Oxidative Stress and Raynaud's

"Supplementation of antioxidant molecules"

[Oxidant/antioxidant status in patients with Raynaud's disease.]
Biondi R, Coaccioli S, Lattanzi S, Puxeddu A, Papini M
Clin Ter 2008 Mar; 159(2):77-81.

Objective. Despite several studies concerning the oxidative stress in
Raynaud's phenomenon secondary to systemic sclerosis (secondary
Raynaud, SR), little is known regarding the relationship between Ray-
naud's disease (primary Raynaud, PR) and oxidative stress at present.
The aim of the present research was to study the parameters of
oxidative stress in PR patients and to compare them to those of SR
patients.Materials and Methods. Serum hydroperoxide (Hydrop) level,
serum total antioxidant capacity (TAC) and serum total thiol (-SHp)
barrier were measured in 19 patients with SR, 15 patients with PR and
14 healthy control subjects (CS). The statistical contrasts were
performed via one-way ANOVA.
Results. The serum Hydrop concentrations were significantly higher in
SR (p = 0.0043) and PR (p = 0.0038) groups in comparison with CS. A
signifi cant decrease in serum TAC level in SR (p = 0.00005) and PR (p
= 0.00128) patients in respect to the CS was revealed. No signifi cant
change in the -SHp barrier in SR and PR patients in respect to CS has
been demonstrated. However, there were no signifi cant differences in
serum Hydrop and TAC levels between the groups of patients.
Conclusions. The study of serum oxidative stress parameters, in terms
of Hydro and TAC levels may be used as a routine and rapid test to
verify the oxidative stress status in SR and PR patients and to
undertake a strategy of treatments by a supplementation of antioxidant
molecules.
La Clinica terapeutica [Clin Ter]
--------------------------------------------------------------------------------

Who loves ya.
Tom


Jesus Was A Vegetarian!
* tinyurl . com /2r2nkh


Man Is A Herbivore!
* tinyurl . com /a3cc3


DEAD PEOPLE WALKING
* tinyurl . com /zk9fk