on
> the basis of these 7-d dietary records. Iron absorption was calculated
> using an algorithm including enhancing and inhibiting dietary factors
> on iron absorption in relation to individual iron status.
> RESULTS: Available iron intake was 11.5 +/- 2.8 mg/d (mean +/- SD).
> The proportion of girls with an iron intake below the Nordic nutrition
> recommendations was 85% (n =3D 24). Calculated iron absorption was 1.09
> +/- 0.59 mg/d (mean +/- SD). Only four girls satisfied their estimated
> individual iron requirement concerning the absorbed amount of iron.
> Iron depletion (serum ferritin concentration </=3D15 mug/L) was present
> in 10 girls (36%), 2 of whom were also anemic (hemoglobin
> concentration </=3D120 g/L).
> CONCLUSION: Swedish adolescent girls seemed to have difficulties
> satisfying their iron requirement in terms of absorbed amount. The
> data support the view that iron intake and bioavailability of dietary
> iron is important when evaluating whether iron requirements have been
> met.
>
> --------------------------------------------------------------------------=
-=AD-----
> More from this journal
> Nutrition (Burbank, Los Angeles County, Calif.) [Nutrition]
>
> Who loves ya.
> Tom
>
> Jesus Was A Vegetarian! * tinyurl . com /2r2nkh
>
> Man Is A Herbivore! * tinyurl . com /a3cc3
>
> DEAD PEOPLE WALKING * tinyurl . com /zk9fk
